sumatriptan has been researched along with Coronary Heart Disease in 10 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sumatriptan has a weak coronary constrictor effect." | 5.29 | [The migraine remedy sumatriptan (Imigran) and coronary heart disease]. ( Landmark, K; Nguyen, KN, 1995) |
| "Triptans, 5-HT1B/1D agonists used in migraine treatment, are rarely involved in serious coronary events due to vasospasm." | 2.41 | [Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause]. ( Hedenmalm, K, 2000) |
| "Sumatriptan has a weak coronary constrictor effect." | 1.29 | [The migraine remedy sumatriptan (Imigran) and coronary heart disease]. ( Landmark, K; Nguyen, KN, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palmer, J | 1 |
| Feldman, R | 1 |
| Mancini, GB | 1 |
| Zimmerman, M | 1 |
| Nguyen, KN | 1 |
| Landmark, K | 1 |
| Kelly, KM | 1 |
| Kaumann, AJ | 1 |
| Frenken, M | 1 |
| Posival, H | 1 |
| Brown, AM | 1 |
| Lloyd, DK | 1 |
| Simmons, V | 1 |
| Grundemar, L | 1 |
| Maassen VanDenBrink, A | 1 |
| Bax, WA | 1 |
| Ramrattan, NN | 1 |
| Ferrari, MD | 1 |
| Saxena, PR | 1 |
| Hedenmalm, K | 1 |
| Turner, P | 1 |
2 reviews available for sumatriptan and Coronary Heart Disease
| Article | Year |
|---|---|
[Sumatriptan and cardiac complaints. Careful cardiac anamnesis is needed prior to treatment].
Topics: Cardiovascular Diseases; Coronary Disease; Humans; Migraine Disorders; Sumatriptan | 1994 |
[Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause].
Topics: Contraindications; Coronary Disease; Humans; Migraine Disorders; Myocardial Infarction; Risk Assessm | 2000 |
1 trial available for sumatriptan and Coronary Heart Disease
| Article | Year |
|---|---|
Glyceryl trinitrate reversal of post-sumatriptan coronary artery narrowing.
Topics: Coronary Angiography; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Humans; Injections, In | 1995 |
7 other studies available for sumatriptan and Coronary Heart Disease
| Article | Year |
|---|---|
[The migraine agent sumatriptan (Imigran) and coronary heart disease].
Topics: Contraindications; Coronary Disease; Humans; Sumatriptan | 1995 |
[The migraine remedy sumatriptan (Imigran) and coronary heart disease].
Topics: Adult; Angina Pectoris; Coronary Disease; Female; Humans; Migraine Disorders; Risk Factors; Sumatrip | 1995 |
Cardiac arrest following use of sumatriptan.
Topics: Adult; Coronary Disease; Female; Heart Arrest; Humans; Migraine Disorders; Sumatriptan | 1995 |
Variable participation of 5-HT1-like receptors and 5-HT2 receptors in serotonin-induced contraction of human isolated coronary arteries. 5-HT1-like receptors resemble cloned 5-HT1D beta receptors.
Topics: Adult; Arteriosclerosis; Binding, Competitive; Cardiomyopathy, Dilated; Cloning, Molecular; Coronary | 1994 |
Adverse reactions associated with sumatriptan.
Topics: Contraindications; Coronary Disease; Humans; Indoles; Myocardial Infarction; Serotonin Receptor Agon | 1993 |
Human isolated coronary artery contraction to sumatriptan: a post hoc analysis.
Topics: Adult; Aged; Cause of Death; Chest Pain; Contraindications; Coronary Disease; Coronary Vessels; Dise | 1999 |
Migraine.
Topics: Coronary Disease; Humans; Indoles; Migraine Disorders; Sulfonamides; Sumatriptan; Vasoconstrictor Ag | 1992 |