sumatriptan has been researched along with Headache in 149 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-treatment with ketorolac was more effective in attenuating PACAP38-induced headache compared to sumatriptan." | 9.34 | Investigation of sumatriptan and ketorolac trometamol in the human experimental model of headache. ( Al-Karagholi, MA; Amin, FM; Arngrim, N; Ashina, M; Ghanizada, H; Larsson, HBW; Metcalf-Clausen, M; Mørch-Rasmussen, M, 2020) |
| "Cilostazol induced a mild to moderate headache in all but 3 participants (Range 0-7 on Numerical Rating Scale)." | 9.27 | Pre-treatment with sumatriptan for cilostazol induced headache in healthy volunteers. ( Falkenberg, K; Olesen, J, 2018) |
| "Use of sumatriptan improved the quality of recovery as measured by the QoR-40 and reduction of headache at 24 h after surgery." | 9.22 | Sumatriptan improves postoperative quality of recovery and reduces postcraniotomy headache after cranial nerve decompression. ( Bailey, T; Li, L; Manninen, PH; Tymianski, M; Venkatraghavan, L, 2016) |
| " We randomized patients to either naproxen 500 mg or sumatriptan 100 mg for headache recurrence after ED discharge." | 9.14 | Treating headache recurrence after emergency department discharge: a randomized controlled trial of naproxen versus sumatriptan. ( Bijur, PE; Dua, N; Esses, D; Friedman, BW; Gallagher, EJ; Heins, A; Hochberg, M; Lipton, RB; Sasso, P; Solorzano, C; Xia, S, 2010) |
| "To determine the efficacy of sumatriptan in the management of patients presenting for an epidural blood patch for the management of postdural puncture headache." | 9.09 | Sumatriptan in patients with postdural puncture headache. ( Connelly, NR; Gibson, CS; Parker, RK; Rahimi, A, 2000) |
| " Nitroglycerin (NTG) administration commonly causes a headache with some features similar to those of a migraine." | 9.09 | The pharmacodynamics of sumatriptan in nitroglycerin-induced headache. ( Forrest, A; Fullerton, T; Gengo, FM; Komorowski-Swiatek, D, 1999) |
| "Eight female patients (ages 34-45 years old) participated in the trial and experienced a total of 13 post-ECT headaches, which were treated with intranasal sumatriptan." | 9.09 | Intranasal sumatriptan in post-ECT headache: results of an open-label trial. ( Beale, MD; Burns, C; DeVane, CL; Folk, J; Kellner, CH; Liston, HL; Markowitz, JS, 2001) |
| "Sumatriptan is a selective 5-hydroxytryptamine1d (5-HT1d)-receptor agonist, highly effective in the short-term treatment of migraine headaches." | 9.08 | Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model. ( Eichler, HG; Findl, O; Graselli, U; Krejcy, K; Schmetterer, L; Singer, EA; Wolzt, M, 1996) |
| "In a pilot study (5 patients) we investigated the effects of subcutaneous sumatriptan, a 5-HT1-like receptor agonist, on headache experienced during the withdrawal period of drug-induced headache." | 9.07 | Subcutaneous sumatriptan in the treatment of headache during withdrawal from drug-induced headache. ( Dichgans, J; Diener, HC; Haab, J; Peters, C; Pilgrim, A; Ried, S, 1991) |
| "Subcutaneous treatment of chronic tension-type headache with 2 mg and 4 mg sumatriptan, a selective 5-hydroxytryptamine1-like receptor agonist, was compared with placebo in a double-blind crossover study of 36 patients." | 9.07 | The 5-HT1-like agonist sumatriptan has a significant effect in chronic tension-type headache. ( Brennum, J; Kjeldsen, M; Olesen, J, 1992) |
| "For more than a century, aspirin has been used for the acute treatment of primary headaches." | 8.90 | Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches. ( D'Alonzo, L; Lecchi, M; Martelletti, P; Negro, A, 2014) |
| "In this study, we determine the effectiveness and adverse effects of sumatriptan when used in the emergency department (ED) as a first-line treatment for benign undifferentiated headaches, and determine if the International Headache Society (IHS) classification of migraine, probable migraine, or tension-type headache has any effect on the effectiveness of the treatment." | 7.74 | Sumatriptan for the treatment of undifferentiated primary headaches in the ED. ( Biros, M; Miner, JR; Moore, J; Smith, SW, 2007) |
| "To study the efficacy and practicality of treating headache in professional footballers with intranasal sumatriptan." | 7.73 | Open label study of intranasal sumatriptan (Imigran) for footballer's headache. ( Heywood, J; McCrory, P; Ugoni, A, 2005) |
| "To document the relationship between the 5-HT receptor agonist sumatriptan and a change in the nature of cluster headache in four cases." | 7.70 | Alteration in nature of cluster headache during subcutaneous administration of sumatriptan. ( Hering-Hanit, R, 2000) |
| "The use of sumatriptan for the treatment of migraine and cluster headache is well established." | 7.70 | Sumatriptan for headache caused by head and neck cancer. ( Manfredi, PL; Payne, R; Shenoy, S, 2000) |
| "Headache recurrence (HR) is the major limitation of sumatriptan in the acute treatment of migraine attacks." | 7.69 | Risk factors for headache recurrence after sumatriptan: a study in 366 migraine patients. ( de Vriend, RH; Ferrari, MD; Jaspers, NM; Visser, WH, 1996) |
| "We describe the case report of a migraine sufferer who developed ergotamine-induced headache and subsequently replaced ergotamine with daily sumatriptan (100 mg p." | 7.69 | Ergotamine-induced headache can be sustained by sumatriptan daily intake. ( Argentino, C; Catarci, T; Cerbo, R; Fiacco, F; Sette, G, 1994) |
| "Seven patients with posttraumatic headaches refractory to other medical treatment were treated with sumatriptan, 6 mg subcutaneously, at the peak of a headache." | 7.68 | Subcutaneous sumatriptan in the treatment of acute episodes of posttraumatic headache. ( Gawel, MJ; Jacobs, H; Rothbart, P, 1993) |
| "Headache is a common presenting condition for patients seen in the pediatric emergency department (ED)." | 7.01 | Sumatriptan as a First-Line Treatment for Headache in the Pediatric Emergency Department. ( Barry, D; Blume, H; Hartford, EA; Hauser Chatterjee, J; Law, E, 2023) |
| "Headache was rated on a 10 points scale." | 6.68 | Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs. ( Iversen, HK; Olesen, J, 1996) |
| "Our data suggest that sumatriptan reduces central sensitization (secondary hyperalgesia) without modulating peripheral sensitization (primary hyperalgesia) in a human pain model of capsaicin-induced sensitization." | 5.51 | Sumatriptan prevents central sensitization specifically in the trigeminal dermatome in humans. ( Basedau, H; Jürgens, T; May, A; Ortlieb, L; Peng, KP, 2022) |
| " Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need." | 5.41 | The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials. ( Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW, 2023) |
| "Sumatriptan was developed as an agent for the treatment of acute migraine." | 5.35 | Subcutaneous sumatriptan relieved migraine-like headache in two adolescents with aseptic meningitis. ( Alapati, D; Khanna, S; Pallimalli, SL; Prokhorov, S, 2008) |
