sumatriptan has been researched along with Central Nervous System Diseases in 3 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Potential explanations for differences among triptans in the incidence of CNS side-effects may relate to pharmacological and pharmacokinetic differences, including receptor binding, lipophilicity, and the presence of active metabolites." | 2.42 | Triptans and CNS side-effects: pharmacokinetic and metabolic mechanisms. ( Dodick, DW; Martin, V, 2004) |
| "About every second (53%) migraineur using subcutaneous sumatriptan reports headache recurrence." | 2.39 | Clinical experiences from Sweden on the use of subcutaneously administered sumatriptan in migraine and cluster headache. ( Dahlöf, C; Ekbom, K; Persson, L, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dodick, DW | 1 |
| Martin, V | 1 |
| Pascual, J | 1 |
| Muñoz, P | 1 |
| Dahlöf, C | 1 |
| Ekbom, K | 1 |
| Persson, L | 1 |
2 reviews available for sumatriptan and Central Nervous System Diseases
| Article | Year |
|---|---|
Triptans and CNS side-effects: pharmacokinetic and metabolic mechanisms.
Topics: Animals; Central Nervous System Diseases; Humans; Migraine Disorders; Serotonin Receptor Agonists; S | 2004 |
Clinical experiences from Sweden on the use of subcutaneously administered sumatriptan in migraine and cluster headache.
Topics: Cardiovascular Diseases; Central Nervous System Diseases; Cluster Headache; Humans; Injections, Subc | 1994 |
1 other study available for sumatriptan and Central Nervous System Diseases
| Article | Year |
|---|---|
Correlation between lipophilicity and triptan outcomes.
Topics: Central Nervous System Diseases; Chemical Phenomena; Chemistry, Physical; Humans; Indoles; Migraine | 2005 |