Page last updated: 2024-11-04

sumatriptan and Depressive Disorder

sumatriptan has been researched along with Depressive Disorder in 13 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
"Patients with a history of migraine occasionally have similar headaches precipitated by ECT."1.29Sumatriptan prophylaxis for postelectroconvulsive therapy headaches. ( DeBattista, C; Mueller, K, 1995)
" Because sumatriptan does not appear to cross the blood-brain barrier and has a short half-life, it was deemed relatively safe to prescribe sumatriptan with antidepressant treatments."1.29The safety of concomitant use of sumatriptan and antidepressant treatments. ( Bergeron, R; Blier, P, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (69.23)18.2507
2000's4 (30.77)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Finfgeld, DL1
GĂ©raud, G1
Mahmood, T1
Silverstone, T1
Sussman, N1
DeBattista, C1
Mueller, K1
LaPorta, LD1
Blier, P1
Bergeron, R1
Szabo, CP1
Yatham, LN1
Zis, AP1
Lam, RW1
Tam, E1
Shiah, IS1
Cleare, AJ1
Murray, RM1
Sherwood, RA1
O'Keane, V1
Fantz, RM1
Markowitz, JS1
Kellner, CH1
Schwartz, CE1
Berk, M1
Stein, DJ1
Potgieter, A1
Maud, CM1
Els, C1
Janet, ML1
Viljoen, E1

Reviews

3 reviews available for sumatriptan and Depressive Disorder

ArticleYear
Serotonin syndrome and the use of SSRIs.
    Journal of psychosocial nursing and mental health services, 2004, Volume: 42, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Therapy, Combination; Fem

2004
[Therapeutic recommendations for migraine].
    Soins; la revue de reference infirmiere, 2004, Issue:690

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Anxiety Disorders; Biofeedback, Psychology; Com

2004
The potential benefits of serotonin receptor-specific agents.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Humans; Isoxazoles; Ondansetron; Piperazines;

1994

Trials

3 trials available for sumatriptan and Depressive Disorder

ArticleYear
Neuroendocrine challenge with a 5-HT(1D) receptor agonist differentiates between two subtypes of bipolar disorder according to polarity of onset.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:1

    Topics: Bipolar Disorder; Depressive Disorder; Diagnosis, Differential; Humans; Psychiatric Status Rating Sc

2005
Sumatriptan-induced growth hormone release in patients with major depression, mania, and normal controls.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 17, Issue:4

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Growth Hormone; Humans; Male; Psychiatric Stat

1997
Serotonergic targets in the treatment of antidepressant induced sexual dysfunction: a pilot study of granisetron and sumatriptan.
    International clinical psychopharmacology, 2000, Volume: 15, Issue:5

    Topics: Adult; Antidepressive Agents; Cross-Over Studies; Depressive Disorder; Female; Granisetron; Humans;

2000

Other Studies

7 other studies available for sumatriptan and Depressive Disorder

ArticleYear
Sumatriptan prophylaxis for postelectroconvulsive therapy headaches.
    Headache, 1995, Volume: 35, Issue:8

    Topics: Adult; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Migraine Disorders; Premedica

1995
Recurrent depression after sumatriptan administration for treatment of migraine.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:1

    Topics: Depressive Disorder; Female; Humans; Middle Aged; Migraine Disorders; Recurrence; Sumatriptan

1995
The safety of concomitant use of sumatriptan and antidepressant treatments.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:2

    Topics: Administration, Oral; Adult; Antidepressive Agents; Contraindications; Depressive Disorder; Drug The

1995
Fluoxetine and sumatriptan: possibly a counterproductive combination.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:1

    Topics: Acute Disease; Adult; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Flu

1995
Abnormal 5-HT1D receptor function in major depression: a neuropharmacological challenge study using sumatriptan.
    Psychological medicine, 1998, Volume: 28, Issue:2

    Topics: Adult; Case-Control Studies; Depressive Disorder; Female; Growth Hormone; Humans; Male; Prolactin; R

1998
Sumatriptan for post-ECT headache.
    The journal of ECT, 1998, Volume: 14, Issue:4

    Topics: Administration, Oral; Adult; Depressive Disorder; Electroconvulsive Therapy; Female; Headache; Human

1998
A surfeit of serotonin: sumatriptan and serotonergic antidepressants.
    Archives of internal medicine, 1999, May-24, Volume: 159, Issue:10

    Topics: Antidepressive Agents, Second-Generation; Colitis; Depressive Disorder; Drug Synergism; Fluoxetine;

1999