suprofen has been researched along with Ache in 25 studies
Suprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
suprofen : An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of spontaneous reporting in detecting the suprofen-associated flank pain syndrome was examined, including the specific effect of the "Dear Doctor" letter in accelerating the information-gathering process once the initial signal was generated." | 9.06 | The importance of adverse reaction reporting by physicians. Suprofen and the flank pain syndrome. ( Bosco, L; Faich, GA; Rossi, AC; Tanner, A; Temple, R, 1988) |
| "In a placebo-controlled double-blind trial analgesic effectiveness and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) 300 mg suppositories were evaluated for 45 informed patients suffering from chronic pain due to osteoarthritis; the subjects were treated rectally, t." | 9.06 | Double-blind placebo-controlled study of the efficacy and tolerability of suprofen suppositories in patients with osteoarthritic pain. ( Menicanti, V; Michos, N; Nebiolo, M; Sarchi, C; Viara, M, 1986) |
| "43 patients with osteoarthritis of the knee and/or hip(s) were treated with suprofen 800 mg/day or ibuprofen 1,600 mg/day for 14 days." | 9.05 | Comparison of suprofen and ibuprofen in the treatment of pain secondary to osteoarthritis. ( Schuermans, Y, 1983) |
| "The effectiveness and safety of suprofen 200 mg, aspirin 650 mg, and placebo in the treatment of moderate to severe pain were compared in a 72-hour multiple-dose, double-blind, parallel, randomized study in 75 adults suffering from musculoskeletal pain." | 9.05 | Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. ( Silberman, HM, 1983) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 9.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "Suprofen, a nonsteroidal anti-inflammatory drug, has been associated with the onset of acute flank pain, hematuria, and transient renal dysfunction after the ingestion of one or two doses, particularly in young males." | 7.67 | Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain. ( Abraham, PA; Halstenson, CE; Keane, WF; Matzke, GR; Opsahl, JA, 1988) |
| "Analgesic effect and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) drops were tested in an open study including 51 informed outpatients with moderate to severe postoperative and posttraumatic pain." | 7.67 | Open clinical study with suprofen drops in the treatment of postoperative and posttraumatic pain. ( Michos, N; Probst, G, 1986) |
| "This 4-week, open design study was conducted to evaluate the efficacy and safety of suprofen (200-1,200 mg/day) in the treatment of elderly patients with pain of diverse origin, all of whom suffered from secondary disorders." | 7.66 | Clinical evaluation of suprofen in the treatment of elderly patients with pain of diverse etiology. ( de Beer, JM; Denis, FR, 1983) |
| " Long-term administration of suprofen was at least as well tolerated as that of propoxyphene." | 6.65 | Long-term comparison of suprofen and propoxyphene in patients with osteoarthritis. ( Brobyn, RD; Salzman, RT, 1983) |
| "The role of spontaneous reporting in detecting the suprofen-associated flank pain syndrome was examined, including the specific effect of the "Dear Doctor" letter in accelerating the information-gathering process once the initial signal was generated." | 5.06 | The importance of adverse reaction reporting by physicians. Suprofen and the flank pain syndrome. ( Bosco, L; Faich, GA; Rossi, AC; Tanner, A; Temple, R, 1988) |
| "The analgesic effect and the tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) syrup 200 mg and metamizole syrup 500 mg were compared in a randomized single-blind study including hospitalized patients with severe to moderate chronic pain." | 5.06 | Controlled single-blind clinical study of suprofen syrup versus metamizole syrup. ( Michos, N; von Szeged, AV, 1986) |
| "In a placebo-controlled double-blind trial analgesic effectiveness and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) 300 mg suppositories were evaluated for 45 informed patients suffering from chronic pain due to osteoarthritis; the subjects were treated rectally, t." | 5.06 | Double-blind placebo-controlled study of the efficacy and tolerability of suprofen suppositories in patients with osteoarthritic pain. ( Menicanti, V; Michos, N; Nebiolo, M; Sarchi, C; Viara, M, 1986) |
| "43 patients with osteoarthritis of the knee and/or hip(s) were treated with suprofen 800 mg/day or ibuprofen 1,600 mg/day for 14 days." | 5.05 | Comparison of suprofen and ibuprofen in the treatment of pain secondary to osteoarthritis. ( Schuermans, Y, 1983) |
