sumatriptan has been researched along with Stroke in 7 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects." | 8.12 | Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022) |
| "A 23-year-old woman developed ischemic stroke (IS) 8 to 12 hours after ingestion of sumatriptan (ST) and then developed mucosal bleeding secondary to acute thrombocytopenia likely due to dipyridamole (DP) on the 10th day poststroke." | 4.87 | Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy. ( Adams, C; Ames, PR; Dhirendra, A, 2011) |
| " In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects." | 4.12 | Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022) |
| "Triptans, 5-HT1B/1D agonists used in migraine treatment, are rarely involved in serious coronary events due to vasospasm." | 2.41 | [Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause]. ( Hedenmalm, K, 2000) |
| "Triptans are widely used to treat migraine but have been associated with stroke, myocardial infarction (MI), and ischemic heart disease (IHD) in case reports." | 1.32 | Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice. ( Brown, MM; Hall, GC; MacRae, KD; Mo, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Shayan, M | 1 |
| Eslami, F | 1 |
| Amanlou, A | 1 |
| Solaimanian, S | 1 |
| Rahimi, N | 1 |
| Rashidian, A | 1 |
| Ejtemaei-Mehr, S | 1 |
| Ghasemi, M | 1 |
| Dehpour, AR | 1 |
| Rothrock, JF | 1 |
| Adams, C | 1 |
| Dhirendra, A | 1 |
| Ames, PR | 1 |
| Petro, DJ | 1 |
| Hall, GC | 1 |
| Brown, MM | 1 |
| Mo, J | 1 |
| MacRae, KD | 1 |
| Hedenmalm, K | 1 |
2 reviews available for sumatriptan and Stroke
| Article | Year |
|---|---|
Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy.
Topics: Acute Disease; Adult; Brain Ischemia; Dipyridamole; Female; Hemorrhage; Humans; Iatrogenic Disease; | 2011 |
[Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause].
Topics: Contraindications; Coronary Disease; Humans; Migraine Disorders; Myocardial Infarction; Risk Assessm | 2000 |
5 other studies available for sumatriptan and Stroke
| Article | Year |
|---|---|
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Mo | 2022 |
Margaritas... not science.
Topics: Biomedical Research; Causality; Cerebrovascular Circulation; Clinical Trials as Topic; Drug Design; | 2009 |
Cerebral vasoconstriction and stroke after use of serotonergic drugs.
Topics: Antidepressive Agents; Brain; Cerebrovascular Circulation; Dietary Supplements; Drug and Narcotic Co | 2002 |
Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Cardiovascular Diseases; Cause | 2004 |
[Migraine has to be treated. Otherwise a stroke threatens].
Topics: Humans; Indoles; Migraine Disorders; Pyrrolidines; Risk Factors; Serotonin Receptor Agonists; Stroke | 2002 |