suramin has been researched along with Adenoma, Prostatic in 6 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tatoud, R | 1 |
| Desgrandchamps, F | 1 |
| DeGeorges, A | 1 |
| Thomas, F | 1 |
| Peehl, DM | 2 |
| Leung, GK | 1 |
| Wong, ST | 2 |
| De Angeli, S | 2 |
| Fandella, A | 2 |
| Conconi, MT | 1 |
| Anselmo, G | 2 |
| Parnigotto, PP | 2 |
| Mitchen, J | 1 |
| Rago, R | 1 |
| Wilding, G | 1 |
| Buoro, S | 1 |
| Palù, G | 1 |
| Mingrino, R | 1 |
| Stamey, TA | 1 |
1 review available for suramin and Adenoma, Prostatic
| Article | Year |
|---|---|
[Peptide growth factors in the prostate].
Topics: Adenocarcinoma; Epidermal Growth Factor; Fibroblast Growth Factors; Humans; Interleukin-6; Male; Ner | 1993 |
5 other studies available for suramin and Adenoma, Prostatic
| Article | Year |
|---|---|
Keratin expression: a measure of phenotypic modulation of human prostatic epithelial cells by growth inhibitory factors.
Topics: Cell Division; Cells, Cultured; Epithelial Cells; Epithelium; Glucose; Growth Substances; Humans; In | 1994 |
Growth, morphology, and morphometry of human hypertrophic prostate cells treated with suramin in vitro.
Topics: Cell Division; Cell Size; Cells, Cultured; Humans; Male; Microscopy, Electron, Scanning; Prostatic H | 1994 |
Effects of suramin on the proliferation of primary epithelial cell cultures derived from normal, benign hyperplastic and cancerous human prostates.
Topics: Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Epit | 1993 |
Production of epidermal growth factor in human prostatic cells cultured in vitro.
Topics: Analysis of Variance; Cell Division; Cell Line; Cell Survival; Epidermal Growth Factor; ErbB Recepto | 2000 |
Cytostatic effects of suramin on prostate cancer cells cultured from primary tumors.
Topics: Cell Division; Growth Substances; Humans; Immunoblotting; In Vitro Techniques; Male; Prostate; Prost | 1991 |