sumatriptan has been researched along with Pregnancy in 39 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We prospectively compared pregnancy outcome after exposure to sumatriptan with that of disease-matched controls and nonteratogen controls." | 9.08 | Pregnancy outcome following first trimester exposure to sumatriptan. ( Brochu, J; Koren, G; Matsui, D; Pastuszak, A; Schick, B; Shuhaiber, S; Spivey, G, 1998) |
| " A systematic review of the medical literature was conducted to identify information regarding the safety of sumatriptan during pregnancy." | 8.82 | Safety of sumatriptan in pregnancy: a review of the data so far. ( Loder, E, 2003) |
| "To review the literature for treatment of migraine headaches with sumatriptan during pregnancy." | 8.82 | Treatment of migraine headaches with sumatriptan in pregnancy. ( Cross, LB; Eichner, SF; Hilaire, ML, 2004) |
| "To evaluate delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan." | 7.71 | Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan. ( Källén, B; Lygner, PE, 2001) |
| "Assessment of best available evidence for tolerability of sumatriptan after inadvertent exposure during pregnancy." | 7.71 | Evidence-based assessment of pregnancy outcome after sumatriptan exposure. ( Anderson, PO; Chambers, CD; Diamond, ML; Fox, AW; Spierings, EL, 2002) |
| "Perinatal and pregnancy outcome did not differ between patients who had and had not used sumatriptan after conception, at the resolution of these sample sizes." | 7.70 | Pregnancy and perinatal outcomes in migraineurs using sumatriptan: a prospective study. ( Davis, RL; Ephross, SA; Fox, AW; Gutterman, DL; O'Quinn, S; Williams, V, 1999) |
| "5% of fertile Danish women use sumatriptan, and the drug is also taken during pregnancy." | 7.70 | Pregnancy outcome following prescription for sumatriptan. ( Nielsen, GL; Olesen, C; Olsen, J; Sorensen, HT; Steffensen, FH, 2000) |
| " A systematic review of the medical literature was conducted to identify information regarding the safety of sumatriptan during pregnancy." | 4.82 | Safety of sumatriptan in pregnancy: a review of the data so far. ( Loder, E, 2003) |
| "To review the literature for treatment of migraine headaches with sumatriptan during pregnancy." | 4.82 | Treatment of migraine headaches with sumatriptan in pregnancy. ( Cross, LB; Eichner, SF; Hilaire, ML, 2004) |
| "Using the Marketscan database, the risk of major birth defects was ascertained in live-born infants whose birth mothers were exposed to sumatriptan, naratriptan, or sumatriptan/naproxen during pregnancy." | 3.88 | Use of existing electronic health care databases to evaluate medication safety in pregnancy: Triptan exposure in pregnancy as a case study. ( Bollinger, L; Cangialose, C; Chia, V; Mikol, DD; Xue, F; Yusuf, A, 2018) |
| "Accumulated data suggest that exposure to sumatriptan during pregnancy does not increase the risk of birth defects above the baseline rate." | 3.76 | Safety of triptans for migraine headaches during pregnancy and breastfeeding. ( Bozzo, P; Duong, S; Einarson, A; Nordeng, H, 2010) |
| " The mother used bisoprolol, naproxen and sumatriptan for migraine until the fifth postmenstrual week of pregnancy." | 3.72 | Bilateral cleft lip and palate, hypertelorism and hypoplastic toes. ( Kajantie, E; Somer, M, 2004) |
| "To evaluate delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan." | 3.71 | Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan. ( Källén, B; Lygner, PE, 2001) |
| "Assessment of best available evidence for tolerability of sumatriptan after inadvertent exposure during pregnancy." | 3.71 | Evidence-based assessment of pregnancy outcome after sumatriptan exposure. ( Anderson, PO; Chambers, CD; Diamond, ML; Fox, AW; Spierings, EL, 2002) |
| " The proportions of outcomes with birth defects are as follows: in the Acyclovir (antiviral medication) Pregnancy Registry (1984-1998) (19/581), 3." | 3.70 | Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment. ( Andrews, EB; Ephross, SA; Heffner, CR; Reiff-Eldridge, R; Tennis, PS; White, AD, 2000) |
