sumatriptan has been researched along with Emesis in 34 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present studies, therefore, we used Suncus murinus, a species of insectivore capable of emesis, to investigate if the vanilloid receptor agonist resiniferatoxin is capable of modeling the emesis associated with migraine." | 7.73 | Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). ( Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C, 2005) |
| "To describe a patient with cyclic vomiting who was treated successfully with sumatriptan, a serotonin, agonist." | 7.69 | Sumatriptan in the treatment of cyclic vomiting. ( Benson, JM; Book, LS; Zorn, SL, 1995) |
| "Sumatriptan was administered either subcutaneously [(age x 4 + 20)/100 x 3 mg] or by nasal spray (NS; 20 mg)." | 6.76 | Sumatriptan as a treatment for cyclic vomiting syndrome: a clinical trial. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kikuchi, A; Kodama, H; Mochizuki, D; Nakamoto, N; Ogita, K, 2011) |
| "Cyclic vomiting syndrome is an increasingly recognized cause of nausea and vomiting in adults." | 5.36 | Adult cyclic vomiting syndrome successfully treated with intranasal sumatriptan. ( Kowalczyk, M; Parkman, H; Ward, L, 2010) |
| "The authors present a 14-year-old girl with 18q- syndrome combined with cyclic vomiting syndrome." | 5.35 | Successful treatment with sumatriptan in a case with cyclic vomiting syndrome combined with 18q- syndrome. ( Haginoya, K; Hirose, M; Kakisaka, Y; Munakata, M; Sato, I; Sato, T; Tsuchiya, S; Uematsu, M; Wakusawa, K, 2009) |
| " Addition of metoclopramide 10 mg improves relief of nausea and vomiting." | 4.89 | Aspirin with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Kirthi, V; Moore, RA, 2013) |
| " Addition of metoclopramide 10 mg improves relief of nausea and vomiting." | 4.86 | Aspirin with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Kirthi, V; McQuay, HJ; Moore, RA, 2010) |
| "Sumatriptan is a 5-HT1B/D receptor agonist of documented efficacy in relieving migraine and associated symptoms such as nausea and vomiting." | 4.81 | Gastric motor effects of triptans: open questions and future perspectives. ( Cipolla, G; Crema, F; De Ponti, F; Frigo, G; Moro, E; Sacco, S, 2001) |
| "This pooled analysis (N=1773) used data from three randomized, placebo-controlled, phase III trials (studies A, B, and C) to determine the incidence of migraine-associated symptoms (defined as nausea, vomiting, photophobia, and phonophobia) 2 hours after a single oral dose of study medication (almotriptan, sumatriptan, or placebo)." | 4.81 | Almotriptan reduces the incidence of migraine-associated symptoms: a pooled analysis. ( Cady, R, 2002) |
| "Sumatriptan succinate and prochlorperazine maleate are a clinically proven combination for treating migraine and associated nausea and vomiting." | 4.12 | Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization. ( Anwer, UU; Bukhari, NI; Hafiz, MA; Hussain, A; Javed, S; Rasool, F; Raza, SA; Shah, PA; Shamim, R, 2022) |
| " In the present studies, therefore, we used Suncus murinus, a species of insectivore capable of emesis, to investigate if the vanilloid receptor agonist resiniferatoxin is capable of modeling the emesis associated with migraine." | 3.73 | Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). ( Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C, 2005) |
| "To describe a patient with cyclic vomiting who was treated successfully with sumatriptan, a serotonin, agonist." | 3.69 | Sumatriptan in the treatment of cyclic vomiting. ( Benson, JM; Book, LS; Zorn, SL, 1995) |
