suramin has been researched along with Asthma in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, F | 1 |
| Su, X | 1 |
| Huang, G | 1 |
| Xin, XF | 1 |
| Cao, EH | 1 |
| Shi, Y | 1 |
| Song, Y | 1 |
| Calvén, J | 1 |
| Akbarshahi, H | 1 |
| Menzel, M | 1 |
| Ayata, CK | 1 |
| Idzko, M | 2 |
| Bjermer, L | 1 |
| Uller, L | 1 |
| Hammad, H | 1 |
| van Nimwegen, M | 1 |
| Kool, M | 1 |
| Willart, MA | 1 |
| Muskens, F | 1 |
| Hoogsteden, HC | 1 |
| Luttmann, W | 1 |
| Ferrari, D | 1 |
| Di Virgilio, F | 1 |
| Virchow, JC | 1 |
| Lambrecht, BN | 1 |
3 other studies available for suramin and Asthma
| Article | Year |
|---|---|
Adenosine Triphosphate Promotes Allergen-Induced Airway Inflammation and Th17 Cell Polarization in Neutrophilic Asthma.
Topics: Adenosine Triphosphate; Allergens; Animals; Apyrase; Asthma; Cell Differentiation; Cells, Cultured; | 2017 |
Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33.
Topics: Adenosine Triphosphate; Asthma; Bronchi; Cells, Cultured; Culture Media, Conditioned; DEAD Box Prote | 2015 |
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells.
Topics: Adenosine Triphosphate; Animals; Asthma; Cell Differentiation; Dendritic Cells; Humans; Inflammation | 2007 |