| "The effectiveness and safety of suprofen 200 mg, aspirin 650 mg, and placebo in the treatment of moderate to severe pain were compared in a 72-hour multiple-dose, double-blind, parallel, randomized study in 75 adults suffering from musculoskeletal pain." | 5.05 | Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. ( Silberman, HM, 1983) |
| "Suprofen, a new oral peripherally acting analgesic agent, has been shown to be effective in the relief of acute and chronic pain." | 5.05 | Suprofen. An overview of long-term safety. ( Gardner, MC; Milak, DM; Raina, M; Smith, KE; Yeadon, A, 1983) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 5.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "Suprofen (sutoprofen) is a non-steroidal anti-inflammatory analgesic, closely related structurally to drugs such as ibuprofen, ketoprofen and naproxen." | 3.75 | Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy. ( Heel, RC; Todd, PA, 1985) |
| "Suprofen, a nonsteroidal anti-inflammatory drug, has been associated with the onset of acute flank pain, hematuria, and transient renal dysfunction after the ingestion of one or two doses, particularly in young males." | 3.67 | Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain. ( Abraham, PA; Halstenson, CE; Keane, WF; Matzke, GR; Opsahl, JA, 1988) |
| "Analgesic effect and tolerability of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol) drops were tested in an open study including 51 informed outpatients with moderate to severe postoperative and posttraumatic pain." | 3.67 | Open clinical study with suprofen drops in the treatment of postoperative and posttraumatic pain. ( Michos, N; Probst, G, 1986) |
| "We describe a unique clinical syndrome of flank pain and acute renal failure that is associated with suprofen, a nonsteroidal anti-inflammatory drug that has recently been made available in the United States." | 3.67 | Suprofen-related nephrotoxicity. A distinct clinical syndrome. ( Hart, D; Lifschitz, MD; Ward, M, 1987) |
| "This 4-week, open design study was conducted to evaluate the efficacy and safety of suprofen (200-1,200 mg/day) in the treatment of elderly patients with pain of diverse origin, all of whom suffered from secondary disorders." | 3.66 | Clinical evaluation of suprofen in the treatment of elderly patients with pain of diverse etiology. ( de Beer, JM; Denis, FR, 1983) |
| "In a randomized double-dummy study a new dosage form of alpha-methyl-4-(2-thienyl-carbonyl)phenylacetic acid (suprofen, Suprol), i." | 2.66 | Double-dummy comparison of suprofen and indometacin sustained release formulations. ( Höbel, W; Michos, N; Schenker, H, 1986) |
| " Long-term administration of suprofen was at least as well tolerated as that of propoxyphene." | 2.65 | Long-term comparison of suprofen and propoxyphene in patients with osteoarthritis. ( Brobyn, RD; Salzman, RT, 1983) |
| "Suprofen is a potent, peripherally-acting, non-narcotic analgesic agent." | 2.37 | Suprofen: the pharmacology and clinical efficacy of a new non-narcotic peripheral analgesic. ( Capetola, RJ; McGuire, JL; Rosenthale, ME; Tolman, EL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vargha von Szeged, A | 1 |
| Michos, N | 6 |
| Schuermans, Y | 1 |
| Salzman, RT | 1 |
| Brobyn, RD | 1 |
| Silberman, HM | 1 |
| Yeadon, A | 1 |
| Raina, M | 1 |
| Gardner, MC | 1 |
| Milak, DM | 1 |
| Smith, KE | 1 |
| Tolman, EL | 1 |
| Rosenthale, ME | 1 |
| Capetola, RJ | 1 |
| McGuire, JL | 1 |
| Denis, FR | 1 |
| de Beer, JM | 1 |
| Colpaert, FC | 1 |
| De Witte, P | 1 |
| Maroli, AN | 1 |
| Awouters, F | 1 |
| Niemegeers, CJ | 1 |
| Janssen, PA | 1 |
| Strom, BL | 1 |
| West, SL | 1 |
| Sim, E | 1 |
| Carson, JL | 1 |
| Rossi, AC | 1 |
| Bosco, L | 1 |
| Faich, GA | 1 |
| Tanner, A | 1 |
| Temple, R | 1 |
| Abraham, PA | 1 |
| Halstenson, CE | 1 |
| Opsahl, JA | 1 |
| Matzke, GR | 1 |
| Keane, WF | 1 |
| von Szeged, AV | 1 |
| Viara, M | 1 |
| Menicanti, V | 1 |
| Nebiolo, M | 1 |
| Sarchi, C | 1 |
| Wolfe, SM | 1 |
| Talmud, J | 1 |
| Davey, J | 1 |
| Schenker, H | 1 |
| Höbel, W | 1 |
| Probst, G | 1 |
| Hart, D | 1 |
| Ward, M | 1 |
| Lifschitz, MD | 1 |
| Henann, NE | 1 |
| Morales, JR | 1 |
| Amantea, B | 1 |
| Savoia, G | 1 |
| Belfiore, F | 1 |
| Esposito, C | 1 |
| Cuocolo, R | 1 |
| Weippl, G | 1 |
| Stocker, H | 1 |
| Todd, PA | 1 |
| Heel, RC | 1 |
2 reviews available for suprofen and Ache
| Article | Year |
|---|---|
Suprofen: the pharmacology and clinical efficacy of a new non-narcotic peripheral analgesic.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Drug Evaluation, Preclinical; Fem | 1984 |
Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; D | 1985 |
12 trials available for suprofen and Ache
| Article | Year |
|---|---|
[Experience with suprofen for acute and chronic pain in neurologic practice].