| "Post-treatment with ketorolac was more effective in attenuating PACAP38-induced headache compared to sumatriptan." | 5.34 | Investigation of sumatriptan and ketorolac trometamol in the human experimental model of headache. ( Al-Karagholi, MA; Amin, FM; Arngrim, N; Ashina, M; Ghanizada, H; Larsson, HBW; Metcalf-Clausen, M; Mørch-Rasmussen, M, 2020) |
| "To investigate the effect of levcromakalim on the cranial arteries and to explore the possible relationship between the middle meningeal artery (MMA) dilation and headache." | 5.30 | Levcromakalim, an Adenosine Triphosphate-Sensitive Potassium Channel Opener, Dilates Extracerebral but not Cerebral Arteries. ( Al-Karagholi, MA; Amin, FM; Ashina, M; Ghanizada, H; Hansen, JM; Larsson, HBW; Olesen, J; Skovgaard, LT, 2019) |
| "Cilostazol induced a mild to moderate headache in all but 3 participants (Range 0-7 on Numerical Rating Scale)." | 5.27 | Pre-treatment with sumatriptan for cilostazol induced headache in healthy volunteers. ( Falkenberg, K; Olesen, J, 2018) |
| "Use of sumatriptan improved the quality of recovery as measured by the QoR-40 and reduction of headache at 24 h after surgery." | 5.22 | Sumatriptan improves postoperative quality of recovery and reduces postcraniotomy headache after cranial nerve decompression. ( Bailey, T; Li, L; Manninen, PH; Tymianski, M; Venkatraghavan, L, 2016) |
| " At the time of discharge, for patients randomized to comprehensive care, the research team reinforced their diagnosis, shared a migraine education presentation from the National Library of Medicine, provided them with six tablets of sumatriptan 100 mg and 14 tablets of naproxen 500 mg, and if they wished, provided them with an expedited free appointment to the institution's headache clinic." | 5.16 | A randomized controlled trial of a comprehensive migraine intervention prior to discharge from an emergency department. ( Adewumni, V; Bijur, PE; Campbell, CM; Esses, D; Friedman, BW; John Gallagher, E; Lipton, RB; Norton, J; Solomon, S; Solorzano, C, 2012) |
| " We randomized patients to either naproxen 500 mg or sumatriptan 100 mg for headache recurrence after ED discharge." | 5.14 | Treating headache recurrence after emergency department discharge: a randomized controlled trial of naproxen versus sumatriptan. ( Bijur, PE; Dua, N; Esses, D; Friedman, BW; Gallagher, EJ; Heins, A; Hochberg, M; Lipton, RB; Sasso, P; Solorzano, C; Xia, S, 2010) |
| "To determine the impact of sumatriptan prophylaxis on acute mountain sickness (AMS) and altitude headache development within 24 hours of ascent, we designed a double-blind, randomized, clinical trial." | 5.12 | Sumatriptan for prevention of acute mountain sickness: randomized clinical trial. ( Gorouhi, F; Jafarian, S; Lotfi, J; Salimi, S, 2007) |
| "Eight female patients (ages 34-45 years old) participated in the trial and experienced a total of 13 post-ECT headaches, which were treated with intranasal sumatriptan." | 5.09 | Intranasal sumatriptan in post-ECT headache: results of an open-label trial. ( Beale, MD; Burns, C; DeVane, CL; Folk, J; Kellner, CH; Liston, HL; Markowitz, JS, 2001) |
| "To determine the efficacy of sumatriptan in the management of patients presenting for an epidural blood patch for the management of postdural puncture headache." | 5.09 | Sumatriptan in patients with postdural puncture headache. ( Connelly, NR; Gibson, CS; Parker, RK; Rahimi, A, 2000) |
| " Nitroglycerin (NTG) administration commonly causes a headache with some features similar to those of a migraine." | 5.09 | The pharmacodynamics of sumatriptan in nitroglycerin-induced headache. ( Forrest, A; Fullerton, T; Gengo, FM; Komorowski-Swiatek, D, 1999) |
| "Sumatriptan is a selective 5-hydroxytryptamine1d (5-HT1d)-receptor agonist, highly effective in the short-term treatment of migraine headaches." | 5.08 | Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model. ( Eichler, HG; Findl, O; Graselli, U; Krejcy, K; Schmetterer, L; Singer, EA; Wolzt, M, 1996) |
| "In a pilot study (5 patients) we investigated the effects of subcutaneous sumatriptan, a 5-HT1-like receptor agonist, on headache experienced during the withdrawal period of drug-induced headache." | 5.07 | Subcutaneous sumatriptan in the treatment of headache during withdrawal from drug-induced headache. ( Dichgans, J; Diener, HC; Haab, J; Peters, C; Pilgrim, A; Ried, S, 1991) |
| "Subcutaneous treatment of chronic tension-type headache with 2 mg and 4 mg sumatriptan, a selective 5-hydroxytryptamine1-like receptor agonist, was compared with placebo in a double-blind crossover study of 36 patients." | 5.07 | The 5-HT1-like agonist sumatriptan has a significant effect in chronic tension-type headache. ( Brennum, J; Kjeldsen, M; Olesen, J, 1992) |
| " There is high confidence that adolescents receiving oral sumatriptan/naproxen and zolmitriptan nasal spray are more likely to be headache-free at 2 hours than those receiving placebo." | 5.01 | Practice guideline update summary: Acute treatment of migraine in children and adolescents: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society. ( Billinghurst, L; Gersz, EM; Gloss, D; Hershey, AD; Holler-Managan, Y; Leininger, E; Licking, N; Mack, K; Oskoui, M; Potrebic, S; Pringsheim, T; Sowell, M; Victorio, MC; Yonker, M; Zanitsch, H, 2019) |
| "For more than a century, aspirin has been used for the acute treatment of primary headaches." | 4.90 | Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches. ( D'Alonzo, L; Lecchi, M; Martelletti, P; Negro, A, 2014) |
| " Attack treatment in cluster headache is based on sumatriptan and oxygen." | 4.82 | [Treatment of cluster headache]. ( Fabre, N, 2005) |
| " For the acute treatment of migraine attacks or tension-type headache, ibuprofen (10 mg per kg body weight) or acetaminophen (15 mg per kg body weight) are recommended with highest evidence, intranasal sumatriptan (10 to 20 mg) can be given as second choice." | 4.81 | [Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. ( Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M, 2002) |
| "Headache care specialists agree that the introduction of sumatriptan constitutes a major advance in headache therapy, but they differ about whether other triptans offer clinically significant advantages over sumatriptan." | 4.81 | Triptans: do they differ? ( Salonen, R; Scott, A, 2002) |
| " In placebo-controlled clinical trials, sumatriptan, administered subcutaneously, orally, intranasally or rectally was significantly more effective than placebo in relieving migraine headache and in producing relief or resolution of other symptoms associated with migraine, including nausea, photophobia and phonophobia." | 4.81 | Sumatriptan: pharmacological basis and clinical results. ( Dahlöf, CG, 2001) |
| "To assess the reimbursement options and accessibility of three effective medicines for cluster headache (CH) (subcutaneous sumatriptan, oxygen, and zolmitriptan spray) across the European Union (EU)." | 3.96 | Availability of Effective Evidence-Based Symptomatic Treatments for Cluster Headache in the EU Countries-A Survey of the European Headache Alliance and European Headache Federation. ( De La Torre, ER; Di Lorenzo, C; Mitsikostas, D; Palmaro, A; Rossi, P, 2020) |
