Page last updated: 2024-11-04

sumatriptan and Coronary Vasospasm

sumatriptan has been researched along with Coronary Vasospasm in 18 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.

Research Excerpts

ExcerptRelevanceReference
"The aim of this review is to describe: the mechanisms of action of triptans; the case-reports of acute myocardial infarction (AMI) associated with sumatriptan use; and the results of studies evaluating its tolerability and safety."8.86Sumatriptan therapy for headache and acute myocardial infarction. ( Ames, PR; Barra, S; Gaeta, G; Lanero, S; Madrid, A; Materazzi, C; Vitagliano, G, 2010)
"We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases."7.75Acute myocardial infarction with sumatriptan: a case report and review of the literature. ( Chalaupka, FD, 2009)
"The aim of this review is to describe: the mechanisms of action of triptans; the case-reports of acute myocardial infarction (AMI) associated with sumatriptan use; and the results of studies evaluating its tolerability and safety."4.86Sumatriptan therapy for headache and acute myocardial infarction. ( Ames, PR; Barra, S; Gaeta, G; Lanero, S; Madrid, A; Materazzi, C; Vitagliano, G, 2010)
" Sumatriptan, a medication usually prescribed for acute migraine and cluster headaches has been documented as potentially causing coronary vasospasm, thereby leading to MI."3.96Vasospasm induced myocardial ischaemia secondary to sumatriptan use. ( Ojha, U; Okonkwo, K, 2020)
"We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases."3.75Acute myocardial infarction with sumatriptan: a case report and review of the literature. ( Chalaupka, FD, 2009)
"Part 1 discusses the risks for Torsade de Pointes, vasospasm, and ischemia, with a review and discussion of case reports of triptan-associated cardiovascular events in migraineurs with and without CAD risk factors or documented CAD; of the epidemiology and studies of triptans, vasospasm, and cardiovascular morbidity; and of the relationship of variant angina, migraine, and vasospastic disease."2.49QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, and headache medications. Part 1: review of serotonergic cardiac adverse events with a triptan case. ( Cho, L; Stillman, MJ; Tepper, DE; Tepper, S, 2013)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (61.11)18.2507
2000's3 (16.67)29.6817
2010's2 (11.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Vandebosch, C1
Dupont, M1
Verhaert, D1
Mullens, W1
Okonkwo, K1
Ojha, U1
Chalaupka, FD1
Barra, S1
Lanero, S1
Madrid, A1
Materazzi, C1
Vitagliano, G1
Ames, PR1
Gaeta, G1
Stillman, MJ1
Tepper, S1
Tepper, DE1
Cho, L1
Bassi, S1
Amersey, R1
Henderson, R1
Morris, GK1
Shimizu, M1
Hata, K1
Takaoka, H1
Kanazawa, K1
Shinke, T1
Matsumoto, H1
Watanabe, S1
Yoshikawa, R1
Masai, H1
Miyamoto, Y1
Akita, H1
Yokoyama, M1
Palmer, J1
Feldman, R1
Mancini, GB1
Zimmerman, M1
Walton-Shirley, M1
Flowers, K1
Whiteside, JH1
Lippolis, A1
Castini, D1
Cirino, D1
Ornaghi, M1
Peters, RH1
Meyburg, HW1
Westendorp, PH1
Westerhof, PW1
MacLean, MR1
Smith, GC1
Templeton, AG1
Mueller, L1
Gallagher, RM1
Ciervo, CA1
Porter, LM1
Deleu, D1
Hanssens, Y1
Willett, F1
Curzen, N1
Adams, J1
Armitage, M1
Castle, WM1
Simmons, VE2
Lloyd, DK1
Pilgrim, AJ1

Reviews

3 reviews available for sumatriptan and Coronary Vasospasm

ArticleYear
Sumatriptan therapy for headache and acute myocardial infarction.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:16

    Topics: Adolescent; Adult; Animals; Coronary Vasospasm; Female; Humans; Male; Middle Aged; Migraine Disorder

2010
QT prolongation, Torsade de Pointes, myocardial ischemia from coronary vasospasm, and headache medications. Part 1: review of serotonergic cardiac adverse events with a triptan case.
    Headache, 2013, Volume: 53, Issue:1

    Topics: Coronary Vasospasm; Electrocardiography; Female; Humans; Middle Aged; Migraine Disorders; Myocardial

2013
Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.
    Acta neurologica Belgica, 1999, Volume: 99, Issue:2