| "Perinatal and pregnancy outcome did not differ between patients who had and had not used sumatriptan after conception, at the resolution of these sample sizes." | 3.70 | Pregnancy and perinatal outcomes in migraineurs using sumatriptan: a prospective study. ( Davis, RL; Ephross, SA; Fox, AW; Gutterman, DL; O'Quinn, S; Williams, V, 1999) |
| "5% of fertile Danish women use sumatriptan, and the drug is also taken during pregnancy." | 3.70 | Pregnancy outcome following prescription for sumatriptan. ( Nielsen, GL; Olesen, C; Olsen, J; Sorensen, HT; Steffensen, FH, 2000) |
| "Sumatriptan is a potent and selective serotonin1D receptor agonist, which can be administered orally and via the subcutaneous or intranasal route." | 2.39 | Acute treatment of migraine attacks. ( Ferrari, MD; Haan, J, 1995) |
| "Sumatriptan is a serotonin agonist that has been studied for the acute treatment of migraine and cluster headache." | 2.38 | Sumatriptan: a selective 5-hydroxytryptamine receptor agonist for the acute treatment of migraine. ( Fullerton, T; Gengo, FM, 1992) |
| "Allometric scaling is an empirical examination of the relationships between the pharmacokinetic parameters and size (usually body weight), but it can also involve brain weight for metabolized drug." | 1.30 | Mixed effect modeling of sumatriptan pharmacokinetics during drug development. I: Interspecies allometric scaling. ( Bye, A; Cosson, VF; Efthymiopoulos, C; Fuseau, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (33.33) | 18.2507 |
| 2000's | 16 (41.03) | 29.6817 |
| 2010's | 10 (25.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinshank, RL | 1 |
| Zgombick, JM | 1 |
| Macchi, MJ | 1 |
| Branchek, TA | 1 |
| Hartig, PR | 1 |
| Jarvis, S | 1 |
| Dassan, P | 1 |
| Piercy, CN | 1 |
| Yusuf, A | 1 |
| Chia, V | 1 |
| Xue, F | 1 |
| Mikol, DD | 1 |
| Bollinger, L | 1 |
| Cangialose, C | 1 |
| Cady, RK | 1 |
| Diener, HC | 1 |
| Bejan-Angoulvant, T | 1 |
| Beau-Salinas, F | 1 |
| Lengellé, C | 1 |
| Cissoko, H | 1 |
| Jonville-Béra, AP | 1 |
| Hultzsch, S | 1 |
| Schaefer, C | 1 |
| Duong, S | 1 |
| Bozzo, P | 1 |
| Nordeng, H | 1 |
| Einarson, A | 1 |
| Williams, SH | 1 |
| Kehr, HA | 1 |
| Loder, E | 1 |
| Nappi, G | 1 |
| Sandrini, G | 1 |
| Sances, G | 1 |
| Veselá, J | 1 |
| Rehák, P | 1 |
| Mihalik, J | 1 |
| Czikková, S | 1 |
| Pokorný, J | 1 |
| Koppel, J | 1 |
| Fox, AW | 4 |
| Kajantie, E | 1 |
| Somer, M | 1 |
| Sato, S | 1 |
| Shimizu, M | 1 |
| Endo, K | 1 |
| Homma, M | 1 |
| Yamamoto, T | 1 |
| Rousso, P | 1 |
| Hilaire, ML | 1 |
| Cross, LB | 1 |
| Eichner, SF | 1 |
| Gupta, S | 2 |
| Hanff, LM | 2 |
| Visser, W | 2 |
| Steegers, EA | 2 |
| Saxena, PR | 2 |
| Vulto, AG | 2 |
| MaassenVanDenBrink, A | 2 |
| Stallard, N | 1 |
| Barry, P | 1 |
| Ferrari, MD | 1 |
| Haan, J | 1 |
| Carp, H | 1 |
| Singh, PJ | 1 |
| Vadhera, R | 1 |
| Jayaram, A | 1 |
| Schenker, S | 1 |
| Yang, Y | 1 |
| Perez, A | 1 |
| Henderson, GI | 1 |
| Lee, MP | 1 |
| Freiherr Von Hornstein, W | 1 |
| Reich, A | 1 |
| Cosson, VF | 1 |
| Fuseau, E | 1 |
| Efthymiopoulos, C | 1 |
| Bye, A | 1 |
| Shuhaiber, S | 1 |
| Pastuszak, A | 1 |
| Schick, B | 1 |
| Matsui, D | 1 |
| Spivey, G | 1 |
| Brochu, J | 1 |
| Koren, G | 1 |
| Karlsson, C | 1 |
| Bodelsson, G | 1 |
| Bodelsson, M | 1 |
| Stjernquist, M | 1 |
| Sprigge, JS | 1 |
| Granier, I | 1 |
| Garcia, E | 1 |
| Geissler, A | 1 |
| Boespflug, MD | 1 |
| Durand-Gasselin, J | 1 |
| Reiff-Eldridge, R | 1 |
| Heffner, CR | 1 |
| Ephross, SA | 2 |
| Tennis, PS | 1 |
| White, AD | 1 |
| Andrews, EB | 1 |
| O'Quinn, S | 1 |
| Williams, V | 1 |
| Davis, RL | 1 |
| Gutterman, DL | 1 |
| Olesen, C | 2 |
| Steffensen, FH | 1 |
| Sorensen, HT | 1 |
| Nielsen, GL | 1 |
| Olsen, J | 2 |
| Källén, B | 1 |
| Lygner, PE | 1 |
| Chambers, CD | 1 |
| Anderson, PO | 1 |
| Diamond, ML | 1 |
| Spierings, EL | 1 |
| Fullerton, T | 1 |
| Gengo, FM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Sumatriptan and Naratriptan Pregnancy Registry[NCT01059604] | 868 participants (Actual) | Observational [Patient Registry] | 2001-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for sumatriptan and Pregnancy
| Article | Year |
|---|---|
Red flags and comfort signs for ominous secondary headaches.
