sumatriptan has been researched along with Nerve Degeneration in 1 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using [3H]sumatriptan as a radioligand, 5-hydroxytryptamine (5-HT)1B receptors were examined in posterior striatum and midbrain post-mortem tissue sections of 12 patients who had died from representative degenerative movement disorders as compared to nine controls." | 3.70 | 5-HT1B receptor binding in degenerative movement disorders. ( Berciano, J; Castro, ME; Figols, J; Pascual, J; Pazos, A; Romón, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castro, ME | 1 |
| Pascual, J | 1 |
| Romón, T | 1 |
| Berciano, J | 1 |
| Figols, J | 1 |
| Pazos, A | 1 |
1 other study available for sumatriptan and Nerve Degeneration
| Article | Year |
|---|---|
5-HT1B receptor binding in degenerative movement disorders.
Topics: Aged; Aged, 80 and over; Corpus Striatum; Female; Humans; Huntington Disease; Male; Middle Aged; Mov | 1998 |