| "The present study showed that repeated IS stimulations induced long-lasting allodynia, increased BBB permeability, and upregulated VEGF expression, all of which could be attenuated by early sumatriptan treatment." | 3.88 | Recurrent Headache Increases Blood-Brain Barrier Permeability and VEGF Expression in Rats. ( Chen, L; Mi, X; Qin, G; Ran, L, 2018) |
| "In this study, we determine the effectiveness and adverse effects of sumatriptan when used in the emergency department (ED) as a first-line treatment for benign undifferentiated headaches, and determine if the International Headache Society (IHS) classification of migraine, probable migraine, or tension-type headache has any effect on the effectiveness of the treatment." | 3.74 | Sumatriptan for the treatment of undifferentiated primary headaches in the ED. ( Biros, M; Miner, JR; Moore, J; Smith, SW, 2007) |
| "To study the efficacy and practicality of treating headache in professional footballers with intranasal sumatriptan." | 3.73 | Open label study of intranasal sumatriptan (Imigran) for footballer's headache. ( Heywood, J; McCrory, P; Ugoni, A, 2005) |
| " The objective of this investigation was to develop a disease model to predict measures of headache in randomized placebo-controlled clinical trials investigating oral sumatriptan as a paradigm compound." | 3.73 | Prediction of headache response in migraine treatment. ( Danhof, M; Della Pasqua, OE; Maas, HJ, 2006) |
| " Sumatriptan, an agonist of 5-HT1-like receptors, has proven effective in the treatment of cluster headache attacks." | 3.70 | Chronic paroxysmal hemicrania and hemicrania continua: lack of efficacy of sumatriptan. ( Antonaci, F; Caminero, AB; Pareja, JA; Sjaastad, O, 1998) |
| "The use of sumatriptan for the treatment of migraine and cluster headache is well established." | 3.70 | Sumatriptan for headache caused by head and neck cancer. ( Manfredi, PL; Payne, R; Shenoy, S, 2000) |
| "To document the relationship between the 5-HT receptor agonist sumatriptan and a change in the nature of cluster headache in four cases." | 3.70 | Alteration in nature of cluster headache during subcutaneous administration of sumatriptan. ( Hering-Hanit, R, 2000) |
| "It is concluded that MD is associated with headache that can be handicapping, and tricyclic antidepressants with pain alleviating medication is often needed to treat the headache in MD whereas sumatriptan did not alleviate the headache of the non-migraine patients." | 3.70 | Headache in Meniere's disease. ( Eklund, S, 1999) |
| "We describe the case report of a migraine sufferer who developed ergotamine-induced headache and subsequently replaced ergotamine with daily sumatriptan (100 mg p." | 3.69 | Ergotamine-induced headache can be sustained by sumatriptan daily intake. ( Argentino, C; Catarci, T; Cerbo, R; Fiacco, F; Sette, G, 1994) |
| "Headache recurrence (HR) is the major limitation of sumatriptan in the acute treatment of migraine attacks." | 3.69 | Risk factors for headache recurrence after sumatriptan: a study in 366 migraine patients. ( de Vriend, RH; Ferrari, MD; Jaspers, NM; Visser, WH, 1996) |
| "Seven patients with posttraumatic headaches refractory to other medical treatment were treated with sumatriptan, 6 mg subcutaneously, at the peak of a headache." | 3.68 | Subcutaneous sumatriptan in the treatment of acute episodes of posttraumatic headache. ( Gawel, MJ; Jacobs, H; Rothbart, P, 1993) |
| "Headache is a common presenting condition for patients seen in the pediatric emergency department (ED)." | 3.01 | Sumatriptan as a First-Line Treatment for Headache in the Pediatric Emergency Department. ( Barry, D; Blume, H; Hartford, EA; Hauser Chatterjee, J; Law, E, 2023) |
| "The origin of migraine pain is unknown but possibly implicates the dura mater, which is pain sensitive in proximity to the meningeal arteries." | 2.90 | Meningeal contribution to migraine pain: a magnetic resonance angiography study. ( Amin, FM; Ashina, M; Christensen, CE; de Koning, PJH; Ghanizada, H; Khan, S; Larsson, HBW; Olinger, ACR; Younis, S, 2019) |
| "Headache is one of the most common symptoms of COVID." | 2.82 | Post-COVID Headache: A Literature Review. ( Chhabra, N; Grill, MF; Singh, RBH, 2022) |
| "Sumatriptan injectable was also effective for headache relief and was found to be better than nasal spray zolmitriptan (OR 2." | 2.82 | Network meta-analysis of therapies for cluster headache: Effects of acute therapies for episodic and chronic cluster. ( Christie, S; Hutton, B; Medrea, I; Tepper, SJ; Thavorn, K, 2022) |
| "PACAP38-induced headache is associated with prolonged dilatation of the MMA but not of the MCA." | 2.77 | Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers. ( Amin, FM; Asghar, MS; Ashina, M; de Koning, PJ; Guo, S; Hansen, AE; Hougaard, A; Larsson, HB; Olesen, J; Schytz, HW; van der Geest, RJ, 2012) |
| "In conclusion, it is reassuring for migraineurs that it is worthwhile taking their medication in an appropriate formulation even if they have not been able to do so early in the course of the attack." | 2.72 | Subcutaneous sumatriptan provides symptomatic relief at any pain intensity or time during the migraine attack. ( Dahlöf, C; Linde, M; Mellberg, A, 2006) |
| "Data from migraineurs enrolled in the active arms of a randomized, double-blind, parallel group, placebo-controlled, clinical trial were analysed." | 2.72 | Does earlier headache response equate to earlier return to functioning in patients suffering from migraine? ( Mullins, CD; Pradel, FG; Subedi, P; Varghese, AA; Weis, KA, 2006) |
| "Frovatriptan treatment produced an adverse events profile similar to that of placebo, and in a direct comparison study was better tolerated than sumatriptan 100 mg." | 2.70 | Tolerability and safety of frovatriptan with short- and long-term use for treatment of migraine and in comparison with sumatriptan. ( Géraud, G; Keywood, C; Spierings, EL, 2002) |
| "Headache was rated on a 10 points scale." | 2.68 | Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs. ( Iversen, HK; Olesen, J, 1996) |
| "Sumatriptan was generally well tolerated, the most frequently reported event being taste disturbance." | 2.67 | Intranasal sumatriptan for the acute treatment of migraine. International Intranasal Sumatriptan Study Group. ( Ashford, E; Dahlöf, C; Dawson, R; Gilhus, NE; Lüben, V; Noronha, D; Salonen, R; Warter, JM, 1994) |
| "Headache associated with the chronic use of medications has become a significant problem in the management of headache." | 2.43 | [Medication-overuse headache]. ( Katsarava, Z; Rabe, K, 2006) |
| "In the past ten years, migraine has really entered the field of science, with a number of major advances Despite theses advances, a lot has still to be done to understand what migraine really is and to improve the management of migraine sufferers." | 2.41 | [Migraine, ten years of progress]. ( Bousser, MG, 2000) |
| "Headache is one of the most common disorders that occurs during the early, developmental years of life." | 2.41 | Recent development in paediatric headache. ( Galli, F; Guidetti, V, 2001) |