| "Sumatriptan was administered either subcutaneously [(age x 4 + 20)/100 x 3 mg] or by nasal spray (NS; 20 mg)." | 2.76 | Sumatriptan as a treatment for cyclic vomiting syndrome: a clinical trial. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kikuchi, A; Kodama, H; Mochizuki, D; Nakamoto, N; Ogita, K, 2011) |
| "In some cases photo- and/or phonophobia (hyperexcitability) were not experienced at all, despite severe pain and nausea." | 2.72 | The natural course of migraine attacks. A prospective analysis of untreated attacks compared with attacks treated with a triptan. ( Dahlöf, C; Linde, M; Mellberg, A, 2006) |
| "The sumatriptan dose was 10 mg for a body weight of 20 to 39 kg and 20 mg for those with a body weight of >/==" BORDER="0">40 kg." | 2.71 | Nasal sumatriptan is effective in treatment of migraine attacks in children: A randomized trial. ( Ahonen, K; Hämäläinen, ML; Hoppu, K; Rantala, H, 2004) |
| "The incidence of headache recurrence was also assessed." | 2.69 | Sumatriptan nasal spray: a dose-ranging study in the acute treatment of migraine. ( Ashford, EA; Becker, WJ; Dahlof, C; Hassani, H; Peikert, A; Salonen, RJ, 1999) |
| "Three-hundred-and-twenty-eight migraine sufferers treated a first migraine attack with a nontriptan standard care medication: a mixture containing phenazone, butalbital and caffeine (optalidon) or indomethacin plus prochlorperazine plus caffeine (difmetre) or paracetamol 100 mg (tachipirine), depending on their habits." | 2.69 | Efficacy and safety of sumatriptan 50 mg in patients not responding to standard care, in the treatment of mild to moderate migraine. The Sumatriptan 50 mg Italian Study Group. ( Cavazzuti, L; Fabbri, L; Pini, LA, 1999) |
| "Oral sumatriptan 100 mg was well tolerated, and repeated administration did not alter the pattern or severity of adverse events." | 2.68 | Oral sumatriptan for the long-term treatment of migraine: clinical findings. ( Cutler, N; Hazelrigg, R; Jamerson, B; Rapoport, A; Rederich, G, 1995) |
| "Patients treated up to three migraine attacks at home over a 3-month period and recorded the results on a diary card." | 2.67 | Sumatriptan--an oral dose-defining study. The Oral Sumatriptan Dose-Defining Study Group. ( , 1991) |
| "Sumatriptan was significantly more effective than placebo in relieving headache (moderate/severe reduced to mild/none) at 2 h (50 vs." | 2.67 | Evaluation of a multiple-dose regimen of oral sumatriptan for the acute treatment of migraine. The Oral Sumatriptan International Multiple-Dose Study Group. ( , 1991) |
| "Sumatriptan was significantly more effective than Cafergot at reducing the intensity of headache from severe or moderate to mild or none; 66% (145/220) of those treated with sumatriptan improved in this way by 2 h, compared with 48% (118/246) of those treated with Cafergot (p less than 0." | 2.67 | A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Cafergot Comparative Study Group. ( , 1991) |
| "If the migraine had not improved at 1 h, patients had the option of taking a second identical injection." | 2.67 | Self-treatment of acute migraine with subcutaneous sumatriptan using an auto-injector device. The Sumatriptan Auto-Injector Study Group. ( , 1991) |
| "A similar number of patients reported migraine recurrence, within 24 h in both treatment groups." | 2.67 | A placebo-controlled study of intranasal sumatriptan for the acute treatment of migraine. The Finnish Sumatriptan Group and the Cardiovascular Clinical Research Group. ( , 1991) |
| "Migraine is a common, disabling condition and a burden for the individual, health services, and society." | 2.49 | Naproxen with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Law, S; Moore, RA, 2013) |