    Topics: Acute Disease; Animals; Clinical Trials as Topic; Coronary Circulation; Coronary Vasospasm; Drug Des

1999

Trials

2 trials available for sumatriptan and Coronary Vasospasm

ArticleYear
Glyceryl trinitrate reversal of post-sumatriptan coronary artery narrowing.
    Lancet (London, England), 1995, May-27, Volume: 345, Issue:8961

    Topics: Coronary Angiography; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Humans; Injections, In

1995
Coronary vasospasm and sumatriptan.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: Chest Pain; Coronary Vasospasm; Humans; Indoles; Sulfonamides; Sumatriptan; Vasoconstrictor Agents

1992

Other Studies

13 other studies available for sumatriptan and Coronary Vasospasm

ArticleYear
Severe coronary artery spasm after administration of a 5-hydroxytryptamine type 1 receptor agonist in a patient with new-onset Graves' disease and myocarditis after SARS-CoV2 vaccination.
    Acta cardiologica, 2023, Volume: 78, Issue:8

    Topics: 2019-nCoV Vaccine mRNA-1273; Coronary Vasospasm; COVID-19; COVID-19 Vaccines; Graves Disease; Humans

2023
Vasospasm induced myocardial ischaemia secondary to sumatriptan use.
    BMJ case reports, 2020, Aug-24, Volume: 13, Issue:8

    Topics: Coronary Angiography; Coronary Vasospasm; Electrocardiography; Humans; Male; Middle Aged; Migraine D

2020
Acute myocardial infarction with sumatriptan: a case report and review of the literature.
    Headache, 2009, Volume: 49, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aspirin; Coronary Vasospasm; Coronary Vessels; Echocardi

2009
Thyrotoxicosis, sumatriptan and coronary artery spasm.
    Journal of the Royal Society of Medicine, 2004, Volume: 97, Issue:6

    Topics: Coronary Angiography; Coronary Vasospasm; Female; Heart Arrest; Humans; Middle Aged; Migraine Disord

2004
Sumatriptan provokes coronary artery spasm in patients with variant angina: possible involvement of serotonin 1B receptor.
    International journal of cardiology, 2007, Jan-08, Volume: 114, Issue:2

    Topics: Adult; Angina Pectoris, Variant; Coronary Vasospasm; Coronary Vessels; Female; Humans; Male; Middle

2007
Unstable angina pectoris associated with Imitrex therapy.
    Catheterization and cardiovascular diagnosis, 1995, Volume: 34, Issue:2

    Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Coronary Vasospasm; Electrocardiography; Female; H

1995
[Coronary vasospasm secondary to subcutaneous administration of sumatriptan].
    Giornale italiano di cardiologia, 1994, Volume: 24, Issue:7

    Topics: Adult; Coronary Angiography; Coronary Vasospasm; Diagnosis, Differential; Echocardiography; Female;

1994
[Use of sumatriptan (Imigran) in a female patient with coronary spasm].
    Nederlands tijdschrift voor geneeskunde, 1994, Sep-10, Volume: 138, Issue:37

    Topics: Adult; Coronary Angiography; Coronary Vasospasm; Ergotamine; Female; Humans; Migraine Disorders; Sum

1994
Adverse reactions associated with sumatriptan.
    Lancet (London, England), 1993, Apr-24, Volume: 341, Issue:8852

    Topics: Coronary Vasospasm; Drug Interactions; Humans; Indoles; Nitric Oxide; Serotonin Receptor Agonists; S

1993
Vasospasm-induced myocardial infarction with sumatriptan.
    Headache, 1996, Volume: 36, Issue:5

    Topics: Coronary Vasospasm; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Migraine Disorders;

1996
What's causing angina in this headache patient?
    RN, 1998, Volume: 61, Issue:10

    Topics: Adult; Angina Pectoris; Coronary Vasospasm; Humans; Male; Migraine Disorders; Sumatriptan; Vasoconst

1998
Coronary vasospasm induced by subcutaneous sumatriptan.
    BMJ (Clinical research ed.), 1992, May-30, Volume: 304, Issue:6839

    Topics: Coronary Vasospasm; Humans; Indoles; Injections, Subcutaneous; Male; Middle Aged; Sulfonamides; Suma

1992
Coronary vasospasm and sumatriptan.
    BMJ (Clinical research ed.), 1992, Jul-11, Volume: 305, Issue:6845

    Topics: Coronary Vasospasm; Humans; Indoles; Sulfonamides; Sumatriptan

1992