sumatriptan has been researched along with Muscle Contraction in 58 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with sumatriptan is able to restore impaired accommodation and to improve early satiety in patients with functional dyspepsia." | 2.41 | The physiology and the pathophysiology of the gastric accommodation reflex in man. ( Tack, J, 2000) |
| "Sumatriptan (Imigran) is a potent and highly selective 5-HT1 receptor agonist often used in treating acute migraine." | 1.42 | Effects of sumatriptan nasal spray (Imigran) on isolated rat's tracheal smooth muscle. ( Chang, YN; Cheng, LH; Chiu, FS; Chu, YH; Liu, SC; Wang, HW; Wu, PC, 2015) |
| "Sumatriptan can cause myocardial ischaemia and myocardial infarction." | 1.31 | Amplification of sumatriptan-induced contractions with phenylephrine, histamine and KCl in the isolated human mesenteric artery: in-vitro evidence for sumatriptan-induced mesenteric ischaemia. ( Gul, H; Yildiz, O, 2002) |
| "Eletriptan is a 5-HT(1B/1D) receptor agonist with proven efficacy in the acute treatment of migraine." | 1.31 | Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels. ( Avezaat, CJ; Bogers, AJ; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; van den Broek, RW, 2000) |
| "Several acutely acting antimigraine drugs, including ergotamine and sumatriptan, have the ability to constrict porcine arteriovenous anastomoses as well as the human isolated coronary artery." | 1.30 | Effects of avitriptan, a new 5-HT 1B/1D receptor agonist, in experimental models predictive of antimigraine activity and coronary side-effect potential. ( Bax, WA; De Vries, P; Heiligers, JP; Maassen vandenBrink, A; Saxena, PR; Wang, W; Yocca, FD, 1997) |
| "Naratriptan has high affinity for human recombinant 5HT1B and 5HT1D receptors (pKi = 8." | 1.30 | Naratriptan: biological profile in animal models relevant to migraine. ( Beattie, DT; Connor, HE; Feniuk, W; Humphrey, PP; North, PC; Oxford, AW; Saynor, DA, 1997) |
| "Frovatriptan was a potent contractile agent in isolated basilar artery with a -log mean effective concentration (EC50) value of 7." | 1.30 | Effects of the novel high-affinity 5-HT(1B/1D)-receptor ligand frovatriptan in human isolated basilar and coronary arteries. ( Hunter, J; Kaumann, AJ; King, FD; Parsons, AA; Raval, P; Smith, S; Tilford, N, 1998) |
| "Many acutely acting antimigraine drugs have the ability to constrict porcine arteriovenous anastomoses as well as the human isolated coronary artery." | 1.30 | BMS-181885, a 5-HT1B/1D receptor ligand, in experimental models predictive of antimigraine activity and coronary side-effect potential. ( Bax, WA; De Vries, P; Heiligers, JP; Maassen VanDenBrink, A; Saxena, PR; Yocca, FD, 1998) |
