Compounds > suramin
Page last updated: 2024-11-04

suramin and Adrenal Insufficiency

suramin has been researched along with Adrenal Insufficiency in 3 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
AZERAD, E1
GRUPPER, C1
MAHONEY, LJ1
BARRIE, HJ1
THIERS, H1
ROMAGNY, G1

Other Studies

3 other studies available for suramin and Adrenal Insufficiency

ArticleYear
[Addison's disease, pemphigus and moranyl].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1953, May-02, Volume: 29, Issue:29

    Topics: Addison Disease; Adrenal Insufficiency; Hypoadrenocorticism, Familial; Pemphigus; Suramin

1953
Adrenal insufficiency after suramin treatment of pemphigus.
    British medical journal, 1950, Sep-16, Volume: 2, Issue:4680

    Topics: Adrenal Glands; Adrenal Insufficiency; Pemphigus; Pregnancy; Suramin

1950
[Addison's syndrome in a woman with chronic pemphigus, treated by moranyl. Acute adrenal insufficiency brought about by aureomycin].
    Lyon medical, 1951, Sep-23, Volume: 185, Issue:38

    Topics: Adrenal Insufficiency; Chlortetracycline; Female; Humans; Pemphigus; Suramin; Syndrome

1951