sumatriptan has been researched along with Reperfusion Injury in 4 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrated that sumatriptan has protective effects against mesenteric ischemia and the kynurenine inhibition is potentially involved in this process." | 8.31 | Low-dose sumatriptan improves the outcome of acute mesenteric ischemia in rats via downregulating kynurenine. ( Ala, M; Asl Soleimani, M; Dehpour, AR; Fallahpour Khoshdel, MR; Goudarzi, S; Mohammad Jafari, R; Sadrkhanloo, M, 2023) |
| "This study demonstrated that sumatriptan has protective effects against mesenteric ischemia and the kynurenine inhibition is potentially involved in this process." | 4.31 | Low-dose sumatriptan improves the outcome of acute mesenteric ischemia in rats via downregulating kynurenine. ( Ala, M; Asl Soleimani, M; Dehpour, AR; Fallahpour Khoshdel, MR; Goudarzi, S; Mohammad Jafari, R; Sadrkhanloo, M, 2023) |
| "Pre-treatment with sumatriptan decreased 5-hydroxytryptamine (5HT) level by 53%, and significantly decreased calcitonin gene-related peptide (CGRP) levels, lipid pereoxidation, neutrophil infiltration, and level of pro-inflammatory markers in the serum." | 1.56 | Involvement of 5-HT1B/1D receptors in the inflammatory response and oxidative stress in intestinal ischemia/reperfusion in rats. ( Abdollahi, A; Dehpour, AR; Gharishvandi, F; Mohammad Jafari, R; Pasalar, P; Shafaroodi, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ala, M | 1 |
| Fallahpour Khoshdel, MR | 1 |
| Mohammad Jafari, R | 3 |
| Sadrkhanloo, M | 1 |
| Goudarzi, S | 1 |
| Asl Soleimani, M | 1 |
| Dehpour, AR | 4 |
| Mobasheran, P | 1 |
| Rajai, N | 1 |
| Kohansal, P | 1 |
| Shafaroodi, H | 3 |
| Gharishvandi, F | 2 |
| Abdollahi, A | 2 |
| Pasalar, P | 2 |
4 other studies available for sumatriptan and Reperfusion Injury
| Article | Year |
|---|---|
Low-dose sumatriptan improves the outcome of acute mesenteric ischemia in rats via downregulating kynurenine.
Topics: Animals; Ischemia; Kynurenine; Mesenteric Ischemia; Rats; Reperfusion Injury; Sumatriptan; Tumor Nec | 2023 |
The effects of acute sumatriptan treatment on renal ischemia/reperfusion injury in rat and the possible involvement of nitric oxide.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Kidney; Male; Malondialdehyde; Nitric | 2020 |
Involvement of 5-HT1B/1D receptors in the inflammatory response and oxidative stress in intestinal ischemia/reperfusion in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Ileum; Inflammation; Intestinal Mucosa; Male; Mesenteric I | 2020 |
The protective effect of α7-nACh receptor and its interaction with 5-HT1B/1D receptors in acute intestinal ischemia-reperfusion injury in rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serot | 2022 |