| "This headache is distinguished by its response to indomethacin therapy." | 2.40 | [Chronic paroxysmal hemicrania]. ( Morales Asín, F, 1997) |
| "Although headache is among the most common pain complaints seen by physicians, the measurement of health-related quality of life (HRQoL) in headache patients is in its earliest stages." | 2.40 | Evolution of the measurement of quality of life in migraine. ( Solomon, GD, 1997) |
| "Headaches are a common entity in the ambulatory population." | 2.40 | Diagnosis, prophylaxis, and treatment of headaches in the athlete. ( Kaplan, B; Swain, RA, 1997) |
| "We believe that the use of these migraine models will provide even better treatment for migraine patients in the next millennium." | 2.40 | Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy. ( De Vries, P; Saxena, PR; Villalón, CM, 1999) |
| "The original migraine therapy, ergotamine, is highly effective in its rectal suppository formulation, when used at a subnauseating dosage." | 2.39 | Headache. ( Raskin, NH, 1994) |
| "That the 'primary' phenomenon in migraine with aura is neuronal ('spreading depression') seems increasingly probable, but the relationship of migraine with and without aura and of both to tension headache remains uncertain." | 2.38 | Headache and migraine. ( Ziegler, DK, 1992) |
| "Episodic cluster headache is more responsive to acute therapy than chronic." | 1.62 | Real-life treatment of cluster headache in a tertiary headache center - results from the Danish Cluster Headache Survey. ( Barloese, M; Jensen, RH; Lund, N; Petersen, AS, 2021) |
| "All patients were diagnosed as migraine by headache specialists and were treated with triptans, which resulted in satisfactory pain relief." | 1.51 | Orofacial Pain and Menstrually Related Migraine. ( Hatori, K; Hsu, YC; Imamura, Y; Nishihara, C; Noma, N; Ozasa, K; Young, A, 2019) |
| "The acute antimigraine efficacy of these remedies is very much dependent on the formulation used where, in general, parenteral formulations are more effective in relieving the symptoms of a migraine attack." | 1.38 | Headache currents commentary. ( Peatfield, R, 2012) |
| "The third woman had migraine but the attacks were not associated with HS." | 1.38 | Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine. ( Goadsby, PJ; Mathias, CJ; Viana, M, 2012) |
| "There was no difference in the treatments used or pain relief achieved between migraine, migrainous, and tension-type headaches." | 1.35 | Pain treatment and relief among patients with primary headache subtypes in the ED. ( Miner, J; Trainor, A, 2008) |
| "Sumatriptan was developed as an agent for the treatment of acute migraine." | 1.35 | Subcutaneous sumatriptan relieved migraine-like headache in two adolescents with aseptic meningitis. ( Alapati, D; Khanna, S; Pallimalli, SL; Prokhorov, S, 2008) |
| "All were treated for that headache with Synacthen and one also received sumatriptan before her seizures." | 1.31 | Unexplained fitting in three parturients suffering from postdural puncture headache. ( Oliver, CD; White, SA, 2002) |
| "Dihydroergotamine mesylate was also abortive in the few instances when the headache worsened." | 1.30 | Successful treatment of headache related to intravenous immunoglobulin with antimigraine medications. ( Finkel, AG; Howard, JF; Mann, JD, 1998) |
| "The pathophysiologies of migraine and cluster headache have a specific modifying property on cognitive processing reflected by a loss of cognitive habituation or an increased cognitive processing time." | 1.30 | Cognitive processing in primary headache: a study on event-related potentials. ( Bauer, B; Evers, S; Grotemeyer, KH; Husstedt, IW; Suhr, B, 1997) |
| "9% of the patients withdrew from the study because of insufficient efficacy or adverse events." | 1.30 | Open-labeled long-term study of the efficacy, safety, and tolerability of subcutaneous sumatriptan in acute migraine treatment. ( Göbel, H; Heinze, A; Heinze-Kuhn, K; Lindner, V; Stolze, H, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 61 (40.94) | 18.2507 |
| 2000's | 53 (35.57) | 29.6817 |
| 2010's | 22 (14.77) | 24.3611 |
| 2020's | 13 (8.72) | 2.80 |
| Authors | Studies |
|---|---|
| Medrea, I | 1 |
| Christie, S | 1 |
| Tepper, SJ | 2 |
| Thavorn, K | 1 |
| Hutton, B | 1 |
| Panda, PK | 1 |
| Ramachandran, A | 1 |
| Sharawat, IK | 1 |
| Bhat, NK | 1 |
| Peng, KP | 1 |
| Jürgens, T | 1 |
| Basedau, H | 1 |
| Ortlieb, L | 1 |
| May, A | 2 |
| Chhabra, N | 1 |
| Grill, MF | 1 |
| Singh, RBH | 1 |
| Hauser Chatterjee, J | 1 |
| Hartford, EA | 1 |
| Law, E | 1 |
| Barry, D | 1 |
| Blume, H | 1 |
| Chanchlani, R | 1 |
| Agrawal, A | 1 |
| Janjua, D | 1 |
| Hafsa, SN | 1 |
| Abdelmonem, H | 1 |
| Abdelhay, HM | 1 |
| Abdelwadoud, GT | 1 |
| Alhosini, ANM | 1 |
| Ahmed, AE | 1 |
| Mohamed, SW | 1 |
| Al-Dardery, NM | 1 |
| Abd-ElGawad, M | 1 |
| Kamel, MA | 1 |
| Tajti, J | 1 |
| Csáti, A | 1 |
| Szok, D | 1 |
| Oskoui, M | 1 |
| Pringsheim, T | 2 |
| Holler-Managan, Y | 1 |
| Potrebic, S | 1 |
| Billinghurst, L | 1 |
| Gloss, D | 1 |
| Hershey, AD | 1 |
| Licking, N | 1 |
| Sowell, M | 1 |
| Victorio, MC | 1 |
| Gersz, EM | 1 |
| Leininger, E | 1 |
| Zanitsch, H | 1 |
| Yonker, M | 1 |
| Mack, K | 1 |
| Al-Karagholi, MA | 2 |
| Ghanizada, H | 3 |
| Hansen, JM | 1 |
| Skovgaard, LT | 1 |
| Olesen, J | 7 |
| Larsson, HBW | 3 |
| Amin, FM | 4 |
| Ashina, M | 5 |
| Nishihara, C | 1 |
| Hatori, K | 1 |
| Hsu, YC | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.[NCT03609008] | 20 participants (Actual) | Interventional | 2018-06-26 | Completed | |||
| The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects[NCT03585894] | 34 participants (Actual) | Interventional | 2018-08-01 | Completed | |||
| Pretreatment With Sumatriptan on Cilostazol Induced Headache in Healthy Volunteers. Development of a Pragmatic Migraine Model[NCT03156920] | 30 participants (Actual) | Interventional | 2017-05-23 | Completed | |||
| Effect of Sumatriptan on the Postoperative Quality of Recovery After Elective Minimally Invasive Craniotomy[NCT01632657] | 40 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| Understanding the Role of the External Carotid Artery in the Pathophysiology of Migraine Pain[NCT03026101] | 20 participants (Anticipated) | Interventional | 2017-01-31 | Enrolling by invitation | |||
| A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Headache[NCT02440997] | 46 participants (Actual) | Interventional | 2015-03-25 | Completed | |||
| The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031] | Phase 4 | 54 participants (Actual) | Interventional | 2016-03-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 33.7 |
| Study Arm | 21.2 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 63.5 |
| Study Arm | 43.5 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 38.9 |
| Study Arm | 22.9 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 2 |
| Study Arm | 3 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 3 |
| Study Arm | 3 |
38 reviews available for sumatriptan and Headache
| Article | Year |
|---|---|
Network meta-analysis of therapies for cluster headache: Effects of acute therapies for episodic and chronic cluster.
