suramin has been researched along with Aging in 7 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sacramento, JF | 1 |
| Olea, E | 1 |
| Ribeiro, MJ | 1 |
| Prieto-Lloret, J | 1 |
| Melo, BF | 1 |
| Gonzalez, C | 1 |
| Martins, FO | 1 |
| Monteiro, EC | 1 |
| Conde, SV | 1 |
| Stöhr, J | 1 |
| Novotny, J | 1 |
| Svoboda, P | 1 |
| Wallace, A | 1 |
| Knight, GE | 1 |
| Cowen, T | 1 |
| Burnstock, G | 1 |
| Ng, YK | 1 |
| de Groat, WC | 1 |
| Wu, HY | 1 |
| Ragazzi, E | 1 |
| Chinellato, A | 1 |
| Pandolfo, L | 1 |
| Froldi, G | 1 |
| Caparrotta, L | 1 |
| Aliev, G | 1 |
| Prosdocimi, M | 1 |
| Fassina, G | 1 |
| Kondo, H | 1 |
| Yonezawa, Y | 1 |
| Büttner, DW | 1 |
| Albiez, EJ | 1 |
| von Essen, J | 1 |
| Erichsen, J | 1 |
7 other studies available for suramin and Aging
| Article | Year |
|---|---|
Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing.
Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; Antinematodal Agents; Carotid Body; Chemoreceptor | 2019 |
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding.
Topics: Adrenergic beta-Agonists; Aging; Animals; Baclofen; Binding, Competitive; Cell Membrane; Cerebral Co | 2005 |
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonis | 2006 |
Smooth muscle and neural mechanisms contributing to the downregulation of neonatal rat spontaneous bladder contractions during postnatal development.
Topics: Aging; Animals; Atropine; Down-Regulation; Muscarinic Antagonists; Muscle Contraction; Muscle, Smoot | 2007 |
Endothelial nucleotide-mediated aorta relaxation in aged Watanabe heritable hyperlipidemic rabbits.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Aorta, Thoracic; Arginine; Arteriosclerosis; | 1995 |
Changes in the migratory ability of human lung and skin fibroblasts during in vitro aging and in vivo cellular senescence.
Topics: Adult; Aged; Aging; Cell Line; Cell Movement; Cellular Senescence; Fibroblasts; Humans; In Vitro Tec | 1992 |
Histological examination of adult Onchocerca volvulus and comparison with the collagenase technique.
Topics: Aging; Animals; Female; Filaricides; Humans; Male; Microbial Collagenase; Microfilariae; Microscopy, | 1988 |