sumatriptan has been researched along with Torsade de Pointes in 2 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sumatriptan manufacturer-provided drug information states that life threatening arrhythmias, including ventricular tachycardia and ventricular fibrillation (VF), have been reported." | 4.90 | Triptan-induced torsades de pointes and ventricular fibrillation cardiac arrest: case report and review of the literature. ( Hill, SE; Kirsten, L, 2014) |
| "Part 1 discusses the risks for Torsade de Pointes, vasospasm, and ischemia, with a review and discussion of case reports of triptan-associated cardiovascular events in migraineurs with and without CAD risk factors or documented CAD; of the epidemiology and studies of triptans, vasospasm, and cardiovascular morbidity; and of the relationship of variant angina, migraine, and vasospastic disease." | 2.49 | QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, and headache medications. Part 1: review of serotonergic cardiac adverse events with a triptan case. ( Cho, L; Stillman, MJ; Tepper, DE; Tepper, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hill, SE | 1 |
| Kirsten, L | 1 |
| Stillman, MJ | 1 |
| Tepper, S | 1 |
| Tepper, DE | 1 |
| Cho, L | 1 |
2 reviews available for sumatriptan and Torsade de Pointes
| Article | Year |
|---|---|
Triptan-induced torsades de pointes and ventricular fibrillation cardiac arrest: case report and review of the literature.
Topics: Adult; Female; Heart Arrest; Humans; Sumatriptan; Torsades de Pointes; Vasoconstrictor Agents; Ventr | 2014 |
QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, and headache medications. Part 1: review of serotonergic cardiac adverse events with a triptan case.
Topics: Coronary Vasospasm; Electrocardiography; Female; Humans; Middle Aged; Migraine Disorders; Myocardial | 2013 |