Topics: Adolescent; Adult; Bayes Theorem; Cluster Headache; Headache; Humans; Nasal Sprays; Network Meta-Ana | 2022 |
Post-COVID Headache: A Literature Review.
Topics: COVID-19; Epilepsy; Female; Headache; Humans; Migraine Disorders; Sumatriptan | 2022 |
Sumatriptan as a First-Line Treatment for Headache in the Pediatric Emergency Department.
Topics: Child; Emergency Service, Hospital; Female; Headache; Humans; Male; Migraine Disorders; Retrospectiv | 2023 |
The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review.
Topics: Adolescent; Child; Headache; Humans; Migraine Disorders; Naproxen; Sumatriptan; Tryptamines | 2023 |
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea | 2023 |
[Sumatriptan-naproxen sodium fix-dose combination for acute migraine treatment, a review].
Topics: Double-Blind Method; Drug Therapy, Combination; Headache; Humans; Migraine Disorders; Naproxen; Qual | 2023 |
Practice guideline update summary: Acute treatment of migraine in children and adolescents: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society.
Topics: Academies and Institutes; Adolescent; Child; Drug Combinations; Headache; Humans; Migraine Disorders | 2019 |
Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Headache; Humans | 2014 |
Headache research in 2015: progress in migraine treatment.
Topics: Analgesics; Antibodies, Monoclonal; Biomedical Research; Headache; Humans; Migraine Disorders; Sumat | 2016 |
Are there pharmacologic agents that safely and effectively treat post-lumbar puncture headache?
Topics: Adrenocorticotropic Hormone; Caffeine; Central Nervous System Stimulants; Headache; Humans; Injectio | 2013 |
The management of cyclic vomiting syndrome: a systematic review.
Topics: Adrenergic beta-Antagonists; Age of Onset; Antidepressive Agents, Tricyclic; Depression; Female; Hea | 2012 |
Effects of glyceryl trinitrate and calcitonin gene-related peptide on BOLD signal and arterial diameter: methodological studies by fMRI and MRA.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Brain; Calcitonin Gene-Related Peptide; Cerebral | 2012 |
Medication overuse headache.
Topics: Analgesics; Ergot Alkaloids; Headache; Humans; Migraine Disorders; Narcotics; Serotonin Receptor Ago | 2001 |
Sumatriptan: pharmacological basis and clinical results.
Topics: Administration, Inhalation; Headache; Humans; Injections; Migraine Disorders; Patient Satisfaction; | 2001 |
Acute treatment of pediatric headache in the emergency department and inpatient settings.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Dihydroergotamine; D | 2005 |
[Treatment of cluster headache].
Topics: Cluster Headache; Facial Pain; Headache; Humans; Oxygen Inhalation Therapy; Sumatriptan; Trigeminal | 2005 |
[Medication-overuse headache].
Topics: Acute Disease; Analgesics; Analgesics, Non-Narcotic; Chronic Disease; Ergotamine; Female; Headache; | 2006 |
[Acute and chronic headaches].
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
Favorable response to analgesics does not predict a benign etiology of headache.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Headache; Humans; Serotonin Recept | 2008 |
Headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ergotamine; Headache; Humans; Migraine Disorders; Sumatript | 1994 |
[Diagnosis and therapy of headaches].
Topics: Adrenergic beta-Antagonists; Ergotamine; Headache; Humans; Indoles; Serotonin Receptor Agonists; Sul | 1993 |
Evolution of the measurement of quality of life in migraine.
Topics: Attitude to Health; Emotions; Headache; Health Status; Humans; Mental Health; Migraine Disorders; Pa | 1997 |
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; | 1997 |
[Chronic paroxysmal hemicrania].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diagnosis, Differential; Female; He | 1997 |
Update on headache.
Topics: Analgesics, Non-Narcotic; Ergotamine; Headache; Humans; Patient Selection; Sumatriptan; Vasoconstric | 1998 |
Medical management of posttraumatic headaches: pharmacological and physical treatment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Craniocerebral Trauma; Ergotamine; Headach | 1999 |
Medication-induced headache: overview and systematic review of therapeutic approaches.
Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Chronic Disease; Ergolines; Headache; Humans; M | 1999 |
Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy.
Topics: Animals; Disease Models, Animal; Forecasting; Headache; Humans; Migraine Disorders; Models, Biologic | 1999 |
[Migraine, ten years of progress].
Topics: Brain; Headache; Humans; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan | 2000 |
Recent development in paediatric headache.
Topics: Adolescent; Analgesics; Child; Clinical Trials as Topic; Diagnosis, Differential; Headache; Humans; | 2001 |
Triptans are all different.
Topics: Carbazoles; Headache; Humans; Indoles; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Su | 2001 |
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psyc | 2002 |
Triptans: do they differ?
Topics: Clinical Trials as Topic; Dosage Forms; Headache; Humans; Serotonin Receptor Agonists; Sumatriptan | 2002 |
Triptans: are they all the same?
Topics: Drug Interactions; Headache; Humans; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan | 2002 |
Cryptic pituitary hemorrhage presenting with headache.
Topics: Adenoma; Cysts; Headache; Hemorrhage; Humans; Male; Middle Aged; Pituitary Neoplasms; Sumatriptan | 2002 |
[The latest in headache treatment].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Angiotensin-Converting | 2002 |
Headache and migraine.
Topics: Arousal; Brain; Electroencephalography; Headache; Humans; Indoles; Migraine Disorders; Regional Bloo | 1992 |
Management of headache.
Topics: Diagnosis, Differential; Headache; Humans; Indoles; Migraine Disorders; Sulfonamides; Sumatriptan; V | 1992 |
27 trials available for sumatriptan and Headache
| Article | Year |
|---|---|
Sumatriptan prevents central sensitization specifically in the trigeminal dermatome in humans.
Topics: Capsaicin; Central Nervous System Sensitization; Headache; Humans; Hyperalgesia; Migraine Disorders; | 2022 |
Levcromakalim, an Adenosine Triphosphate-Sensitive Potassium Channel Opener, Dilates Extracerebral but not Cerebral Arteries.
