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sumatriptan and Chest Pain

sumatriptan has been researched along with Chest Pain in 26 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Chest Pain: Pressure, burning, or numbness in the chest.

Research Excerpts

ExcerptRelevanceReference
"In order to assess whether chest pain attributed to sumatriptan is associated with abnormalities on cardiac exercise testing, we performed a case-control study."9.08Exercise testing in patients with chest pain to sumatriptan. ( Grobbee, DE; Hoorntje, JC; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1998)
"Patients without cardiac risk factors may experience myocardial infarction following an oral dose of sumatriptan."7.72Oral sumatriptan-induced myocardial infarction. ( Hack, JB, 2004)
" Thus, the cost of chest pain-related care was estimated in migraineurs receiving almotriptan 12."7.71Impact of chest pain on cost of migraine treatment with almotriptan and sumatriptan. ( Barr, CE; Goldfarb, SD; Wang, JT, 2002)
"A total of 137 patients with chest pain associated with intake of sumatriptan were identified and compared with 229 consumers of sumatriptan without this adverse reaction."7.69Characteristics and determinants of sumatriptan-associated chest pain. ( Grobbee, DE; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1997)
"In order to assess whether chest pain attributed to sumatriptan is associated with abnormalities on cardiac exercise testing, we performed a case-control study."5.08Exercise testing in patients with chest pain to sumatriptan. ( Grobbee, DE; Hoorntje, JC; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1998)
"Patients without cardiac risk factors may experience myocardial infarction following an oral dose of sumatriptan."3.72Oral sumatriptan-induced myocardial infarction. ( Hack, JB, 2004)
" An economic model was constructed to estimate annual cost savings per 1,000 patients receiving almotriptan instead of sumatriptan as a function of differing rates of chest pain."3.71Cost savings in migraine associated with less chest pain on new triptan therapy. ( Barr, CE; Goldfarb, SD; Rowland, CR; Torigoe, Y; Wang, E; Wang, JT, 2002)
" Thus, the cost of chest pain-related care was estimated in migraineurs receiving almotriptan 12."3.71Impact of chest pain on cost of migraine treatment with almotriptan and sumatriptan. ( Barr, CE; Goldfarb, SD; Wang, JT, 2002)
"A total of 137 patients with chest pain associated with intake of sumatriptan were identified and compared with 229 consumers of sumatriptan without this adverse reaction."3.69Characteristics and determinants of sumatriptan-associated chest pain. ( Grobbee, DE; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1997)
" Forty-five patients (88%) reported at least one adverse event and 23 (45%) experienced pressure, tightness, and/or pain in the chest, neck, and/or throat after administration of avitriptan."2.69Safety trial with the 5HT1B/1D agonist avitriptan (BMS-180048) in patients with migraine who have experienced pressure, tightness, and/or pain in the chest, neck, and/or throat following sumatriptan. ( Dahlöf, CG; Falk, L; Lewis, CP; Risenfors, M, 1998)
"Their clinical diagnoses were migraine with aura, migraine without aura, cluster headache, and others."1.31Evidence against strong correlation between chest symptoms and ischemic coronary changes after subcutaneous sumatriptan injection. ( Endo, M; Igarashi, H; Sakai, F; Suzuki, N; Tomita, M, 2002)
"Sumatriptan was used by 453 patients, during 25 months (median), for 28000 attacks (median: 33 attacks/patient)."1.29Chest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patients. ( de Vriend, RH; Ferrari, MD; Jaspers, NM; Visser, WH, 1996)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (69.23)18.2507
2000's8 (30.77)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirata, K1
Tomita, M1
Suzuki, N1
Igarashi, H1
Endo, M1
Sakai, F1
Richardson, MS1
Bowers, BW1
Petrie, JL1
Hack, JB1
Hood, S1
Birnie, D1
MacIntyre, PD3
Hillis, WS3
Ottervanger, JP5
van Witsen, TB2
Valkenburg, HA4
Grobbee, DE3
Stricker, BH5
Houghton, LA1
Foster, JM1
Whorwell, PJ1
Morris, J1
Fowler, P1
McKirdy, HC1
Lowndes, RH1
Boyd, IW1
Rohan, AP1
Loi, V1
Lai, M1
Pisano, MR1
Del Zompo, M1
Visser, WH1
Jaspers, NM1
de Vriend, RH1
Ferrari, MD2
Dahlöf, CG2
Mathew, N1
Falk, L1
Risenfors, M1
Lewis, CP1
Hoorntje, JC1
Maassen VanDenBrink, A1
Bax, WA1
Ramrattan, NN1
Saxena, PR1
Bennett, J1
Wang, JT2
Barr, CE2
Torigoe, Y1
Wang, E1
Rowland, CR1
Goldfarb, SD3
Mannix, LK1
Adelman, JU1
Von, S1
Kozma, CM1
Lloyd, DK1
Pilgrim, AJ1
Simmons, VE1
de Jong, EG1