Topics: Adult; Cooperative Behavior; Diagnosis, Differential; Diagnostic Imaging; Female; Headache Disorders | 2014 |
Migraine and pregnancy. Choice of treatment.
Topics: Abnormalities, Drug-Induced; Female; Fetus; Gestational Age; Humans; Migraine Disorders; Patient Sel | 2014 |
[Analgesic drugs during pregnancy].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa | 2016 |
An update in the treatment of neurologic disorders during pregnancy--focus on migraines and seizures.
Topics: Animals; Anticonvulsants; Female; Humans; Migraine Disorders; Nervous System Diseases; Pregnancy; Pr | 2012 |
Safety of sumatriptan in pregnancy: a review of the data so far.
Topics: Animals; Female; Humans; Migraine Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; | 2003 |
Tolerability of the triptans: clinical implications.
Topics: Brain; Cardiovascular System; Drug Interactions; Female; Fetus; Humans; Migraine Disorders; Pregnanc | 2003 |
Treatment of migraine headaches with sumatriptan in pregnancy.
Topics: Abnormalities, Drug-Induced; Clinical Trials as Topic; Female; Humans; Migraine Disorders; Pregnancy | 2004 |
Acute treatment of migraine attacks.
Topics: Adolescent; Adult; Analgesics; Child; Dihydroergotamine; Female; Humans; Male; Migraine Disorders; P | 1995 |
Sumatriptan: a selective 5-hydroxytryptamine receptor agonist for the acute treatment of migraine.
Topics: Clinical Trials as Topic; Drug Interactions; Female; Humans; Indoles; Migraine Disorders; Pregnancy; | 1992 |
1 trial available for sumatriptan and Pregnancy
| Article | Year |
|---|---|
Pregnancy outcome following first trimester exposure to sumatriptan.
Topics: Adult; Embryonic and Fetal Development; Female; Humans; Pregnancy; Pregnancy Outcome; Pregnancy Trim | 1998 |
29 other studies available for sumatriptan and Pregnancy
| Article | Year |
|---|---|
Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Cell Membrane; Cloning, Molecular; DNA Probes; Female; | 1992 |
Managing migraine in pregnancy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Female; Humans; Migraine with Aura; Pre | 2018 |
Use of existing electronic health care databases to evaluate medication safety in pregnancy: Triptan exposure in pregnancy as a case study.
Topics: Abnormalities, Drug-Induced; Administrative Claims, Healthcare; Adolescent; Adult; Databases, Factua | 2018 |
[Pregnant women can take triptans].
Topics: Congenital Abnormalities; Female; Humans; Naproxen; Piperidines; Pregnancy; Sumatriptan; Tryptamines | 2014 |
[Drugs news].
Topics: Abnormalities, Drug-Induced; Anti-Retroviral Agents; Azathioprine; Female; Humans; Infant, Newborn; | 2015 |
Triptans: beware of vasoconstrictive effects.
Topics: Adult; Female; Humans; Male; Migraine Disorders; Patient Selection; Pregnancy; Risk Assessment; Risk | 2014 |
Safety of triptans for migraine headaches during pregnancy and breastfeeding.