| " Both 8d,k were found to be well absorbed in the rat with oral bioavailabilities of 66% and 62%, respectively." | 1.29 | Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin- 2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor. ( Baker, R; Beer, MS; Castro, JL; Guiblin, AR; Hargreaves, RJ; Hobbs, SC; Jenkins, MR; Russell, MG; Scholey, K; Stanton, JA, 1994) |
| "Rizatriptan has shown efficacy as an anti-migraine agent in clinical trials." | 1.29 | 5-HT1D receptor agonists and human coronary artery reactivity in vitro: crossover comparisons of 5-HT and sumatriptan with rizatriptan and L-741,519. ( Boulanger, CM; Desta, B; Hill, RG; Longmore, J; Schofield, WN; Taylor, AA, 1996) |
| "Sumatriptan did not cause relaxation." | 1.28 | Sumatriptan contracts large coronary arteries of beagle dogs through 5-HT1-like receptors. ( Kaumann, AJ; Parsons, AA; Raval, P; Stutchbury, C, 1992) |
| "5." | 1.28 | Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery. ( Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (10.34) | 18.7374 |
| 1990's | 35 (60.34) | 18.2507 |
| 2000's | 12 (20.69) | 29.6817 |
| 2010's | 5 (8.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castro, JL | 1 |
| Baker, R | 1 |
| Guiblin, AR | 1 |
| Hobbs, SC | 1 |
| Jenkins, MR | 1 |
| Russell, MG | 1 |
| Beer, MS | 1 |
| Stanton, JA | 1 |
| Scholey, K | 1 |
| Hargreaves, RJ | 1 |
| Xu, YC | 1 |
| Johnson, KW | 2 |
| Phebus, LA | 1 |
| Cohen, M | 1 |
| Nelson, DL | 1 |
| Schenck, K | 2 |
| Walker, CD | 1 |
| Fritz, JE | 1 |
| Kaldor, SW | 1 |
| LeTourneau, ME | 1 |
| Murff, RE | 1 |
| Zgombick, JM | 1 |
| Calligaro, DO | 1 |
| Audia, JE | 1 |
| Schaus, JM | 1 |
| Choi, SK | 1 |
| Green, D | 1 |
| Ho, A | 1 |
| Klein, U | 1 |
| Marquess, D | 1 |
| Taylor, R | 1 |
| Turner, SD | 1 |
| Rubio-Beltrán, E | 1 |
| Labastida-Ramírez, A | 1 |
| Haanes, KA | 1 |
| van den Bogaerdt, A | 2 |
| Bogers, AJJC | 1 |
| Zanelli, E | 1 |
| Meeus, L | 1 |
| Danser, AHJ | 1 |
| Gralinski, MR | 1 |
| Senese, PB | 1 |
| Kovalchin, J | 1 |
| Villalón, CM | 3 |
| MaassenVanDenBrink, A | 4 |
| Amin, FM | 1 |
| Asghar, MS | 1 |
| Ravneberg, JW | 1 |
| de Koning, PJ | 1 |
| Larsson, HB | 1 |
| Olesen, J | 1 |
| Ashina, M | 1 |
| Chan, KY | 2 |
| Labruijere, S | 1 |
| Ramírez Rosas, MB | 1 |
| de Vries, R | 3 |
| Garrelds, IM | 1 |
| Danser, AH | 2 |
| Dirven, C | 1 |
| Cheng, LH | 1 |
| Wu, PC | 1 |
| Liu, SC | 1 |
| Chiu, FS | 1 |
| Chu, YH | 1 |
| Chang, YN | 1 |
| Wang, HW | 1 |
| Leijten, FP | 1 |
| Pfannkuche, HJ | 1 |
| van den Bogaerdt, AJ | 1 |
| Sekino, Y | 1 |
| Yamada, E | 1 |
| Sakai, E | 1 |
| Ohkubo, H | 1 |
| Higurashi, T | 1 |
| Iida, H | 1 |
| Endo, H | 1 |
| Takahashi, H | 1 |
| Koide, T | 1 |
| Sakamoto, Y | 1 |
| Nonaka, T | 1 |
| Gotoh, E | 1 |
| Maeda, S | 1 |
| Nakajima, A | 1 |
| Inamori, M | 1 |
| Gul, H | 1 |
| Yildiz, O | 3 |
| Jähnichen, S | 1 |
| Radtke, OA | 1 |
| Pertz, HH | 1 |
| Xue, L | 1 |
| Locke, GR | 1 |