Topics: Acute Disease; Adult; Aspirin; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug | 1983 |
Comparison of suprofen and ibuprofen in the treatment of pain secondary to osteoarthritis.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; M | 1983 |
Long-term comparison of suprofen and propoxyphene in patients with osteoarthritis.
Topics: Aged; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Drug Interactions; Female; | 1983 |
Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain.
Topics: Adolescent; Adult; Aged; Aspirin; Bone Diseases; Clinical Trials as Topic; Dose-Response Relationshi | 1983 |
Suprofen. An overview of long-term safety.
Topics: Adult; Aged; Aspirin; Blood Chemical Analysis; Clinical Trials as Topic; Dextropropoxyphene; Double- | 1983 |
The importance of adverse reaction reporting by physicians. Suprofen and the flank pain syndrome.
Topics: Acute Kidney Injury; Clinical Trials as Topic; Data Collection; Drug Industry; Europe; Humans; Pain; | 1988 |
Suprofen.
Topics: Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Pain; Phenylpropionates; Suprof | 1986 |
Controlled single-blind clinical study of suprofen syrup versus metamizole syrup.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Methimazole; Middle Ag | 1986 |
Double-blind placebo-controlled study of the efficacy and tolerability of suprofen suppositories in patients with osteoarthritic pain.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Osteoarthritis; Pain; Ph | 1986 |
Double-dummy comparison of suprofen and indometacin sustained release formulations.
Topics: Aged; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle A | 1986 |
Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; In | 1985 |
Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; D | 1985 |
12 other studies available for suprofen and Ache
| Article | Year |
|---|---|
Clinical evaluation of suprofen in the treatment of elderly patients with pain of diverse etiology.
Topics: Aged; Female; Humans; Male; Middle Aged; Pain; Phenylpropionates; Suprofen; Time Factors | 1983 |
Self-administration of the analgesic suprofen in arthritic rats: evidence of Mycobacterium butyricum-induced arthritis as an experimental model of chronic pain.
Topics: Animals; Arthritis; Arthritis, Experimental; Chronic Disease; Conditioning, Psychological; Disease M | 1980 |
The epidemiology of the acute flank pain syndrome from suprofen.
Topics: Acute Kidney Injury; Adult; Asthma; Case-Control Studies; Exercise; Female; Humans; Incidence; Kidne | 1989 |
Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain.
Topics: Acute Disease; Adult; Humans; Kidney Concentrating Ability; Kidney Diseases; Male; Pain; Phenylpropi | 1988 |
Suprofen-induced transient flank pain and renal failure.
Topics: Acute Kidney Injury; Adult; Hip; Humans; Male; Pain; Phenylpropionates; Suprofen; Uricosuric Agents | 1987 |
Suprofen, flank pain and renal involvement: a case report.
Topics: Abdomen; Adult; Humans; Kidney; Male; Pain; Phenylpropionates; Suprofen | 1987 |
Adverse reaction reported with suprofen.
Topics: Creatinine; Humans; Pain; Phenylpropionates; Suprofen; United States; United States Food and Drug Ad | 1986 |
Open clinical study with suprofen drops in the treatment of postoperative and posttraumatic pain.
Topics: Adult; Female; Humans; Male; Middle Aged; Pain; Pain, Postoperative; Phenylpropionates; Suprofen; Wo | 1986 |
Suprofen-related nephrotoxicity. A distinct clinical syndrome.
Topics: Abdomen; Acute Kidney Injury; Adolescent; Adult; Female; Humans; Male; Middle Aged; Pain; Phenylprop | 1987 |
Suprofen-induced acute renal failure revisited.
Topics: Acute Kidney Injury; Adult; Humans; Male; Pain; Phenylpropionates; Suprofen | 1987 |
Suprofen labeling revised.
Topics: Back; Drug Labeling; Humans; Kidney Diseases; Pain; Phenylpropionates; Suprofen | 1986 |
[Somatosensory evoked potentials in pain studies].
Topics: Adult; Buprenorphine; Evoked Potentials, Somatosensory; Humans; Morphine; Naloxone; Pain; Recruitmen | 1985 |