| "Migraine is a disabling, painful primary headache disorder that is associated with various combinations of neurological, gastrointestinal, autonomic and pain symptoms." | 2.46 | Innovative delivery systems for migraine: the clinical utility of a transdermal patch for the acute treatment of migraine. ( Freitag, F; Pearlman, SH; Rapoport, AM, 2010) |
| " Safety was evaluated based on the frequency of reported adverse events, and treatment with eASA was associated with lower incidence of adverse events than was with sumatriptan." | 2.44 | Efficacy and safety of 1,000 mg effervescent aspirin: individual patient data meta-analysis of three trials in migraine headache and migraine accompanying symptoms. ( Diener, HC; Lampl, C; Voelker, M, 2007) |
| "Cyclic vomiting syndrome is an increasingly recognized cause of nausea and vomiting in adults." | 1.36 | Adult cyclic vomiting syndrome successfully treated with intranasal sumatriptan. ( Kowalczyk, M; Parkman, H; Ward, L, 2010) |
| "The authors present a 14-year-old girl with 18q- syndrome combined with cyclic vomiting syndrome." | 1.35 | Successful treatment with sumatriptan in a case with cyclic vomiting syndrome combined with 18q- syndrome. ( Haginoya, K; Hirose, M; Kakisaka, Y; Munakata, M; Sato, I; Sato, T; Tsuchiya, S; Uematsu, M; Wakusawa, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (38.24) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 9 (26.47) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Javed, S | 1 |
| Hussain, A | 1 |
| Shah, PA | 1 |
| Raza, SA | 1 |
| Anwer, UU | 1 |
| Shamim, R | 1 |
| Rasool, F | 1 |
| Hafiz, MA | 1 |
| Bukhari, NI | 1 |
| Kirthi, V | 2 |
| Derry, S | 3 |
| Moore, RA | 3 |
| Law, S | 1 |
| Okumura, T | 1 |
| Ohhira, M | 1 |
| Kumei, S | 1 |
| Nozu, T | 1 |
| Calhoun, AH | 1 |
| Pruitt, AP | 1 |
| Kakisaka, Y | 1 |
| Wakusawa, K | 1 |
| Sato, I | 1 |
| Haginoya, K | 1 |
| Uematsu, M | 1 |
| Hirose, M | 1 |
| Munakata, M | 1 |
| Sato, T | 1 |
| Tsuchiya, S | 1 |
| Kowalczyk, M | 1 |
| Parkman, H | 1 |
| Ward, L | 1 |
| McQuay, HJ | 1 |
| Rapoport, AM | 1 |
| Freitag, F | 1 |
| Pearlman, SH | 1 |
| Hikita, T | 1 |
| Kodama, H | 1 |
| Kaneko, S | 1 |
| Amakata, K | 1 |
| Ogita, K | 1 |
| Mochizuki, D | 1 |
| Kaga, F | 1 |
| Nakamoto, N | 1 |
| Fujii, Y | 1 |
| Kikuchi, A | 1 |
| Lee, LY | 1 |
| Abbott, L | 1 |
| Mahlangu, B | 1 |
| Moodie, SJ | 1 |
| Anderson, S | 1 |
| Ahonen, K | 1 |
| Hämäläinen, ML | 1 |
| Rantala, H | 1 |
| Hoppu, K | 1 |
| Christoph-Diener, H | 1 |
| Ferrari, M | 1 |
| Mansbach, H | 1 |
| Igarashi, H | 1 |
| Cheng, FH | 1 |
| Andrews, PL | 1 |
| Moreaux, B | 1 |
| Ngan, MP | 1 |
| Rudd, JA | 1 |
| Sam, TS | 1 |
| Wai, MK | 1 |
| Wan, C | 1 |
| Winner, P | 1 |
| Rothner, AD | 1 |
| Wooten, JD | 1 |
| Webster, C | 1 |
| Ames, M | 1 |
| Linde, M | 1 |
| Mellberg, A | 1 |
| Dahlöf, C | 2 |
| Lampl, C | 1 |
| Voelker, M | 1 |
| Diener, HC | 1 |
| Nakazato, Y | 1 |
| Tamura, N | 1 |
| Shimazu, K | 1 |
| Rederich, G | 1 |
| Rapoport, A | 1 |
| Cutler, N | 1 |
| Hazelrigg, R | 1 |
| Jamerson, B | 1 |
| Hannington-Kiff, JG | 1 |
| Benson, JM | 1 |
| Zorn, SL | 1 |
| Book, LS | 1 |
| Pascual, J | 1 |
| del Arco, C | 1 |
| Romón, T | 1 |
| del Olmo, E | 1 |
| Castro, E | 1 |
| Pazos, A | 1 |
| Shane, R | 1 |
| Peikert, A | 1 |
| Becker, WJ | 1 |
| Ashford, EA | 1 |
| Hassani, H | 1 |
| Salonen, RJ | 1 |
| Pini, LA | 1 |
| Fabbri, L | 1 |
| Cavazzuti, L | 1 |
| Cipolla, G | 1 |
| Sacco, S | 1 |
| Crema, F | 1 |
| Moro, E | 1 |
| De Ponti, F | 1 |
| Frigo, G | 1 |
