sumatriptan has been researched along with Heart Disease, Ischemic in 12 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sumatriptan, a medication usually prescribed for acute migraine and cluster headaches has been documented as potentially causing coronary vasospasm, thereby leading to MI." | 3.96 | Vasospasm induced myocardial ischaemia secondary to sumatriptan use. ( Ojha, U; Okonkwo, K, 2020) |
| " Forty-five patients (88%) reported at least one adverse event and 23 (45%) experienced pressure, tightness, and/or pain in the chest, neck, and/or throat after administration of avitriptan." | 2.69 | Safety trial with the 5HT1B/1D agonist avitriptan (BMS-180048) in patients with migraine who have experienced pressure, tightness, and/or pain in the chest, neck, and/or throat following sumatriptan. ( Dahlöf, CG; Falk, L; Lewis, CP; Risenfors, M, 1998) |
| "Part 1 discusses the risks for Torsade de Pointes, vasospasm, and ischemia, with a review and discussion of case reports of triptan-associated cardiovascular events in migraineurs with and without CAD risk factors or documented CAD; of the epidemiology and studies of triptans, vasospasm, and cardiovascular morbidity; and of the relationship of variant angina, migraine, and vasospastic disease." | 2.49 | QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, and headache medications. Part 1: review of serotonergic cardiac adverse events with a triptan case. ( Cho, L; Stillman, MJ; Tepper, DE; Tepper, S, 2013) |
| "Migraine is a common disorder with a prevalence of 9-10% in Hungary." | 2.41 | [Treatment of migraine in patients with hypertension and ischemic heart disease]. ( Csiba, L; Ficzere, A, 2002) |
| "Their clinical diagnoses were migraine with aura, migraine without aura, cluster headache, and others." | 1.31 | Evidence against strong correlation between chest symptoms and ischemic coronary changes after subcutaneous sumatriptan injection. ( Endo, M; Igarashi, H; Sakai, F; Suzuki, N; Tomita, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Okonkwo, K | 1 |
| Ojha, U | 1 |
| Lynch, JJ | 1 |
| Stump, GL | 1 |
| Kane, SA | 1 |
| Regan, CP | 1 |
| Stillman, MJ | 1 |
| Tepper, S | 1 |
| Tepper, DE | 1 |
| Cho, L | 1 |
| Ficzere, A | 1 |
| Csiba, L | 1 |
| Hirata, K | 1 |
| Tomita, M | 1 |
| Suzuki, N | 1 |
| Igarashi, H | 1 |
| Endo, M | 1 |
| Sakai, F | 1 |
| Kaumann, AJ | 1 |
| Frenken, M | 1 |
| Posival, H | 1 |
| Brown, AM | 1 |
| Hillis, WS | 1 |
| MacIntyre, PD | 1 |
| Ferrari, MD | 2 |
| Haan, J | 1 |
| Visser, WH | 1 |
| Saxena, PR | 2 |
| Bax, WA | 2 |
| Mulder, LJ | 1 |
| Dahlöf, CG | 2 |
| Mathew, N | 1 |
| Falk, L | 1 |
| Risenfors, M | 1 |
| Lewis, CP | 1 |
| Maassen VanDenBrink, A | 1 |
| Ramrattan, NN | 1 |
4 reviews available for sumatriptan and Heart Disease, Ischemic
| Article | Year |
|---|---|
QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, and headache medications. Part 1: review of serotonergic cardiac adverse events with a triptan case.
Topics: Coronary Vasospasm; Electrocardiography; Female; Humans; Middle Aged; Migraine Disorders; Myocardial | 2013 |
[Treatment of migraine in patients with hypertension and ischemic heart disease].
Topics: Adjuvants, Pharmaceutic; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbazol | 2002 |
[Sumatriptan in clinical practice].
Topics: Adolescent; Adult; Child; Cluster Headache; Humans; Indoles; Migraine Disorders; Myocardial Ischemia | 1993 |
Cardiovascular safety of 5HT1B/1D agonists--is there a cause for concern?
Topics: Aged; Chest Pain; Contraindications; Coronary Circulation; Death, Sudden, Cardiac; Diagnosis, Differ | 1998 |
1 trial available for sumatriptan and Heart Disease, Ischemic
| Article | Year |
|---|---|
Safety trial with the 5HT1B/1D agonist avitriptan (BMS-180048) in patients with migraine who have experienced pressure, tightness, and/or pain in the chest, neck, and/or throat following sumatriptan.
Topics: Adult; Chest Pain; Diagnosis, Differential; Electrocardiography; Electrocardiography, Ambulatory; Fe | 1998 |
7 other studies available for sumatriptan and Heart Disease, Ischemic
| Article | Year |
|---|---|
Vasospasm induced myocardial ischaemia secondary to sumatriptan use.
Topics: Coronary Angiography; Coronary Vasospasm; Electrocardiography; Humans; Male; Middle Aged; Migraine D | 2020 |
The prototype serotonin 5-HT 1B/1D agonist sumatriptan increases the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis.
Topics: Animals; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Stenosis; Disease Models, Animal | 2009 |
Sumatriptan-induced chest symptoms in Japanese.
Topics: Chest Pain; Humans; Japan; Migraine Disorders; Myocardial Ischemia; Serotonin Receptor Agonists; Sum | 2002 |
Evidence against strong correlation between chest symptoms and ischemic coronary changes after subcutaneous sumatriptan injection.
Topics: Adolescent; Adult; Chest Pain; Female; Humans; Injections, Subcutaneous; Japan; Male; Middle Aged; M | 2002 |
Variable participation of 5-HT1-like receptors and 5-HT2 receptors in serotonin-induced contraction of human isolated coronary arteries. 5-HT1-like receptors resemble cloned 5-HT1D beta receptors.
Topics: Adult; Arteriosclerosis; Binding, Competitive; Cardiomyopathy, Dilated; Cloning, Molecular; Coronary | 1994 |
Sumatriptan and chest pain.
Topics: Chest Pain; Electrocardiography; Hemodynamics; Humans; Indoles; Myocardial Infarction; Myocardial Is | 1993 |
Human isolated coronary artery contraction to sumatriptan: a post hoc analysis.
Topics: Adult; Aged; Cause of Death; Chest Pain; Contraindications; Coronary Disease; Coronary Vessels; Dise | 1999 |