suramin has been researched along with Anesthesia in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin was without effect on heart rate or blood pressure in the doses used." | 1.29 | Reversal by suramin of neuromuscular block produced by pancuronium in the anaesthetized rat. ( Agoston, S; Henning, RH; Houwertjes, M; Nelemans, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lacroix, JS | 1 |
| Ulman, LG | 1 |
| Potter, EK | 1 |
| Henning, RH | 1 |
| Nelemans, A | 1 |
| Houwertjes, M | 1 |
| Agoston, S | 1 |
| Masaki, E | 1 |
| Ebisawa, T | 1 |
| Kondo, I | 1 |
| Hayashida, K | 1 |
| Matsumoto, Y | 1 |
| Kawamura, M | 1 |
3 other studies available for suramin and Anesthesia
| Article | Year |
|---|---|
The role of ATP in non-adrenergic sympathetic vascular control of the nasal mucosa in anaesthetized cats and dogs.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Anesthesia; Animals; Arteries; Blood Pressure; Cats; | 1994 |
Reversal by suramin of neuromuscular block produced by pancuronium in the anaesthetized rat.
Topics: 4-Aminopyridine; Anesthesia; Animals; Electric Stimulation; Isometric Contraction; Male; Neostigmine | 1993 |
P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics.
Topics: Adenosine Triphosphate; Anesthesia; Anesthetics, Inhalation; Animals; Antineoplastic Agents; Brain; | 2000 |