Topics: Breast Feeding; Female; Humans; Migraine Disorders; Piperidines; Pregnancy; Pregnancy Complications; | 2010 |
Expression of serotonin receptors in mouse oocytes and preimplantation embryos.
Topics: Animals; Blastocyst; Cells, Cultured; Culture Techniques; Female; Gene Expression Regulation, Develo | 2003 |
Revised estimates for probability of successful outcome of pregnancy after sumatriptan exposure.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Migraine Disorders; Pregnancy; Pregnan | 2004 |
Bilateral cleft lip and palate, hypertelorism and hypoplastic toes.
Topics: Abnormalities, Multiple; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bisop | 2004 |
[Postpartum cerebral angiopathy--a case report the vasculopathy associated with co-administration of two vasoconstrictives, methylergometrine maleate and sumatriptan].
Topics: Adult; Cerebrovascular Disorders; Female; Humans; Hypertension; Magnetic Resonance Imaging; Methyler | 2004 |
[Drug exposure during pregnancy: a differentiated approach].
Topics: Abnormalities, Drug-Induced; Abortion, Eugenic; Alcohol Drinking; Benzodiazepines; Drug Therapy; Fem | 2004 |
Revised estimates for probability of successful outcome of pregnancy after sumatriptan exposure.
Topics: Female; Humans; Pregnancy; Pregnancy Outcome; Risk Assessment; Serotonin Receptor Agonists; Sumatrip | 2004 |
Functional reactivity of 5-HT receptors in human umbilical cord and maternal subcutaneous fat arteries after normotensive or pre-eclamptic pregnancy.
Topics: Adult; Arteries; Blood Pressure; Data Interpretation, Statistical; Female; Fetus; Humans; Ketanserin | 2006 |
The effect of maternal ketanserin treatment on foetal 5-HT receptor function in umbilical cord artery of pre-eclamptic patients.
Topics: Adolescent; Adult; Antihypertensive Agents; Benzamides; Case-Control Studies; Dose-Response Relation | 2007 |
Another complication of the combined extradural-subarachnoid technique.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; | 1995 |
Effects of the serotonin-receptor agonist sumatriptan on postdural puncture headache: report of six cases.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Female; Headache; Humans; Male; Pregnancy; Spinal P | 1994 |
Sumatriptan (Imitrex) transport by the human placenta.
Topics: Biological Transport; Female; Humans; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Serot | 1995 |
[Limits of sumatriptan in the treatment of headache after dura mater puncture].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Patch, Epidural; Dura Mater; Female; Hea | 1996 |
Mixed effect modeling of sumatriptan pharmacokinetics during drug development. I: Interspecies allometric scaling.
Topics: Animals; Biological Availability; Dogs; Dose-Response Relationship, Drug; Drug Design; Female; Human | 1997 |
Characterization of 5-hydroxytryptamine receptors mediating circular smooth muscle contraction in the human umbilical artery.
Topics: Adolescent; Adult; Female; Humans; Ketanserin; Methiothepin; Muscle Contraction; Muscle, Smooth; Pre | 1999 |
The use of sumatriptan in the treatment of postdural puncture headache after accidental lumbar puncture complicated a blood patch procedure.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Blood Patch, Epidural; Female; Headache; Humans; | 1999 |
Postpartum cerebral angiopathy associated with the administration of sumatriptan and dihydroergotamine--a case report.
Topics: Adult; Cerebral Angiography; Cerebrovascular Disorders; Ergonovine; Female; Humans; Obstetric Labor | 1999 |
Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment.
Topics: Abnormalities, Drug-Induced; Acyclovir; Anticonvulsants; Antiviral Agents; Drug Industry; Epilepsy; | 2000 |
Pregnancy and perinatal outcomes in migraineurs using sumatriptan: a prospective study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Middle Aged; Migr | 1999 |
Pregnancy outcome following prescription for sumatriptan.
Topics: Adult; Drug Prescriptions; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Maternal Expos | 2000 |
Sumatriptan: what do we know about fetal risks?
Topics: Denmark; Female; Humans; Infant, Newborn; Infant, Premature; Maternal Exposure; Migraine Disorders; | 2001 |
Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan.
Topics: Adult; Congenital Abnormalities; Delivery, Obstetric; Female; Humans; Infant, Newborn; Middle Aged; | 2001 |
Evidence-based assessment of pregnancy outcome after sumatriptan exposure.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Evidence-Based Medicine; Female; Humans; Infant, | 2002 |