| Camilleri, M | 1 |
| Schuurkes, JA | 1 |
| Meulemans, A | 1 |
| Coulie, BJ | 1 |
| Szurszewski, JH | 1 |
| Farrugia, G | 1 |
| Verheggen, R | 3 |
| Werner, I | 1 |
| Lücker, A | 1 |
| Brüss, M | 1 |
| Göthert, M | 1 |
| Kaumann, AJ | 6 |
| Tuncer, M | 3 |
| MacLean, MR | 1 |
| Clayton, RA | 1 |
| Hillis, SW | 1 |
| McIntyre, PD | 1 |
| Peacock, AJ | 1 |
| Templeton, AG | 1 |
| Beattie, DT | 2 |
| Connor, HE | 6 |
| Butler, A | 1 |
| Worton, SP | 1 |
| O'Shaughnessy, CT | 1 |
| Bax, WA | 4 |
| Renzenbrink, GJ | 1 |
| Van Heuven-Nolsen, D | 2 |
| Thijssen, EJ | 1 |
| Bos, E | 1 |
| Saxena, PR | 8 |
| Choppin, A | 1 |
| O'Connor, SE | 1 |
| Cushing, DJ | 1 |
| Baez, M | 1 |
| Kursar, JD | 1 |
| Cohen, ML | 2 |
| Cocks, TM | 2 |
| Kemp, BK | 2 |
| Pruneau, D | 1 |
| Angus, JA | 1 |
| Hamel, E | 2 |
| Fan, E | 1 |
| Linville, D | 1 |
| Ting, V | 1 |
| Villemure, JG | 1 |
| Chia, LS | 1 |
| Ferro, A | 1 |
| Longmore, J | 2 |
| Hill, RG | 2 |
| Brown, MJ | 1 |
| Carter, D | 1 |
| Champney, M | 1 |
| Hwang, B | 1 |
| Eglen, RM | 1 |
| Freudenthaler, S | 1 |
| Meyer-Dulheuer, F | 1 |
| Valentin, JP | 2 |
| Bonnafous, R | 2 |
| John, GW | 2 |
| Boulanger, CM | 1 |
| Desta, B | 1 |
| Schofield, WN | 1 |
| Taylor, AA | 1 |
| De Vries, P | 3 |
| Wang, W | 1 |
| Heiligers, JP | 3 |
| Maassen vandenBrink, A | 3 |
| Yocca, FD | 2 |
| Medhurst, AD | 1 |
| Brown, AM | 2 |
| Parsons, AA | 7 |
| Feniuk, W | 7 |
| North, PC | 1 |
| Oxford, AW | 2 |
| Saynor, DA | 1 |
| Humphrey, PP | 6 |
| Ellwood, AJ | 1 |
| Curtis, MJ | 1 |
| Dickenson, JM | 1 |
| Hill, SJ | 1 |
| Raval, P | 2 |
| Smith, S | 1 |
| Tilford, N | 1 |
| King, FD | 1 |
| Hunter, J | 1 |
| Hundeshagen, AG | 1 |
| Schindler, M | 1 |
| Karlsson, C | 1 |
| Bodelsson, G | 1 |
| Bodelsson, M | 1 |
| Stjernquist, M | 1 |
| Hemedah, M | 1 |
| Coupar, IM | 1 |
| Mitchelson, FJ | 1 |
| Willems, EW | 1 |
| Schenck, KW | 1 |
| Hemrick-Luecke, SH | 1 |
| Roon, KI | 1 |
| Maassen Van Den Brink, A | 1 |
| Ferrari, MD | 1 |
| Bouchelet, I | 1 |
| Case, B | 1 |
| Olivier, A | 1 |
| Reekers, M | 1 |
| Tack, J | 1 |
| van den Broek, RW | 1 |
| Bogers, AJ | 1 |
| Avezaat, CJ | 1 |
| Emre-Aydingöz, S | 1 |
| Kocaefe C, C | 1 |
| Sumner, MJ | 1 |
| McCormick, JD | 1 |
| Stutchbury, C | 1 |
| Motevalian, M | 1 |
| Whalley, ET | 4 |
| Tadipatri, S | 1 |
| Perren, MJ | 2 |
| Coates, LH | 1 |
| Butina, D | 1 |
1 review available for sumatriptan and Muscle Contraction
| Article | Year |
|---|---|
The physiology and the pathophysiology of the gastric accommodation reflex in man.
Topics: Adaptation, Physiological; Animals; Appetite; Dyspepsia; Gastric Emptying; Humans; Muscle Contractio | 2000 |
2 trials available for sumatriptan and Muscle Contraction
| Article | Year |
|---|---|
The effect of sumatriptan on cephalic arteries: A 3T MR-angiography study in healthy volunteers.
