sumatriptan has been researched along with Chronic Pain in 5 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ipsilateral, but not contralateral, pre-treatment (in μg/paw) with sumatriptan (10-300), methysergide (1-30) or dihydroergotamine (1-30) significantly prevented flinching behavior (at 1h) as well as secondary allodynia and hyperalgesia (at day 6) induced by formalin." | 3.79 | Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats. ( Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM, 2013) |
| "The prolongation of PGE2 hyperalgesia was also permanently reversed by intradermal injection of cordycepin, a protein translation inhibitor." | 1.43 | Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming. ( Araldi, D; Ferrari, LF; Levine, JD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, C | 1 |
| Unekawa, M | 1 |
| Kitagawa, S | 1 |
| Takizawa, T | 1 |
| Kayama, Y | 1 |
| Nakahara, J | 1 |
| Shibata, M | 1 |
| Godínez-Chaparro, B | 1 |
| López-Santillán, FJ | 1 |
| Argüelles, CF | 1 |
| Villalón, CM | 1 |
| Granados-Soto, V | 1 |
| Leone, M | 1 |
| Proietti Cecchini, A | 1 |
| Araldi, D | 1 |
| Ferrari, LF | 1 |
| Levine, JD | 1 |
| Hultzsch, S | 1 |
| Schaefer, C | 1 |
1 review available for sumatriptan and Chronic Pain
| Article | Year |
|---|---|
[Analgesic drugs during pregnancy].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa | 2016 |
4 other studies available for sumatriptan and Chronic Pain
| Article | Year |
|---|---|
Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cere | 2020 |
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Dr | 2013 |
Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache.
Topics: Adult; Aged; Chronic Pain; Cluster Headache; Drug Resistance; Female; Humans; Injections, Subcutaneo | 2016 |
Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming.
Topics: Animals; Chronic Pain; Female; Hyperalgesia; Male; Nociceptors; Pain Threshold; Rats; Rats, Sprague- | 2016 |