sumatriptan has been researched along with Substance-Related Disorders in 9 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Substance-Related Disorders: Disorders related to substance use or abuse.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sumatriptan is a 5-HT1D agonist of therapeutic use in migraine and cluster headaches." | 2.67 | Psychoactivity and abuse potential of sumatriptan. ( Busch, M; Jasinski, DR; Preston, KL; Sullivan, JT; Testa, MP, 1992) |
| "No drug abuse was recorded, but bleeding occurred after the use of several antimigrainous drugs." | 1.30 | Multiple intracerebral hemorrhages and vasospasm following antimigrainous drug abuse. ( Derex, L; Nighoghossian, N; Trouillas, P, 1998) |
| " Pharmacokinetic and pharmacodynamic variables were similar in all groups studied and were not altered by the presence of food, alcohol, dihydroergotamine or prophylactic migraine treatments." | 1.28 | The clinical pharmacology, pharmacokinetics and metabolism of sumatriptan. ( Baber, NS; Fowler, PA; Keene, ON; Lacey, LF; Tanner, RJ; Thomas, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verslegers, WR | 1 |
| Leone, M | 1 |
| Proietti Cecchini, A | 1 |
| Beau-Salinas, F | 1 |
| Jonville-Béra, AP | 1 |
| Cissoko, H | 1 |
| Bensouda-Grimaldi, L | 1 |
| Autret-Leca, E | 1 |
| Lampl, C | 1 |
| Buzath, A | 1 |
| Yazdi, K | 1 |
| Sandor, PS | 1 |
| Gaist, D | 1 |
| Sindrup, S | 1 |
| Hallas, J | 1 |
| Gram, LF | 1 |
| Osborne, MJ | 1 |
| Austin, RC | 1 |
| Dawson, KJ | 1 |
| Lange, L | 1 |
| Nighoghossian, N | 1 |
| Derex, L | 1 |
| Trouillas, P | 1 |
| Goadsby, PJ | 1 |
| Sullivan, JT | 1 |
| Preston, KL | 1 |
| Testa, MP | 1 |
| Busch, M | 1 |
| Jasinski, DR | 1 |
| Fowler, PA | 1 |
| Lacey, LF | 1 |
| Thomas, M | 1 |
| Keene, ON | 1 |
| Tanner, RJ | 1 |
| Baber, NS | 1 |
1 trial available for sumatriptan and Substance-Related Disorders
| Article | Year |
|---|---|
Psychoactivity and abuse potential of sumatriptan.
Topics: Adult; Affect; Analysis of Variance; Dose-Response Relationship, Drug; Double-Blind Method; Humans; | 1992 |
8 other studies available for sumatriptan and Substance-Related Disorders
| Article | Year |
|---|---|
Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache.
Topics: Cluster Headache; Humans; Injections, Subcutaneous; Substance-Related Disorders; Sumatriptan | 2016 |
Drug dependence associated with triptans and ergot derivatives: a case/non-case study.
Topics: Claviceps; Dihydroergotamine; Ergotamine; Humans; Migraine Disorders; Oxazolidinones; Piperidines; P | 2010 |
Ergot and triptan overuse in Austria--an evaluation of clinical data and cost.
Topics: Adult; Aged; Austria; Ergot Alkaloids; Female; Headache; Humans; Male; Middle Aged; Oxazolidinones; | 2002 |
Misuse of sumatriptan.
Topics: Adult; Aged; Denmark; Female; Humans; Male; Middle Aged; Product Surveillance, Postmarketing; Substa | 1994 |
Is there a problem with long-term use of sumatriptan in migraine.
Topics: Humans; Male; Middle Aged; Migraine Disorders; Substance-Related Disorders; Sumatriptan | 1994 |
Multiple intracerebral hemorrhages and vasospasm following antimigrainous drug abuse.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Cerebral Hemorrhage; Ergotamine; Female; Humans; Isc | 1998 |
Sumatriptan is not the only analgesic used inappropriately.
Topics: Analgesics; Health Services Misuse; Humans; Migraine Disorders; Substance-Related Disorders; Sumatri | 1998 |
The clinical pharmacology, pharmacokinetics and metabolism of sumatriptan.
Topics: Aged; Aged, 80 and over; Biological Availability; Drug Administration Schedule; Drug Interactions; F | 1991 |