| Cady, R | 1 |
| Houghton, LA | 1 |
| Fowler, P | 1 |
| Keene, ON | 1 |
| Read, NW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen[NCT01522326] | 300 participants (Anticipated) | Interventional | 2012-03-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for sumatriptan and Emesis
| Article | Year |
|---|---|
Aspirin with or without an antiemetic for acute migraine headaches in adults.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Drug Therapy, Combination; Hum | 2013 |
Naproxen with or without an antiemetic for acute migraine headaches in adults.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Drug Therapy, Combination; Humans; Migr | 2013 |
Injectable sumatriptan for cyclic vomiting syndrome in adults: a case series.
Topics: Adult; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Serotonin 5-HT1 Receptor Agonis | 2014 |
Aspirin with or without an antiemetic for acute migraine headaches in adults.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Drug Therapy, Combination; Hum | 2010 |
Innovative delivery systems for migraine: the clinical utility of a transdermal patch for the acute treatment of migraine.
Topics: Clinical Trials as Topic; Drug Administration Routes; Female; Gastroparesis; Humans; Iontophoresis; | 2010 |
The management of cyclic vomiting syndrome: a systematic review.
Topics: Adrenergic beta-Antagonists; Age of Onset; Antidepressive Agents, Tricyclic; Depression; Female; Hea | 2012 |
[Side effects of triptans].
Topics: Central Nervous System; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Nause | 2004 |
Efficacy and safety of 1,000 mg effervescent aspirin: individual patient data meta-analysis of three trials in migraine headache and migraine accompanying symptoms.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relatio | 2007 |
Gastric motor effects of triptans: open questions and future perspectives.
Topics: Forecasting; Gastrointestinal Motility; Humans; Indoles; Nausea; Piperidines; Serotonin Receptor Ago | 2001 |
Almotriptan reduces the incidence of migraine-associated symptoms: a pooled analysis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials, Phase III as Topic; Female; Humans; | 2002 |
14 trials available for sumatriptan and Emesis
| Article | Year |
|---|---|
Sumatriptan as a treatment for cyclic vomiting syndrome: a clinical trial.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Male; Sumatriptan; Treatment Outcome; Vomiting; | 2011 |
Nasal sumatriptan is effective in treatment of migraine attacks in children: A randomized trial.
Topics: Administration, Intranasal; Adolescent; Child; Cross-Over Studies; Dose-Response Relationship, Drug; | 2004 |
Predicting the response to sumatriptan: the Sumatriptan Naratriptan Aggregate Patient Database.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Clinical Trials as Topic; Databases, Factual; Double-Bl | 2004 |
Sumatriptan nasal spray in adolescent migraineurs: a randomized, double-blind, placebo-controlled, acute study.
Topics: Acute Disease; Administration, Inhalation; Administration, Intranasal; Adolescent; Dose-Response Rel | 2006 |
The natural course of migraine attacks. A prospective analysis of untreated attacks compared with attacks treated with a triptan.
Topics: Adult; Aged; Comorbidity; Cross-Over Studies; Disease Progression; Female; Humans; Hyperacusis; Inci | 2006 |
Oral sumatriptan for the long-term treatment of migraine: clinical findings.
Topics: Administration, Oral; Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Lo | 1995 |
Sumatriptan nasal spray: a dose-ranging study in the acute treatment of migraine.