Topics: Adult; Cromakalim; Double-Blind Method; Female; Headache; Humans; Ion Channel Gating; Male; Meningea | 2019 |
Investigation of sumatriptan and ketorolac trometamol in the human experimental model of headache.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Female; Hea | 2020 |
Pre-treatment with sumatriptan for cilostazol induced headache in healthy volunteers.
Topics: Adult; Cilostazol; Cross-Over Studies; Double-Blind Method; Female; Headache; Healthy Volunteers; Hu | 2018 |
Meningeal contribution to migraine pain: a magnetic resonance angiography study.
Topics: Adolescent; Adult; Carotid Arteries; Cilostazol; Female; Headache; Humans; Magnetic Resonance Angiog | 2019 |
Sumatriptan improves postoperative quality of recovery and reduces postcraniotomy headache after cranial nerve decompression.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cranial Nerve Diseases; Cranial Nerves; Double-Blind Met | 2016 |
Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers.
Topics: Adult; Calcitonin Gene-Related Peptide; Cross-Over Studies; Female; Headache; Humans; Male; Neuropep | 2010 |
Treating headache recurrence after emergency department discharge: a randomized controlled trial of naproxen versus sumatriptan.
Topics: Adult; Analgesics; Double-Blind Method; Emergency Service, Hospital; Female; Headache; Humans; Male; | 2010 |
Dilation by CGRP of middle meningeal artery and reversal by sumatriptan in normal volunteers.
Topics: Adult; Area Under Curve; Blood Pressure; Calcitonin Gene-Related Peptide; Confidence Intervals; Doub | 2010 |
Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers.
Topics: Adult; Blood Pressure; Carbon Dioxide; Female; Headache; Heart Rate; Humans; Magnetic Resonance Angi | 2012 |
A randomized controlled trial of a comprehensive migraine intervention prior to discharge from an emergency department.
Topics: Adult; Emergency Service, Hospital; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; | 2012 |
Transient minor improvement of high altitude headache by sumatriptan.
Topics: Adult; Altitude Sickness; Chi-Square Distribution; Double-Blind Method; Female; Headache; Humans; Ma | 2002 |
Subcutaneous sumatriptan provides symptomatic relief at any pain intensity or time during the migraine attack.
Topics: Adult; Cross-Over Studies; Female; Headache; Humans; Injections, Subcutaneous; Male; Middle Aged; Mi | 2006 |
Does earlier headache response equate to earlier return to functioning in patients suffering from migraine?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Comorbidity; Double-Blind Method; Female; Headache; Huma | 2006 |
Sumatriptan for prevention of acute mountain sickness: randomized clinical trial.
Topics: Acute Disease; Adolescent; Adult; Altitude Sickness; Double-Blind Method; Drug Eruptions; Endpoint D | 2007 |
Ibuprofen versus sumatriptan for high-altitude headache.
Topics: Administration, Oral; Adult; Altitude Sickness; Cross-Over Studies; Double-Blind Method; Female; Hea | 1995 |
Intranasal sumatriptan for the acute treatment of migraine. International Intranasal Sumatriptan Study Group.
Topics: Acute Disease; Administration, Intranasal; Adult; Double-Blind Method; Drug Tolerance; Female; Heada | 1994 |
Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Cerebrovascular Circulation; Double-Blind Method; | 1996 |
Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs.
Topics: Adult; Blood Flow Velocity; Brain; Cross-Over Studies; Double-Blind Method; Female; Headache; Humans | 1996 |
The pharmacodynamics of sumatriptan in nitroglycerin-induced headache.
Topics: Adult; Analysis of Variance; Area Under Curve; Brain; Cerebral Arteries; Electrocardiography; Headac | 1999 |
Sumatriptan in patients with postdural puncture headache.
Topics: Adult; Anesthesia, Epidural; Blood Patch, Epidural; Female; Headache; Humans; Injections, Subcutaneo | 2000 |
Clinical features of withdrawal headache following overuse of triptans and other headache drugs.
Topics: Adult; Analgesics; Drug Therapy, Combination; Ergotamine; Female; Headache; Humans; Indoles; Male; M | 2001 |
Intranasal sumatriptan in post-ECT headache: results of an open-label trial.
Topics: Administration, Intranasal; Adolescent; Adult; Electroconvulsive Therapy; Female; Headache; Humans; | 2001 |
Tolerability and safety of frovatriptan with short- and long-term use for treatment of migraine and in comparison with sumatriptan.
Topics: Acute Disease; Adult; Carbazoles; Clinical Trials as Topic; Dizziness; Dose-Response Relationship, D | 2002 |
CNS effects of sumatriptan and rizatriptan in healthy female volunteers.
Topics: Adult; Affect; Brain; Cognition; Cross-Over Studies; Dizziness; Double-Blind Method; Electroencephal | 2002 |
The 5-HT1-like agonist sumatriptan has a significant effect in chronic tension-type headache.
Topics: Adult; Aged; Chronic Disease; Double-Blind Method; Female; Headache; Hemodynamics; Humans; Indoles; | 1992 |
Subcutaneous sumatriptan in the treatment of headache during withdrawal from drug-induced headache.
Topics: Adult; Cerebral Arteries; Cerebrovascular Circulation; Double-Blind Method; Ergotamine; Female; Head | 1991 |
84 other studies available for sumatriptan and Headache
| Article | Year |
|---|---|
Feasibility, Utility, and Interrater Reliability of the Cluster Headache Severity Scale, Cluster Headache Quality of Life, Cluster Headache Index, and 6-Item Headache Impact Test in Pediatric Cluster Headache.
Topics: Child; Cluster Headache; Feasibility Studies; Female; Headache; Humans; Male; Nasal Sprays; Predniso | 2022 |
Orofacial Pain and Menstrually Related Migraine.
Topics: Adult; Facial Pain; Female; Headache; Humans; Middle Aged; Migraine Disorders; Sumatriptan | 2019 |
Capsaicin-sensitive fibers mediate periorbital allodynia and activation of inflammatory cells after traumatic brain injury in rats: Involvement of TRPV1 channels in post-traumatic headache.
Topics: Animals; Animals, Newborn; Capsaicin; Headache; Inflammation Mediators; Male; Nerve Fibers; Post-Tra | 2020 |
Pearls & Oy-sters: A Journey Through Reversible Cerebral Vasoconstriction Syndrome: Sex, Drugs, and Headaches.
Topics: Adult; Angiography, Digital Subtraction; Cerebral Hemorrhage; Cerebrovascular Disorders; Coitus; Con | 2021 |
Real-life treatment of cluster headache in a tertiary headache center - results from the Danish Cluster Headache Survey.
Topics: Cluster Headache; Cross-Sectional Studies; Denmark; Headache; Humans; Oxygen; Sumatriptan; Surveys a | 2021 |
[In process].