Topics: Adult; Cerebral Arteries; Female; Healthy Volunteers; Humans; Magnetic Resonance Angiography; Male; | 2013 |
Influence of sumatriptan on gastric accommodation and on antral contraction in healthy subjects assessed by ultrasonography.
Topics: Cross-Over Studies; Female; Gastric Emptying; Humans; Male; Muscle Contraction; Muscle, Smooth; Stom | 2012 |
55 other studies available for sumatriptan and Muscle Contraction
| Article | Year |
|---|---|
Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin- 2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor.
Topics: Animals; Drug Stability; In Vitro Techniques; Indoles; Muscle Contraction; Muscle, Smooth, Vascular; | 1994 |
N-[3-(2-Dimethylaminoethyl)-2-methyl-1H- indol-5-yl]-4-fluorobenzamide: a potent, selective, and orally active 5-HT(1F) receptor agonist potentially useful for migraine therapy.
Topics: Animals; Benzamides; Cell Line; Dura Mater; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Infla | 2001 |
Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide.
Topics: Animals; Benzamides; CHO Cells; Cricetinae; Cricetulus; Dimerization; In Vitro Techniques; Indoles; | 2008 |
Characterization of binding, functional activity, and contractile responses of the selective 5-HT
Topics: Animals; Benzamides; Binding, Competitive; Cell Membrane; CHO Cells; Coronary Vessels; Cricetulus; D | 2019 |
Cranioselectivity of sumatriptan revisited: pronounced contractions to sumatriptan in small human isolated coronary artery.
Topics: Adolescent; Adult; Aged; Biphenyl Compounds; Child; Colforsin; Coronary Vessels; Cyclic AMP; Dose-Re | 2014 |
Effects of sumatriptan nasal spray (Imigran) on isolated rat's tracheal smooth muscle.
Topics: Animals; Asthma; Disease Models, Animal; Electric Stimulation; Muscle Contraction; Muscle, Smooth; N | 2015 |
Functional characterization of contractions to tegaserod in human isolated proximal and distal coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Benzamides; C | 2009 |
Amplification of sumatriptan-induced contractions with phenylephrine, histamine and KCl in the isolated human mesenteric artery: in-vitro evidence for sumatriptan-induced mesenteric ischaemia.
Topics: Aged; Dose-Response Relationship, Drug; Female; Histamine; Humans; In Vitro Techniques; Ischemia; Ma | 2002 |
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation | 2004 |
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.
Topics: Animals; Atropine; Bethanechol; Buspirone; Gastric Fundus; Male; Mice; Muscle Contraction; Muscle, S | 2006 |
5-Hydroxytryptamine-induced contraction of human temporal arteries coexpressing 5-HT2A receptors and wild-type or variant (Phe124Cys) 5-HT1B receptors: increased contribution of 5-HT1B receptors to the total contractile amplitude in arteries from Phe124Cy
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Genetic Variation; Genotype; Heterozygote; Human | 2006 |
5-HT1-like and 5-HT2A receptors mediate 5-hydroxytryptamine-induced contraction of rabbit isolated mesenteric artery.
Topics: Adrenergic alpha-Agonists; Animals; Dinoprost; Female; In Vitro Techniques; Male; Mesenteric Arterie | 1995 |
5-HT1-receptor-mediated vasoconstriction in bovine isolated pulmonary arteries: influences of vascular endothelium and tone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Drug Interactions; Endothelium, Vascular; In | 1994 |
The pre- and postjunctional activity of CP-122,288, a conformationally restricted analogue of sumatriptan.
Topics: Animals; Basilar Artery; Blood Proteins; Capillary Permeability; Cell Line; Dogs; Dura Mater; Female | 1995 |
Sensory nerve-mediated relaxation of guinea-pig isolated pulmonary artery: prejunctional modulation by alpha 2-adrenoceptor agonists but not sumatriptan.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcitonin Gene-Related Peptide; Electric | 1993 |
5-HT receptors mediating contractions of the isolated human coronary artery.
