Page last updated: 2024-11-04

sumatriptan and Flushing

sumatriptan has been researched along with Flushing in 3 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Flushing: A transient reddening of the face that may be due to fever, certain drugs, exertion, or stress.

Research Excerpts

ExcerptRelevanceReference
"We established a clinical experimental model of rosacea features and showed that sumatriptan was able to attenuate PACAP38-induced rosacea flushing and edema."9.41Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan. ( Ashina, M; Christensen, CE; Coskun, H; Egeberg, A; Ghanizada, H; Thyssen, JP; Wienholtz, NKF; Zhang, DG, 2021)
"We established a clinical experimental model of rosacea features and showed that sumatriptan was able to attenuate PACAP38-induced rosacea flushing and edema."5.41Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan. ( Ashina, M; Christensen, CE; Coskun, H; Egeberg, A; Ghanizada, H; Thyssen, JP; Wienholtz, NKF; Zhang, DG, 2021)
"When compared at 2 and 24 hours, aggressive (20 mg dosed up to four times) IV metoclopramide and 6 mg of subcutaneous sumatriptan relieved migraine headache pain comparably."2.71A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines. ( Bijur, PE; Corbo, J; Esses, D; Friedman, BW; Gallagher, EJ; Lipton, RB; Solorzano, C, 2005)
"The third woman had migraine but the attacks were not associated with HS."1.38Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine. ( Goadsby, PJ; Mathias, CJ; Viana, M, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Wienholtz, NKF1
Christensen, CE1
Coskun, H1
Zhang, DG1
Ghanizada, H1
Egeberg, A1
Thyssen, JP1
Ashina, M1
Viana, M1
Mathias, CJ1
Goadsby, PJ1
Friedman, BW1
Corbo, J1
Lipton, RB1
Bijur, PE1
Esses, D1
Solorzano, C1
Gallagher, EJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigation of PACAP38-induced Headache and Rosacea-like Symptoms in Patients With Rosacea[NCT03878784]38 participants (Actual)Interventional2018-11-12Completed
Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen[NCT01522326]300 participants (Anticipated)Interventional2012-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for sumatriptan and Flushing

ArticleYear
Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:7

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Edema; Face; Female; Flushing; Humans; Infusions, In

2021
A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.
    Neurology, 2005, Feb-08, Volume: 64, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dizziness;

2005

Other Studies

1 other study available for sumatriptan and Flushing

ArticleYear
Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine.
    Journal of neurology, neurosurgery, and psychiatry, 2012, Volume: 83, Issue:6

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Diagnosis, Differential; Dihydroergotamine; Ergotami

2012