suramin has been researched along with Anaplastic Astrocytoma in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gallagher, CJ | 1 |
| Salter, MW | 1 |
| Rodrigues, RJ | 1 |
| Almeida, T | 1 |
| Richardson, PJ | 1 |
| Oliveira, CR | 1 |
| Cunha, RA | 1 |
| Trujillo, CA | 1 |
| Majumder, P | 1 |
| Gonzalez, FA | 1 |
| Moaddel, R | 1 |
| Ulrich, H | 1 |
3 other studies available for suramin and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors.
Topics: Adenosine Triphosphate; Animals; Apyrase; Astrocytes; Astrocytoma; Calcium; Calcium Signaling; Cells | 2003 |
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calc | 2005 |
Immobilized P2X2 purinergic receptor stationary phase for chromatographic determination of pharmacological properties and drug screening.
Topics: Adenosine Triphosphate; Animals; Astrocytoma; Binding, Competitive; Cell Culture Techniques; Cell Li | 2007 |