Topics: Adolescent; Adult; Arteries; Blood Platelets; Child; Child, Preschool; Coronary Vessels; Dose-Respon | 1993 |
Amplification of responses to sumatriptan by various agonists in rabbit isolated iliac artery.
Topics: Angiotensin II; Animals; Drug Synergism; Female; Histamine; Iliac Artery; In Vitro Techniques; Male; | 1995 |
Presence of vasoconstrictor 5HT1-like receptors revealed by precontraction of rabbit isolated mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; In Vitro Techniques; Ma | 1995 |
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor.
Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coron | 1994 |
Comparison of contractile responses to 5-hydroxytryptamine and sumatriptan in human isolated coronary artery: synergy with the thromboxane A2-receptor agonist, U46619.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Coronary Vessels; Drug Synergism | 1993 |
Expression of mRNA for the serotonin 5-hydroxytryptamine1D beta receptor subtype in human and bovine cerebral arteries.
Topics: Animals; Base Sequence; Blotting, Northern; Cattle; Cerebral Arteries; Humans; Indoles; Migraine Dis | 1993 |
A comparison of the contractile effects of 5-hydroxytryptamine, sumatriptan and MK-462 on human coronary artery in vitro.
Topics: Coronary Vessels; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Muscle Contraction; | 1995 |
Effects of U46619 on contractions to 5-HT, sumatriptan and methysergide in canine coronary artery and saphenous vein in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Dogs; | 1995 |
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Inter | 1995 |
Participation of 5-HT1-like and 5-HT2A receptors in the contraction of human temporal artery by 5-hydroxytryptamine and related drugs.
Topics: Adult; Aged; Benzazepines; Collagenases; Endothelium, Vascular; Female; Headache; Humans; In Vitro T | 1996 |
Influence of the endothelium and nitric oxide on the contractile responses evoked by 5-HT1D receptor agonists in the rabbit isolated saphenous vein.
Topics: Animals; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascu | 1996 |
5-HT1D receptor agonists and human coronary artery reactivity in vitro: crossover comparisons of 5-HT and sumatriptan with rizatriptan and L-741,519.
Topics: Adult; Aged; Arteries; Coronary Vessels; Female; Humans; In Vitro Techniques; Male; Middle Aged; Mus | 1996 |
Effects of avitriptan, a new 5-HT 1B/1D receptor agonist, in experimental models predictive of antimigraine activity and coronary side-effect potential.
Topics: Animals; Arteriovenous Anastomosis; Blood Pressure; Carotid Arteries; Coronary Vessels; Head; Heart | 1997 |
Simultaneous measurement of [3H]noradrenaline release and neurogenic contraction under identical conditions, to determine the prejunctional inhibitory effects of SKF 99101H and BRL 56905 in dog saphenous vein.
Topics: Animals; Carbazoles; Dogs; Dose-Response Relationship, Drug; Female; Male; Muscle Contraction; Norep | 1997 |
Naratriptan: biological profile in animal models relevant to migraine.
Topics: Animals; Basilar Artery; Cerebrovascular Circulation; Disease Models, Animal; Dogs; Dose-Response Re | 1997 |
Involvement of 5-HT(1B/1D) and 5-HT2A receptors in 5-HT-induced contraction of endothelium-denuded rabbit epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Endot | 1997 |
Contractile responses evoked by dihydroergotamine, naratriptan and sumatriptan in the canine isolated coronary artery.
Topics: Animals; Coronary Vessels; Dihydroergotamine; Dogs; Endothelium, Vascular; Enzyme Inhibitors; In Vit | 1998 |
Human 5-HT1B receptor stimulated inositol phospholipid hydrolysis in CHO cells: synergy with Gq-coupled receptors.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; DNA, Complementary; Dose-Response Relationshi | 1998 |
Effects of the novel high-affinity 5-HT(1B/1D)-receptor ligand frovatriptan in human isolated basilar and coronary arteries.
