sumatriptan has been researched along with Esophageal Reflux in 2 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sumatriptan prevents the natural decay in rate of transient LES relaxations that occurs after a meal and favors the occurrence of gastroesophageal reflux despite increasing LES pressure." | 9.09 | Effect of sumatriptan, a 5HT1 agonist, on the frequency of transient lower esophageal sphincter relaxations and gastroesophageal reflux in healthy subjects. ( Coulie, B; Holloway, RH; Janssens, J; Missotten, T; Sifrim, D; Tack, J; Zelter, A, 1999) |
| "Sumatriptan prevents the natural decay in rate of transient LES relaxations that occurs after a meal and favors the occurrence of gastroesophageal reflux despite increasing LES pressure." | 5.09 | Effect of sumatriptan, a 5HT1 agonist, on the frequency of transient lower esophageal sphincter relaxations and gastroesophageal reflux in healthy subjects. ( Coulie, B; Holloway, RH; Janssens, J; Missotten, T; Sifrim, D; Tack, J; Zelter, A, 1999) |
| "Experimental gastroduodenal ulcer was simulated after pre-injection of serotonin; gastroesophageal reflux disease and duodenogastral reflux were induced." | 1.35 | Role of serotoninergic system in the development of gastrointestinal diseases. ( Lychkova, AE, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lychkova, AE | 1 |
| Sifrim, D | 1 |
| Holloway, RH | 1 |
| Tack, J | 1 |
| Zelter, A | 1 |
| Missotten, T | 1 |
| Coulie, B | 1 |
| Janssens, J | 1 |
1 trial available for sumatriptan and Esophageal Reflux
| Article | Year |
|---|---|
Effect of sumatriptan, a 5HT1 agonist, on the frequency of transient lower esophageal sphincter relaxations and gastroesophageal reflux in healthy subjects.
Topics: Adolescent; Adult; Eating; Esophagogastric Junction; Female; Gastric Emptying; Gastric Fundus; Gastr | 1999 |
1 other study available for sumatriptan and Esophageal Reflux
| Article | Year |
|---|---|
Role of serotoninergic system in the development of gastrointestinal diseases.
Topics: Acetic Acid; Animals; Duodenogastric Reflux; Esophagus; Female; Gastroesophageal Reflux; Gastrointes | 2009 |