suramin has been researched along with Acute Disease in 5 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Acute Disease: Disease having a short and relatively severe course.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dixit, A | 1 |
| Cheema, H | 1 |
| George, J | 1 |
| Iyer, S | 1 |
| Dudeja, V | 1 |
| Dawra, R | 1 |
| Saluja, AK | 1 |
| Ayata, CK | 1 |
| Ganal, SC | 1 |
| Hockenjos, B | 1 |
| Willim, K | 1 |
| Vieira, RP | 1 |
| Grimm, M | 1 |
| Robaye, B | 1 |
| Boeynaems, JM | 1 |
| Di Virgilio, F | 1 |
| Pellegatti, P | 1 |
| Diefenbach, A | 1 |
| Idzko, M | 1 |
| Hasselblatt, P | 1 |
| Abe, S | 1 |
| Funato, T | 1 |
| Takahashi, S | 1 |
| Yokoyama, H | 1 |
| Yamamoto, J | 1 |
| Tomiya, Y | 1 |
| Yamada-Fujiwara, M | 1 |
| Ishizawa, K | 1 |
| Kameoka, J | 1 |
| Kaku, M | 1 |
| Harigae, H | 1 |
| Sasaki, T | 1 |
| Mahmoud, AA | 1 |
| Warren, KS | 1 |
| Vakulin, GM | 1 |
| Korolenko, TA | 1 |
| Pupyshev, AB | 1 |
| Malygin, AE | 1 |
| Kurysheva, NG | 1 |
5 other studies available for suramin and Acute Disease
| Article | Year |
|---|---|
Extracellular release of ATP promotes systemic inflammation during acute pancreatitis.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Apyrase; Arginine; Bronchoalveolar Lavage Fluid; Cer | 2019 |
Purinergic P2Y₂ receptors promote neutrophil infiltration and hepatocyte death in mice with acute liver injury.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Apoptosis; Cell Movement; Chemical and Drug Induced | 2012 |
Increased expression of insulin-like growth factor i is associated with Ara-C resistance in leukemia.
Topics: Acute Disease; Adult; Aged; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expressio | 2006 |
Algorithms in the diagnosis and management of exotic diseases. XI. African trypanosomiases.
Topics: Acute Disease; Blood; Blood Sedimentation; Cerebrospinal Fluid; Chronic Disease; Humans; Lymph Nodes | 1976 |
[Effect of the lysosomotropic preparation suramin on the ultrastructural and functional characteristics of rat liver cells in acute toxic hepatitis].
Topics: Acute Disease; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Live | 1986 |