Topics: Basilar Artery; Carbazoles; Coronary Circulation; Humans; In Vitro Techniques; Ligands; Muscle Contr | 1998 |
BMS-181885, a 5-HT1B/1D receptor ligand, in experimental models predictive of antimigraine activity and coronary side-effect potential.
Topics: Animals; Arteriovenous Anastomosis; Carotid Arteries; Coronary Vessels; Hemodynamics; Humans; In Vit | 1998 |
5-HT1B receptor-mediated contractions in human temporal artery: evidence from selective antagonists and 5-HT receptor mRNA expression.
Topics: Adolescent; Adult; Aged; Base Sequence; Biphenyl Compounds; DNA Primers; Female; Humans; In Vitro Te | 1998 |
Characterization of 5-hydroxytryptamine receptors mediating circular smooth muscle contraction in the human umbilical artery.
Topics: Adolescent; Adult; Female; Humans; Ketanserin; Methiothepin; Muscle Contraction; Muscle, Smooth; Pre | 1999 |
[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunum.
Topics: 5-Methoxytryptamine; Animals; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship | 1999 |
Investigation of the role of 5-HT1B and 5-HT1D receptors in the sumatriptan-induced constriction of porcine carotid arteriovenous anastomoses.
Topics: Animals; Arteriovenous Anastomosis; Biphenyl Compounds; Carotid Arteries; Dose-Response Relationship | 1999 |
5-Hydroxytryptamine(1A) receptor activation enhances norepinephrine release from nerves in the rabbit saphenous vein.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Fibers; Animals; Elect | 1999 |
Bovine isolated middle cerebral artery contractions to antimigraine drugs.
Topics: Animals; Cattle; In Vitro Techniques; Ketanserin; Middle Cerebral Artery; Muscle Contraction; Muscle | 1999 |
No contractile effect for 5-HT1D and 5-HT1F receptor agonists in human and bovine cerebral arteries: similarity with human coronary artery.
Topics: Animals; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techni | 2000 |
Human isolated coronary artery contraction to sumatriptan characterised by the selective 5-HT1B/1D receptor antagonist GR55562.
Topics: Benzamides; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Humans | 2000 |
Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels.
Topics: Aged; Blood Vessels; Brain; Cerebrovascular Circulation; Female; Humans; Indoles; Kinetics; Male; Mi | 2000 |
Calcium-antagonistic activity of sumatriptan in the rat anococcygeus muscle.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Cell Membrane; Cyclic AMP; Dose-Response Rela | 2002 |
Studies on the mechanism of 5-HT1 receptor-induced smooth muscle contraction in dog saphenous vein.
Topics: Adenylyl Cyclase Inhibitors; Animals; Brain Chemistry; Calcium; Colforsin; Cyclic AMP; Dinoprostone; | 1992 |
Sumatriptan contracts large coronary arteries of beagle dogs through 5-HT1-like receptors.
Topics: Animals; Arteries; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Indol | 1992 |
Contractile effects of 8-hydroxy-2-(di-n-propylamino)tetralin and flesinoxan in human isolated basilar artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Antihypertensive Agents; Basilar Artery; Humans; In Vitro Te | 1991 |
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)te | 1991 |
5-HT1-like receptors mediate 5-hydroxytryptamine-induced contraction of human isolated basilar artery.
Topics: Basilar Artery; Female; Humans; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smoo | 1989 |
5-Hydroxytryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Child; Coronary Vessels; | 1989 |
GR43175 does not share the complex pharmacology of the ergots.
Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Ergotamines; Female; Indoles; Male; | 1989 |
Characterization of the 5-hydroxytryptamine receptor which mediates contraction of the human isolated basilar artery.
Topics: Basilar Artery; Female; Humans; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smoo | 1989 |
Evidence for the presence of 5-HT1-like receptors in rabbit isolated basilar arteries.
Topics: Animals; Basilar Artery; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Indoles; Male; Muscl | 1989 |
GR43175, a selective agonist for the 5-HT1-like receptor in dog isolated saphenous vein.
Topics: Animals; Cats; Dogs; Female; In Vitro Techniques; Indoles; Male; Methiothepin; Muscle Contraction; M | 1988 |