Topics: Adolescent; Adrenergic beta-Antagonists; Age Factors; Analgesics; Behavior Therapy; Child; Flunarizi | 2016 |
Recurrent Headache Increases Blood-Brain Barrier Permeability and VEGF Expression in Rats.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Headache; Hyperalgesia; Inflammation; Male; Mi | 2018 |
Availability of Effective Evidence-Based Symptomatic Treatments for Cluster Headache in the EU Countries-A Survey of the European Headache Alliance and European Headache Federation.
Topics: Cluster Headache; European Union; Headache; Humans; Sumatriptan; Surveys and Questionnaires | 2020 |
Teaching case: hypertensiveheadache.
Topics: Brain Diseases; Cerebral Hemorrhage; Female; Headache; Humans; Hypertension; Middle Aged; Seizures; | 2013 |
Subcutaneous sumatriptan relieved migraine-like headache in two adolescents with aseptic meningitis.
Topics: Adolescent; Female; Headache; Humans; Injections, Subcutaneous; Male; Meningitis, Aseptic; Serotonin | 2008 |
Pain treatment and relief among patients with primary headache subtypes in the ED.
Topics: Adolescent; Adult; Aged; Droperidol; Emergency Service, Hospital; Headache; Humans; Middle Aged; Pai | 2008 |
Intravenous aspirin (lysine acetylsalicylate) in the inpatient management of headache.
Topics: Aspirin; Disease Management; Headache; Humans; Infusions, Intravenous; Randomized Controlled Trials | 2011 |
Cluster headache or giant cell arteritis?
Topics: Aged; Anti-Inflammatory Agents; Cluster Headache; Diagnosis, Differential; Female; Giant Cell Arteri | 2008 |
Headache currents commentary.
Topics: Analgesics; Animals; Dihydroergotamine; Ergotamine; Headache; Humans; Methysergide; Migraine Disorde | 2012 |
Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Diagnosis, Differential; Dihydroergotamine; Ergotami | 2012 |
Unexplained fitting in three parturients suffering from postdural puncture headache.
Topics: Adult; Analgesia, Epidural; Anesthesia, Obstetrical; Cosyntropin; Female; Headache; Humans; Seizures | 2002 |
Ergot and triptan overuse in Austria--an evaluation of clinical data and cost.
Topics: Adult; Aged; Austria; Ergot Alkaloids; Female; Headache; Humans; Male; Middle Aged; Oxazolidinones; | 2002 |
Misdiagnosis of migraine.
Topics: Adult; Diagnostic Errors; Headache; Humans; Male; Migraine Disorders; Practice Guidelines as Topic; | 2003 |
Response to sumatriptan in headache of MELAS syndrome.
Topics: Adult; Drug Evaluation; Female; Headache; Humans; Hyperemia; MELAS Syndrome; Parietal Lobe; Phenotyp | 2003 |
[Headache in children].
Topics: Adrenergic beta-Antagonists; Analgesics, Non-Narcotic; Antiemetics; Child; Headache; Humans; Propran | 2003 |
[Improved pharmacokinetics. Fast tryptan with sustained response].
Topics: Administration, Oral; Controlled Clinical Trials as Topic; Delayed-Action Preparations; Female; Head | 2003 |
CNS effects of sumatriptan and rizatriptan.
Topics: Adult; Affect; Brain; Cognition; Cross-Over Studies; Dizziness; Double-Blind Method; Electroencephal | 2004 |
Headaches that could spell trouble.
Topics: Dihydroergotamine; Headache; Humans; Migraine Disorders; Sumatriptan | 2004 |
Elevated levels of circulating trace amines in primary headaches.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cluster Headache; Diet; Female; Headache; H | 2004 |
Treatment of primary headache in the emergency department.
Topics: Anesthetics, Local; Bupivacaine; Emergency Service, Hospital; Headache; Humans; Injections, Intramus | 2004 |
Daily sumatriptan for detoxification from rebound.
Topics: Administration, Oral; Headache; Humans; Inactivation, Metabolic; Migraine Disorders; Sumatriptan | 1998 |
The headache of SAH responds to sumatriptan.
Topics: Fatal Outcome; Female; Headache; Humans; Middle Aged; Serotonin Antagonists; Subarachnoid Hemorrhage | 2005 |
The perils of misinterpreting a treatment response.
Topics: Diagnostic Errors; Fatal Outcome; Female; Headache; Humans; Middle Aged; Serotonin Receptor Agonists | 2005 |
Open label study of intranasal sumatriptan (Imigran) for footballer's headache.
Topics: Administration, Intranasal; Headache; Humans; Migraine Disorders; Migraine without Aura; Pain Measur | 2005 |
Prediction of headache response in migraine treatment.
Topics: Comorbidity; Computer Simulation; Decision Support Systems, Clinical; Dose-Response Relationship, Dr | 2006 |
Intranasal sumatriptan for prevention of post-ECT headaches.
Topics: Administration, Intranasal; Electroconvulsive Therapy; Headache; Humans; Serotonin Receptor Agonists | 2006 |
Intracranial hypotension following chiropractic spinal manipulation.
Topics: Adult; Headache; Humans; Male; Serotonin Receptor Agonists; Sumatriptan | 2006 |
Sumatriptan for the treatment of undifferentiated primary headaches in the ED.
Topics: Adult; Emergency Service, Hospital; Female; Headache; Humans; Male; Migraine Disorders; Minnesota; P | 2007 |
Recurrent headache due to MS plaque.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents; Female; Headache; Humans; Immunoglobulins, Intravenous | 2008 |
Migraine-like headache in intracranial haemorrhage is alleviated by sumatriptan and almotriptan.
Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Headache; Humans; Intracranial Hemorrhage | 2008 |
[Headache after spinal anesthesia treated with sumatriptan].
Topics: Adult; Analgesics; Anesthesia, Spinal; Headache; Humans; Male; Sumatriptan | 1995 |
Another complication of the combined extradural-subarachnoid technique.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; | 1995 |
Health-related quality of life in headache research.
Topics: Headache; Health Status; Humans; Longitudinal Studies; Quality of Life; Sumatriptan | 1995 |
SUNCT syndrome.
Topics: Adult; Aged; Conjunctival Diseases; Ergotamine; Female; Headache; Humans; Male; Sumatriptan; Syndrom | 1995 |
Sumatriptan and daily headache.
Topics: Headache; Humans; Sumatriptan; Time Factors | 1995 |
[Headache caused by analgesics].
Topics: Acetaminophen; Adult; Female; Headache; Humans; Middle Aged; Migraine Disorders; Sumatriptan | 1994 |
Ergotamine-induced headache can be sustained by sumatriptan daily intake.
Topics: Adult; Ergotamine; Female; Headache; Humans; Sumatriptan | 1994 |
Sumatriptan for high-altitude headache.
Topics: Adult; Altitude Sickness; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Sumatript | 1994 |
Effects of the serotonin-receptor agonist sumatriptan on postdural puncture headache: report of six cases.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Female; Headache; Humans; Male; Pregnancy; Spinal P | 1994 |
Sumatriptan and giant cell arteritis.
Topics: Aged; Female; Giant Cell Arteritis; Headache; Humans; Sumatriptan | 1994 |
Transient resolution of headache in giant cell temporal arteritis after sumatriptan.
