Page last updated: 2024-11-04

sumatriptan and Complications, Pregnancy

sumatriptan has been researched along with Complications, Pregnancy in 12 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Research Excerpts

ExcerptRelevanceReference
" A systematic review of the medical literature was conducted to identify information regarding the safety of sumatriptan during pregnancy."8.82Safety of sumatriptan in pregnancy: a review of the data so far. ( Loder, E, 2003)
"To evaluate delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan."7.71Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan. ( Källén, B; Lygner, PE, 2001)
"5% of fertile Danish women use sumatriptan, and the drug is also taken during pregnancy."7.70Pregnancy outcome following prescription for sumatriptan. ( Nielsen, GL; Olesen, C; Olsen, J; Sorensen, HT; Steffensen, FH, 2000)
" A systematic review of the medical literature was conducted to identify information regarding the safety of sumatriptan during pregnancy."4.82Safety of sumatriptan in pregnancy: a review of the data so far. ( Loder, E, 2003)
"Using the Marketscan database, the risk of major birth defects was ascertained in live-born infants whose birth mothers were exposed to sumatriptan, naratriptan, or sumatriptan/naproxen during pregnancy."3.88Use of existing electronic health care databases to evaluate medication safety in pregnancy: Triptan exposure in pregnancy as a case study. ( Bollinger, L; Cangialose, C; Chia, V; Mikol, DD; Xue, F; Yusuf, A, 2018)
"Accumulated data suggest that exposure to sumatriptan during pregnancy does not increase the risk of birth defects above the baseline rate."3.76Safety of triptans for migraine headaches during pregnancy and breastfeeding. ( Bozzo, P; Duong, S; Einarson, A; Nordeng, H, 2010)
"To evaluate delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan."3.71Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan. ( Källén, B; Lygner, PE, 2001)
" The proportions of outcomes with birth defects are as follows: in the Acyclovir (antiviral medication) Pregnancy Registry (1984-1998) (19/581), 3."3.70Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment. ( Andrews, EB; Ephross, SA; Heffner, CR; Reiff-Eldridge, R; Tennis, PS; White, AD, 2000)
"5% of fertile Danish women use sumatriptan, and the drug is also taken during pregnancy."3.70Pregnancy outcome following prescription for sumatriptan. ( Nielsen, GL; Olesen, C; Olsen, J; Sorensen, HT; Steffensen, FH, 2000)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jarvis, S1
Dassan, P1
Piercy, CN1
Yusuf, A1
Chia, V1
Xue, F1
Mikol, DD1
Bollinger, L1
Cangialose, C1
Hultzsch, S1
Schaefer, C1
Duong, S1
Bozzo, P1
Nordeng, H1
Einarson, A1
Williams, SH1
Kehr, HA1
Loder, E1
Fox, AW1
Reiff-Eldridge, R1
Heffner, CR1
Ephross, SA1
Tennis, PS1
White, AD1
Andrews, EB1
Olesen, C2
Steffensen, FH1
Sorensen, HT1
Nielsen, GL1
Olsen, J2
Källén, B1
Lygner, PE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Sumatriptan and Naratriptan Pregnancy Registry[NCT01059604]868 participants (Actual)Observational [Patient Registry]2001-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for sumatriptan and Complications, Pregnancy

ArticleYear
Migraine and pregnancy. Choice of treatment.
    Prescrire international, 2014, Volume: 23, Issue:153

    Topics: Abnormalities, Drug-Induced; Female; Fetus; Gestational Age; Humans; Migraine Disorders; Patient Sel

2014
[Analgesic drugs during pregnancy].
    Schmerz (Berlin, Germany), 2016, Volume: 30, Issue:6

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa

2016
An update in the treatment of neurologic disorders during pregnancy--focus on migraines and seizures.
    Journal of pharmacy practice, 2012, Volume: 25, Issue:3

    Topics: Animals; Anticonvulsants; Female; Humans; Migraine Disorders; Nervous System Diseases; Pregnancy; Pr

2012
Safety of sumatriptan in pregnancy: a review of the data so far.
    CNS drugs, 2003, Volume: 17, Issue:1

    Topics: Animals; Female; Humans; Migraine Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome;

2003

Other Studies

8 other studies available for sumatriptan and Complications, Pregnancy

ArticleYear
Managing migraine in pregnancy.
    BMJ (Clinical research ed.), 2018, 01-25, Volume: 360

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Female; Humans; Migraine with Aura; Pre

2018
Use of existing electronic health care databases to evaluate medication safety in pregnancy: Triptan exposure in pregnancy as a case study.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:12

    Topics: Abnormalities, Drug-Induced; Administrative Claims, Healthcare; Adolescent; Adult; Databases, Factua

2018
Safety of triptans for migraine headaches during pregnancy and breastfeeding.
    Canadian family physician Medecin de famille canadien, 2010, Volume: 56, Issue:6

    Topics: Breast Feeding; Female; Humans; Migraine Disorders; Piperidines; Pregnancy; Pregnancy Complications;

2010
Revised estimates for probability of successful outcome of pregnancy after sumatriptan exposure.
    Headache, 2004, Volume: 44, Issue:3

    Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Migraine Disorders; Pregnancy; Pregnan

2004
Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment.
    American journal of obstetrics and gynecology, 2000, Volume: 182, Issue:1 Pt 1

    Topics: Abnormalities, Drug-Induced; Acyclovir; Anticonvulsants; Antiviral Agents; Drug Industry; Epilepsy;

2000
Pregnancy outcome following prescription for sumatriptan.
    Headache, 2000, Volume: 40, Issue:1

    Topics: Adult; Drug Prescriptions; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Maternal Expos

2000
Sumatriptan: what do we know about fetal risks?
    Headache, 2001, Volume: 41, Issue:2

    Topics: Denmark; Female; Humans; Infant, Newborn; Infant, Premature; Maternal Exposure; Migraine Disorders;

2001
Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan.
    Headache, 2001, Volume: 41, Issue:4

    Topics: Adult; Congenital Abnormalities; Delivery, Obstetric; Female; Humans; Infant, Newborn; Middle Aged;

2001