Page last updated: 2024-11-04

sumatriptan and Trigeminal Neuralgia

sumatriptan has been researched along with Trigeminal Neuralgia in 7 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Trigeminal Neuralgia: A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)

Research Excerpts

ExcerptRelevanceReference
"To examine the effectiveness of a 5-HT(1B/1D) receptor agonist, sumatriptan, on a paroxysmal pain in trigeminal neuralgia."9.12Subcutaneous sumatriptan for refractory trigeminal neuralgia. ( Hoka, S; Kanai, A; Saito, M, 2006)
" The present study examined the effectiveness of a 5-HT1A/1B/1D receptor agonist, sumatriptan, on pain relief in patients with trigeminal neuralgia."9.12Sumatriptan alleviates pain in patients with trigeminal neuralgia. ( Hoka, S; Kanai, A; Osawa, S; Suzuki, A, 2006)
"We examine the effect of nasal sumatriptan as an adjunctive therapy in 3 patients with idiopathic trigeminal neuralgia refractory to carbamazepine (CBZ) and found that this therapy might be suitable for patients for whom the CBZ dose cannot be increased, who are under poor pain control, and who are not candidates for nerve blocks or surgery."7.75Nasal sumatriptan as adjunctive therapy for idiopathic trigeminal neuralgia: report of three cases. ( Miyashita, K; Motegi, R; Shimohata, K; Shimohata, T, 2009)
"To examine the effectiveness of a 5-HT(1B/1D) receptor agonist, sumatriptan, on a paroxysmal pain in trigeminal neuralgia."5.12Subcutaneous sumatriptan for refractory trigeminal neuralgia. ( Hoka, S; Kanai, A; Saito, M, 2006)
" The present study examined the effectiveness of a 5-HT1A/1B/1D receptor agonist, sumatriptan, on pain relief in patients with trigeminal neuralgia."5.12Sumatriptan alleviates pain in patients with trigeminal neuralgia. ( Hoka, S; Kanai, A; Osawa, S; Suzuki, A, 2006)
" Attack treatment in cluster headache is based on sumatriptan and oxygen."4.82[Treatment of cluster headache]. ( Fabre, N, 2005)
"We examine the effect of nasal sumatriptan as an adjunctive therapy in 3 patients with idiopathic trigeminal neuralgia refractory to carbamazepine (CBZ) and found that this therapy might be suitable for patients for whom the CBZ dose cannot be increased, who are under poor pain control, and who are not candidates for nerve blocks or surgery."3.75Nasal sumatriptan as adjunctive therapy for idiopathic trigeminal neuralgia: report of three cases. ( Miyashita, K; Motegi, R; Shimohata, K; Shimohata, T, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimohata, K1
Shimohata, T1
Motegi, R1
Miyashita, K1
Matharu, MS1
Boes, CJ1
Goadsby, PJ2
Fabre, N1
Kanai, A2
Saito, M1
Hoka, S2
Suzuki, A1
Osawa, S1
Hoskin, KL1
Autret, A1
Mondon, K1

Reviews

2 reviews available for sumatriptan and Trigeminal Neuralgia

ArticleYear
Management of trigeminal autonomic cephalgias and hemicrania continua.
    Drugs, 2003, Volume: 63, Issue:16

    Topics: Analgesics; Anesthetics, Local; Drug Administration Schedule; Ergot Alkaloids; Female; Humans; Male;

2003
[Treatment of cluster headache].
    Revue neurologique, 2005, Volume: 161, Issue:6-7

    Topics: Cluster Headache; Facial Pain; Headache; Humans; Oxygen Inhalation Therapy; Sumatriptan; Trigeminal

2005

Trials

2 trials available for sumatriptan and Trigeminal Neuralgia

ArticleYear
Subcutaneous sumatriptan for refractory trigeminal neuralgia.
    Headache, 2006, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Fatigue; Female; Humans; Injections, Subcutaneou

2006
Sumatriptan alleviates pain in patients with trigeminal neuralgia.
    The Clinical journal of pain, 2006, Volume: 22, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Female; Humans; Male; Middle Aged; Pain; Pain Measuremen

2006

Other Studies

3 other studies available for sumatriptan and Trigeminal Neuralgia

ArticleYear
Nasal sumatriptan as adjunctive therapy for idiopathic trigeminal neuralgia: report of three cases.
    Headache, 2009, Volume: 49, Issue:5

    Topics: Administration, Intranasal; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug;

2009
Differential effects of low dose CP122,288 and eletriptan on fos expression due to stimulation of the superior sagittal sinus in cat.
    Pain, 1999, Volume: 82, Issue:1

    Topics: Animals; Cats; Cranial Sinuses; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evalu

1999
[Migraine and facial pain].
    La Revue du praticien, 2001, Oct-15, Volume: 51, Issue:16

    Topics: Adult; Analgesics; Analgesics, Non-Narcotic; Carbamazepine; Child; Diagnosis, Differential; Dihydroe

2001