Reviews

3 reviews available for sumatriptan and Chest Pain

ArticleYear
Cardiovascular safety of 5HT1B/1D agonists--is there a cause for concern?
    Cephalalgia : an international journal of headache, 1998, Volume: 18, Issue:8

    Topics: Aged; Chest Pain; Contraindications; Coronary Circulation; Death, Sudden, Cardiac; Diagnosis, Differ

1998
ABC of the upper gastrointestinal tract. Oesophagus: Atypical chest pain and motility disorders.
    BMJ (Clinical research ed.), 2001, Oct-06, Volume: 323, Issue:7316

    Topics: Antacids; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Calci

2001
Almotriptan versus sumatriptan in migraine treatment: direct medical costs of managing adverse chest symptoms.
    The American journal of managed care, 2002, Volume: 8, Issue:3 Suppl

    Topics: Chest Pain; Drug Costs; Electrocardiography; Humans; Indoles; Migraine Disorders; Serotonin Receptor

2002

Trials

5 trials available for sumatriptan and Chest Pain

ArticleYear
Is chest pain after sumatriptan oesophageal in origin?
    Lancet (London, England), 1994, Oct-08, Volume: 344, Issue:8928

    Topics: Adult; Chest Pain; Cross-Over Studies; Double-Blind Method; Electrocardiography; Esophageal Motility

1994
Safety trial with the 5HT1B/1D agonist avitriptan (BMS-180048) in patients with migraine who have experienced pressure, tightness, and/or pain in the chest, neck, and/or throat following sumatriptan.
    Cephalalgia : an international journal of headache, 1998, Volume: 18, Issue:8

    Topics: Adult; Chest Pain; Diagnosis, Differential; Electrocardiography; Electrocardiography, Ambulatory; Fe

1998
Exercise testing in patients with chest pain to sumatriptan.
    The Netherlands journal of medicine, 1998, Volume: 53, Issue:6

    Topics: Adult; Angina Pectoris; Case-Control Studies; Chest Pain; Diagnosis, Differential; Electrocardiograp

1998
Almotriptan versus sumatriptan in migraine treatment: direct medical costs of managing adverse chest symptoms.
    The American journal of managed care, 2002, Volume: 8, Issue:3 Suppl

    Topics: Chest Pain; Drug Costs; Electrocardiography; Humans; Indoles; Migraine Disorders; Serotonin Receptor

2002
Coronary vasospasm and sumatriptan.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: Chest Pain; Coronary Vasospasm; Humans; Indoles; Sulfonamides; Sumatriptan; Vasoconstrictor Agents

1992

Other Studies

19 other studies available for sumatriptan and Chest Pain

ArticleYear
Sumatriptan-induced chest symptoms in Japanese.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:8

    Topics: Chest Pain; Humans; Japan; Migraine Disorders; Myocardial Ischemia; Serotonin Receptor Agonists; Sum

2002
Evidence against strong correlation between chest symptoms and ischemic coronary changes after subcutaneous sumatriptan injection.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:8

    Topics: Adolescent; Adult; Chest Pain; Female; Humans; Injections, Subcutaneous; Japan; Male; Middle Aged; M

2002
The comparative clinical and economic benefits of drugs should be established and discussed as part of any formulary decision process.
    The American journal of managed care, 2002, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Chest Pain; Child; Cost-Benefit Analysis; Female; Formularies as Topic; Humans; M

