sumatriptan has been researched along with Dyspepsia in 10 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Dyspepsia: Impaired digestion, especially after eating.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most people who experience migraine use OTC medications to treat their symptoms, but no head-to-head clinical trials comparing these agents with prescription migraine therapies have been published." | 2.71 | Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial. ( Baggish, J; Battikha, JP; Elkind, AH; Gallagher, RM; Goldstein, J; Hoffman, H; Saper, JR; Silberstein, SD; Smith, TR, 2005) |
| "Pretreatment with sumatriptan is able to restore impaired accommodation and to improve early satiety in patients with functional dyspepsia." | 2.41 | The physiology and the pathophysiology of the gastric accommodation reflex in man. ( Tack, J, 2000) |
| "Pretreatment with sumatriptan increased both pressures and volumes needed to induce first perception and discomfort." | 1.32 | Role of tension receptors in dyspeptic patients with hypersensitivity to gastric distention. ( Caenepeel, P; Corsetti, M; Janssens, J; Tack, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 9 (90.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malatesta, MG | 1 |
| Fascetti, E | 1 |
| Ciccaglione, AF | 1 |
| Cappello, G | 1 |
| Grossi, L | 1 |
| Ferri, A | 1 |
| Marzio, L | 1 |
| Tack, J | 6 |
| Caenepeel, P | 4 |
| Piessevaux, H | 2 |
| Cuomo, R | 1 |
| Janssens, J | 5 |
| Moro, E | 1 |
| Crema, F | 1 |
| De Ponti, F | 1 |
| Frigo, G | 1 |
| Corsetti, M | 1 |
| Goldstein, J | 1 |
| Silberstein, SD | 1 |
| Saper, JR | 1 |
| Elkind, AH | 1 |
| Smith, TR | 1 |
| Gallagher, RM | 1 |
| Battikha, JP | 1 |
| Hoffman, H | 1 |
| Baggish, J | 1 |
| Coulie, B | 1 |
| Vingerhagen, S | 1 |
| Hausken, T | 1 |
| Gilja, OH | 1 |
| Berstad, A | 1 |
| Sarnelli, G | 1 |
| Demedts, I | 1 |
| Dehondt, G | 1 |
| Fischler, B | 1 |
| Zandecki, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of a Low FODMAP Diet in Functional Dyspepsia Patients With Meal Related Symptoms on Complaint Pattern and Urinary Histamine Excretion[NCT05832528] | 30 participants (Anticipated) | Interventional | 2022-10-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sumatriptan and Dyspepsia
| Article | Year |
|---|---|
Triptans and gastric accommodation: pharmacological and therapeutic aspects.
Topics: Animals; Disease Models, Animal; Dyspepsia; Gastric Acidity Determination; Gastric Emptying; Humans; | 2004 |
The physiology and the pathophysiology of the gastric accommodation reflex in man.
Topics: Adaptation, Physiological; Animals; Appetite; Dyspepsia; Gastric Emptying; Humans; Muscle Contractio | 2000 |
5 trials available for sumatriptan and Dyspepsia
| Article | Year |
|---|---|
5-HT1-receptor agonist sumatriptan modifies gastric size after 500 ml of water in dyspeptic patients and normal subjects.
Topics: Adult; Dyspepsia; Female; Humans; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Radiography; | 2002 |
Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia.
Topics: Adult; Analysis of Variance; Case-Control Studies; Cisapride; Cross-Over Studies; Double-Blind Metho | 2003 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non- | 2005 |
Influence of a 5HT1 receptor agonist on gastric accommodation and initial transpyloric flow in healthy subjects.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Dyspepsia; Female; Gastric Emptying; Humans; Male; P | 2000 |
Effect of intranasal sumatriptan on gastric tone and sensitivity to distension.
Topics: Administration, Intranasal; Adult; Cross-Over Studies; Double-Blind Method; Dyspepsia; Female; Human | 2001 |
3 other studies available for sumatriptan and Dyspepsia
| Article | Year |
|---|---|
Role of tension receptors in dyspeptic patients with hypersensitivity to gastric distention.
Topics: Adult; Clonidine; Dyspepsia; Female; Gastric Dilatation; Humans; Male; Mechanoreceptors; Perception; | 2004 |
Role of impaired gastric accommodation to a meal in functional dyspepsia.
Topics: Adult; Dyspepsia; Eating; Female; Humans; Male; Multivariate Analysis; Satiation; Serotonin Receptor | 1998 |
Clinical and pathophysiological characteristics of acute-onset functional dyspepsia.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Amyl Nitrite; Dyspepsia; Enzyme Inhibitors | 2002 |