sumatriptan has been researched along with Coronary Artery Disease in 4 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The triptans, serotonin 5-HT(1B/1D) receptor agonists exemplified by sumatriptan, are a mainstay migraine therapy but have class labeling contraindicating their use in patients with coronary artery disease." | 3.75 | Effects of the prototype serotonin 5-HT(1B/1D) receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP(8-37) on myocardial reactive hyperemic response in conscious dogs. ( Anderson, KD; Gould, RJ; Kane, SA; Koblan, KS; Lynch, JJ; Pittman, TJ; Regan, CP; Shen, YT, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lynch, JJ | 1 |
| Shen, YT | 1 |
| Pittman, TJ | 1 |
| Anderson, KD | 1 |
| Koblan, KS | 1 |
| Gould, RJ | 1 |
| Regan, CP | 1 |
| Kane, SA | 1 |
| Shaffer, CR | 1 |
| Edvinsson, L | 1 |
| Uddman, E | 1 |
| Wackenfors, A | 1 |
| Davenport, A | 1 |
| Longmore, J | 1 |
| Malmsjö, M | 1 |
| Newman, CM | 1 |
| Starkey, I | 1 |
| Buller, N | 1 |
| Seabra-Gomes, R | 1 |
| Kirby, S | 1 |
| Hettiarachchi, J | 1 |
| Cumberland, D | 1 |
| Hillis, WS | 1 |
1 trial available for sumatriptan and Coronary Artery Disease
| Article | Year |
|---|---|
Effects of sumatriptan and eletriptan on diseased epicardial coronary arteries.
Topics: Adult; Aged; Angiography; Angioplasty, Balloon, Coronary; Coronary Artery Disease; Coronary Vessels; | 2005 |
3 other studies available for sumatriptan and Coronary Artery Disease
| Article | Year |
|---|---|
Effects of the prototype serotonin 5-HT(1B/1D) receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP(8-37) on myocardial reactive hyperemic response in conscious dogs.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cath | 2009 |
Triptan therapy in migraine.
Topics: Adult; Coronary Artery Disease; Electrocardiography; Female; Humans; Injections, Subcutaneous; Migra | 2010 |
Triptan-induced contractile (5-HT1B receptor) responses in human cerebral and coronary arteries: relationship to clinical effect.
Topics: Adult; Cerebral Arteries; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Dru | 2005 |