2002
Oral sumatriptan-induced myocardial infarction.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:3

    Topics: Cardiac Catheterization; Chest Pain; Electrocardiography; Enzymes; Female; Heart Function Tests; Hem

2004
Sumatriptan-induced chest pain.
    Lancet (London, England), 1994, Nov-26, Volume: 344, Issue:8935

    Topics: Chest Pain; Hemodynamics; Humans; Sumatriptan

1994
Adverse reactions attributed to sumatriptan. A postmarketing study in general practice.
    European journal of clinical pharmacology, 1994, Volume: 47, Issue:4

    Topics: Adult; Chest Pain; Female; Follow-Up Studies; Humans; Male; Myocardial Infarction; Product Surveilla

1994
Sumatriptan-induced chest pain.
    Lancet (London, England), 1994, Nov-26, Volume: 344, Issue:8935

    Topics: Chest Pain; Esophagus; Humans; Peristalsis; Receptors, Serotonin; Sumatriptan

1994
Sumatriptan-induced chest pain.
    Lancet (London, England), 1994, Dec-17, Volume: 344, Issue:8938

    Topics: Adult; Chest Pain; Female; Humans; Male; Middle Aged; Sumatriptan

1994
Sumatriptan and chest pain.
    Lancet (London, England), 1993, Jun-19, Volume: 341, Issue:8860

    Topics: Chest Pain; Electrocardiography; Hemodynamics; Humans; Indoles; Myocardial Infarction; Myocardial Is

1993
Sumatriptan and chest pain.
    Lancet (London, England), 1993, Sep-11, Volume: 342, Issue:8872

    Topics: Chest Pain; Electrocardiography; Humans; Indoles; Myocardial Infarction; Serotonin Receptor Agonists

1993
Postmarketing study of cardiovascular adverse reactions associated with sumatriptan.
    BMJ (Clinical research ed.), 1993, Nov-06, Volume: 307, Issue:6913

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Cardiovascular Diseases; Chest Pain; Female; Humans;

1993
Sumatriptan and panic-like symptoms.
    The American journal of psychiatry, 1996, Volume: 153, Issue:11

    Topics: Chest Pain; Cluster Headache; Humans; Migraine Disorders; Panic Disorder; Serotonin Receptor Agonist

1996
Chest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patients.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:8

    Topics: Adult; Angina Pectoris; Chest Pain; Female; Humans; Male; Middle Aged; Migraine Disorders; Retrospec

1996
Characteristics and determinants of sumatriptan-associated chest pain.
    Archives of neurology, 1997, Volume: 54, Issue:11

    Topics: Adult; Age Distribution; Chest Pain; Cohort Studies; Female; Humans; Hypertension; Male; Middle Aged

1997
Human isolated coronary artery contraction to sumatriptan: a post hoc analysis.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:7

    Topics: Adult; Aged; Cause of Death; Chest Pain; Contraindications; Coronary Disease; Coronary Vessels; Dise

1999
Cost savings in migraine associated with less chest pain on new triptan therapy.
    The American journal of managed care, 2002, Volume: 8, Issue:3 Suppl

    Topics: Chest Pain; Cohort Studies; Cost Savings; Cost-Benefit Analysis; Data Collection; Female; Humans; In

2002
Impact of chest pain on cost of migraine treatment with almotriptan and sumatriptan.
    Headache, 2002, Volume: 42 Suppl 1

    Topics: Adolescent; Adult; Chest Pain; Cohort Studies; Cost Savings; Cost-Benefit Analysis; Drug Costs; Elec

2002
[Chest pain due to sumatriptan].
    Nederlands tijdschrift voor geneeskunde, 1992, Sep-05, Volume: 136, Issue:36

    Topics: Adult; Chest Pain; Electrocardiography; Female; Humans; Indoles; Male; Middle Aged; Serotonin Recept

1992
[Chest pain caused by sumatriptan].
    Nederlands tijdschrift voor geneeskunde, 1992, Oct-24, Volume: 136, Issue:43

    Topics: Angina Pectoris; Chest Pain; Humans; Indoles; Sulfonamides; Sumatriptan; Vasoconstrictor Agents

1992