Topics: Aged; Female; Giant Cell Arteritis; Headache; Humans; Sumatriptan; Time Factors | 1993 |
Subcutaneous sumatriptan in the treatment of acute episodes of posttraumatic headache.
Topics: Adult; Female; Headache; Humans; Indoles; Injections, Subcutaneous; Male; Serotonin Receptor Agonist | 1993 |
Coexistence of migraine and idiopathic intracranial hypertension without papilledema.
Topics: Acetazolamide; Adolescent; Adult; Dihydroergotamine; Diuretics; Ergotamine; Female; Follow-Up Studie | 1996 |
Easy therapeutical management of sumatriptan-induced daily headache.
Topics: Adult; Aged; Female; Headache; Humans; Middle Aged; Sumatriptan; Time Factors | 1996 |
[Limits of sumatriptan in the treatment of headache after dura mater puncture].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Patch, Epidural; Dura Mater; Female; Hea | 1996 |
Amitriptyline and dexamethasone combined treatment in drug-induced headache.
Topics: Adult; Amitriptyline; Analgesics; Dexamethasone; Drug Therapy, Combination; Female; Headache; Humans | 1996 |
Participation of 5-HT1-like and 5-HT2A receptors in the contraction of human temporal artery by 5-hydroxytryptamine and related drugs.
Topics: Adult; Aged; Benzazepines; Collagenases; Endothelium, Vascular; Female; Headache; Humans; In Vitro T | 1996 |
Headache recurrence.
Topics: Headache; Humans; Recurrence; Sumatriptan | 1996 |
Risk factors for headache recurrence after sumatriptan: a study in 366 migraine patients.
Topics: Adult; Female; Headache; Humans; Male; Middle Aged; Prognosis; Recurrence; Risk Factors; Sumatriptan | 1996 |
Nitroglycerin-induced headache.
Topics: Arteriovenous Anastomosis; Dose-Response Relationship, Drug; Head; Headache; Humans; Migraine Disord | 1996 |
Prescribing practices for the management of headache in Newfoundland and Labrador.
Topics: Analgesics; Cohort Studies; Drug Prescriptions; Headache; Humans; Migraine Disorders; Newfoundland a | 1996 |
Sumatriptan: an alternative to epidural blood patch?
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Patch, Epidural; Female; Headache; Humans; Sero | 1996 |
Cognitive processing in primary headache: a study on event-related potentials.
Topics: Adolescent; Adult; Aged; Cluster Headache; Cognition; Evoked Potentials; Female; Habituation, Psycho | 1997 |
The use of sumatriptan in the treatment of postdural puncture headache.
Topics: Adult; Anesthesia, Spinal; Dura Mater; Female; Headache; Humans; Serotonin Receptor Agonists; Sumatr | 1997 |
Sumatriptan and postdural puncture headache.
Topics: Blood Patch, Epidural; Dura Mater; Headache; Humans; Sumatriptan; Vasoconstrictor Agents | 1997 |
[Failure of sumatriptan in post-dural puncture headache].
Topics: Adult; Anesthesia, Epidural; Female; Headache; Humans; Serotonin Receptor Agonists; Sumatriptan | 1997 |
Chronic paroxysmal hemicrania and hemicrania continua: lack of efficacy of sumatriptan.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dosage Forms; Female; Headach | 1998 |
Inappropriate use of sumatriptan: population based register and interview study.
Topics: Adult; Chronic Disease; Denmark; Female; Headache; Health Services Misuse; Humans; Male; Middle Aged | 1998 |
Successful treatment of headache related to intravenous immunoglobulin with antimigraine medications.
Topics: Adult; Analgesics, Non-Narcotic; Dihydroergotamine; Female; Headache; Humans; Immunoglobulins, Intra | 1998 |
Sumatriptan was effective in electroconvulsive therapy (ECT) headache.
Topics: Electroconvulsive Therapy; Headache; Humans; Serotonin Receptor Agonists; Sumatriptan | 1998 |
Sumatriptan for post-ECT headache.
Topics: Administration, Oral; Adult; Depressive Disorder; Electroconvulsive Therapy; Female; Headache; Human | 1998 |
A triptan too far?
Topics: Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
A triptan too far?
Topics: Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
The use of sumatriptan in the treatment of postdural puncture headache after accidental lumbar puncture complicated a blood patch procedure.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Blood Patch, Epidural; Female; Headache; Humans; | 1999 |
Drug-induced headaches.
Topics: Analgesics, Non-Narcotic; Ergotamine; Headache; Humans; Indoles; Oxazoles; Oxazolidinones; Piperidin | 1999 |
Open-labeled long-term study of the efficacy, safety, and tolerability of subcutaneous sumatriptan in acute migraine treatment.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Analgesics; Antiemetics; Calcium Channel Block | 1999 |
Headache in Meniere's disease.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Tricyclic; Carbamazepin | 1999 |
Alteration in nature of cluster headache during subcutaneous administration of sumatriptan.
Topics: Adult; Chronic Disease; Cluster Headache; Headache; Humans; Injections, Subcutaneous; Male; Middle A | 2000 |
Headache relief after sumatriptan in a patient with pituitary macroadenoma.
Topics: Adenoma, Chromophobe; Adult; Female; Headache; Humans; Pituitary Neoplasms; Sumatriptan | 2000 |
[Hemicranial headache caused by orbital cellulitis successfully treated with sumatriptan].
Topics: Adult; Cellulitis; Headache; Humans; Male; Orbital Diseases; Remission Induction; Serotonin Receptor | 2000 |
Vestibular schwannoma surgery and headache.
Topics: Adult; Aged; Anesthetics, Local; Dizziness; Female; Follow-Up Studies; Headache; Humans; Lidocaine; | 2000 |
Management of a septic patient with postdural puncture headache.
Topics: Adult; Blood Patch, Epidural; Contraindications; Dura Mater; Female; Headache; Humans; Sepsis; Serot | 2000 |
A comment on time-to-event analysis for headache relief.
Topics: Analgesics; Headache; Humans; Indoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as | 2000 |
Sumatriptan for headache caused by head and neck cancer.
Topics: Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Fatal Outcome; Head and Neck Neoplasms; Headache; | 2000 |
Dramatic headache relief after sumatriptan in a patient with a pituitary macroadenoma.
Topics: Adenoma; Adult; Female; Headache; Humans; Injections, Subcutaneous; Pituitary Neoplasms; Sumatriptan | 1999 |
Headache due to antimigraine 5HT1 receptor agonists.
Topics: Analgesics; Headache; Headache Disorders; Humans; Indoles; Oxazolidinones; Piperidines; Prospective | 1999 |
Criteria for use of sumatriptan in adult inpatients and outpatients.
Topics: Adult; Ambulatory Care; Headache; Humans; Indoles; Inpatients; Sulfonamides; Sumatriptan; Vasoconstr | 1992 |
Headache recurrence after subcutaneous sumatriptan and early treatment.
Topics: Adult; Female; Headache; Humans; Indoles; Injections, Subcutaneous; Male; Middle Aged; Recurrence; S | 1992 |
Serotonin receptors and headache.
Topics: Cluster Headache; Headache; Humans; Indoles; Migraine Disorders; Receptors, Serotonin; Sulfonamides; | 1991 |