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sumatriptan and Pain, Chronic

sumatriptan has been researched along with Pain, Chronic in 5 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Research Excerpts

ExcerptRelevanceReference
"Ipsilateral, but not contralateral, pre-treatment (in μg/paw) with sumatriptan (10-300), methysergide (1-30) or dihydroergotamine (1-30) significantly prevented flinching behavior (at 1h) as well as secondary allodynia and hyperalgesia (at day 6) induced by formalin."3.79Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats. ( Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM, 2013)
"The prolongation of PGE2 hyperalgesia was also permanently reversed by intradermal injection of cordycepin, a protein translation inhibitor."1.43Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming. ( Araldi, D; Ferrari, LF; Levine, JD, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Tang, C1
Unekawa, M1
Kitagawa, S1
Takizawa, T1
Kayama, Y1
Nakahara, J1
Shibata, M1
Godínez-Chaparro, B1
López-Santillán, FJ1
Argüelles, CF1
Villalón, CM1
Granados-Soto, V1
Leone, M1
Proietti Cecchini, A1
Araldi, D1
Ferrari, LF1
Levine, JD1
Hultzsch, S1
Schaefer, C1

Reviews

1 review available for sumatriptan and Pain, Chronic

ArticleYear
[Analgesic drugs during pregnancy].
    Schmerz (Berlin, Germany), 2016, Volume: 30, Issue:6

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa

2016

Other Studies

4 other studies available for sumatriptan and Pain, Chronic

ArticleYear
Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant.
    Scientific reports, 2020, 07-10, Volume: 10, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cere

2020
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
    Life sciences, 2013, Jun-13, Volume: 92, Issue:22

    Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Dr

2013
Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache.
    Neurology, 2016, Jan-12, Volume: 86, Issue:2

    Topics: Adult; Aged; Chronic Pain; Cluster Headache; Drug Resistance; Female; Humans; Injections, Subcutaneo

2016
Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming.
    Pain, 2016, Volume: 157, Issue:8

    Topics: Animals; Chronic Pain; Female; Hyperalgesia; Male; Nociceptors; Pain Threshold; Rats; Rats, Sprague-

2016