Page last updated: 2024-11-04

suramin and Atherogenesis

suramin has been researched along with Atherogenesis in 2 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Uchida, T1
Oda, T1
Yamamoto, T1
Inamitsu, M1
Sakai, C1
Uchinoumi, H1
Suetomi, T1
Nakamura, Y1
Okamoto, Y1
Tateda, S1
Fujii, S1
Tanaka, S1
Nawata, J1
Okamura, T1
Kobayashi, S1
Yano, M1
Guns, PJ1
Hendrickx, J1
Van Assche, T1
Fransen, P1
Bult, H1

Other Studies

2 other studies available for suramin and Atherogenesis

ArticleYear
Endoplasmic reticulum stress promotes nuclear translocation of calmodulin, which activates phenotypic switching of vascular smooth muscle cells.
    Biochemical and biophysical research communications, 2022, 11-05, Volume: 628

    Topics: Animals; Atherosclerosis; Calmodulin; Dantrolene; Endoplasmic Reticulum Stress; Mice; Muscle, Smooth

2022
P2Y receptors and atherosclerosis in apolipoprotein E-deficient mice.
    British journal of pharmacology, 2010, Jan-01, Volume: 159, Issue:2

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Line; Interleukin-6; Macrophages; Mice; Mic

2010