Topics: Adult; Aerosols; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; Humans; Hyper | 1999 |
Efficacy and safety of sumatriptan 50 mg in patients not responding to standard care, in the treatment of mild to moderate migraine. The Sumatriptan 50 mg Italian Study Group.
Topics: Adolescent; Adult; Aged; Analgesics; Double-Blind Method; Drug Resistance; Humans; Italy; Middle Age | 1999 |
Effect of sumatriptan, a new selective 5HT1-like agonist, on liquid gastric emptying in man.
Topics: Adult; Double-Blind Method; Fats; Gamma Cameras; Gastric Emptying; Half-Life; Humans; Indoles; Infus | 1992 |
Sumatriptan--an oral dose-defining study. The Oral Sumatriptan Dose-Defining Study Group.
Topics: Administration, Oral; Adult; Consumer Behavior; Double-Blind Method; Female; Humans; Indoles; Male; | 1991 |
Evaluation of a multiple-dose regimen of oral sumatriptan for the acute treatment of migraine. The Oral Sumatriptan International Multiple-Dose Study Group.
Topics: Adult; Aged; Consumer Behavior; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up | 1991 |
A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Cafergot Comparative Study Group.
Topics: Administration, Oral; Adult; Aged; Caffeine; Double-Blind Method; Drug Combinations; Electrocardiogr | 1991 |
Self-treatment of acute migraine with subcutaneous sumatriptan using an auto-injector device. The Sumatriptan Auto-Injector Study Group.
Topics: Adult; Aged; Consumer Behavior; Double-Blind Method; Female; Humans; Indoles; Injections, Subcutaneo | 1991 |
A placebo-controlled study of intranasal sumatriptan for the acute treatment of migraine. The Finnish Sumatriptan Group and the Cardiovascular Clinical Research Group.
Topics: Absorption; Administration, Intranasal; Adult; Disability Evaluation; Double-Blind Method; Female; H | 1991 |
10 other studies available for sumatriptan and Emesis
| Article | Year |
|---|---|
Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization.
Topics: Excipients; Humans; Migraine Disorders; Nausea; Prochlorperazine; Sumatriptan; Vomiting | 2022 |
An adult patient with cyclic vomiting syndrome successfully treated with oral sumatriptan.
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 2014 |
Successful treatment with sumatriptan in a case with cyclic vomiting syndrome combined with 18q- syndrome.
Topics: Administration, Intranasal; Adolescent; Adrenal Cortex; Brain; Chromosome Disorders; Chromosomes, Hu | 2009 |
Adult cyclic vomiting syndrome successfully treated with intranasal sumatriptan.
Topics: Administration, Intranasal; Age Factors; Humans; Male; Middle Aged; Periodicity; Sumatriptan; Syndro | 2010 |
Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Butanols; Capsaicin; Cyclooxygenase Inhibitors; Dihydroergotamine; Diphenhydra | 2005 |
An adult case of cyclic vomiting syndrome successfully responding to valproic acid.
Topics: Anti-Anxiety Agents; Anticonvulsants; Antiemetics; Consciousness Disorders; Diazepam; Female; Humans | 2008 |
Sumatriptan relieves and prevents peri-operative migraine attacks.
Topics: Adult; Anesthesia, General; Female; Humans; Indoles; Middle Aged; Migraine Disorders; Postoperative | 1993 |
Sumatriptan in the treatment of cyclic vomiting.
Topics: Abdominal Pain; Adult; Humans; Male; Nausea; Recurrence; Serotonin Receptor Agonists; Sumatriptan; V | 1995 |
Autoradiographic distribution of [3H]sumatriptan-binding sites in post-mortem human brain.
Topics: Adult; Animals; Antiemetics; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Mapping; Guinea Pigs | 1996 |
Development and implementation of practice guidelines (Part 1).
Topics: Acquired Immunodeficiency Syndrome; Colony-Stimulating Factors; Drug Utilization; Hospital Bed Capac | 1994 |