Page last updated: 2024-11-04

suprofen and Dysmenorrhea

suprofen has been researched along with Dysmenorrhea in 6 studies

Suprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
suprofen : An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.

Dysmenorrhea: Painful menstruation.

Research Excerpts

ExcerptRelevanceReference
"Eleven women with primary dysmenorrhea completed a randomized, double-blind, placebo-controlled, three-way cross-over study comparing 200 and 400mg suprofen."9.12Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea. ( Dawood, MY; Khan-Dawood, FS, 2007)
"Eleven women with primary dysmenorrhea completed a randomized, double-blind, placebo-controlled, three-way cross-over study comparing 200 and 400mg suprofen."5.12Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea. ( Dawood, MY; Khan-Dawood, FS, 2007)
"Suprofen (sutoprofen) is a non-steroidal anti-inflammatory analgesic, closely related structurally to drugs such as ibuprofen, ketoprofen and naproxen."3.75Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy. ( Heel, RC; Todd, PA, 1985)
"An in situ model for studying factors related to dysmenorrhea and for evaluating drugs for their inhibitory effects on uterine contractility induced by arachidonic acid and prostaglandins has been developed."3.66Effects of suprofen and other prostaglandin synthetase inhibitors in a new animal model for myometrial hyperactivity. ( Carraher, R; Hahn, DW; McGuire, JL, 1982)
"Suprofen is a new and potent peripherally acting analgesic with anti-inflammatory and antipyretic properties which appears to inhibit prostaglandin synthetase in a tissue-selective manner."2.36Introduction to the pharmacology of suprofen. ( Capetola, RJ; McGuire, JL; Rosenthale, ME, 1983)
"Suprofen is a non-narcotic, peripheral analgesic that exhibits potent prostaglandin (PG) synthesis inhibitory activities in a variety of subcellular tissue preparations and in vivo."1.27Potent and selective effects of suprofen on uterine prostaglandin synthesis. ( Fuller, BL; Rosenthale, ME; Tolman, EL, 1985)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dawood, MY1
Khan-Dawood, FS1
Capetola, RJ1
McGuire, JL2
Rosenthale, ME2
Hahn, DW1
Carraher, R1
Todd, PA1
Heel, RC1
Tolman, EL1
Fuller, BL1

Reviews

2 reviews available for suprofen and Dysmenorrhea

ArticleYear
Introduction to the pharmacology of suprofen.
    Pharmacology, 1983, Volume: 27 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry; Dysm

1983
Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.
    Drugs, 1985, Volume: 30, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; D

1985

Trials

3 trials available for suprofen and Dysmenorrhea

ArticleYear
Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea.
    Prostaglandins & other lipid mediators, 2007, Volume: 83, Issue:1-2

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Body Fluids; Dinoprost

2007
Suprofen.
    The Medical letter on drugs and therapeutics, 1986, May-23, Volume: 28, Issue:714

    Topics: Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Pain; Phenylpropionates; Suprof

1986
Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.
    Drugs, 1985, Volume: 30, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; D

1985

Other Studies

2 other studies available for suprofen and Dysmenorrhea

ArticleYear
Effects of suprofen and other prostaglandin synthetase inhibitors in a new animal model for myometrial hyperactivity.
    Prostaglandins, 1982, Volume: 23, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Catecholamines; Cyclooxygenase Inhibitors;

1982
Potent and selective effects of suprofen on uterine prostaglandin synthesis.
    Prostaglandins, leukotrienes, and medicine, 1985, Volume: 18, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dysmenorrhea; Female; Guinea Pigs; Ibuprofen; Phenylpr

1985