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sumatriptan and Cardiovascular Stroke

sumatriptan has been researched along with Cardiovascular Stroke in 29 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Research Excerpts

ExcerptRelevanceReference
"The aim of this review is to describe: the mechanisms of action of triptans; the case-reports of acute myocardial infarction (AMI) associated with sumatriptan use; and the results of studies evaluating its tolerability and safety."8.86Sumatriptan therapy for headache and acute myocardial infarction. ( Ames, PR; Barra, S; Gaeta, G; Lanero, S; Madrid, A; Materazzi, C; Vitagliano, G, 2010)
"We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases."7.75Acute myocardial infarction with sumatriptan: a case report and review of the literature. ( Chalaupka, FD, 2009)
"Patients without cardiac risk factors may experience myocardial infarction following an oral dose of sumatriptan."7.72Oral sumatriptan-induced myocardial infarction. ( Hack, JB, 2004)
"Acute myocardial infarction occurred in a 43 year-old premenopausal woman with controlled hypertension and no known coronary artery disease following the use of the antimigraine medications sumatriptan succinate injectable form and methysergide maleate."7.70The association of the combination of sumatriptan and methysergide in myocardial infarction in a premenopausal woman. ( Bennett, L; Liston, H; Nappi, J; Usher, B, 1999)
"A 43-year-old healthy man developed transmural myocardial infarction shortly after ingesting sumatriptan succinate 100 mg for migraine."7.69Oral sumatriptan-associated transmural myocardial infarction. ( Gladstone, P; O'Connor, P, 1995)
"A total of 137 patients with chest pain associated with intake of sumatriptan were identified and compared with 229 consumers of sumatriptan without this adverse reaction."7.69Characteristics and determinants of sumatriptan-associated chest pain. ( Grobbee, DE; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1997)
"The pain of cluster headache attacks is severe, excruciating and selectively responsive to subcutaneous sumatriptan."5.33Acute myocardial infarction after sumatriptan administration for cluster headache. ( Anghileri, E; Perini, F; Toso, V, 2006)
"The aim of this review is to describe: the mechanisms of action of triptans; the case-reports of acute myocardial infarction (AMI) associated with sumatriptan use; and the results of studies evaluating its tolerability and safety."4.86Sumatriptan therapy for headache and acute myocardial infarction. ( Ames, PR; Barra, S; Gaeta, G; Lanero, S; Madrid, A; Materazzi, C; Vitagliano, G, 2010)
"We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases."3.75Acute myocardial infarction with sumatriptan: a case report and review of the literature. ( Chalaupka, FD, 2009)
"Patients without cardiac risk factors may experience myocardial infarction following an oral dose of sumatriptan."3.72Oral sumatriptan-induced myocardial infarction. ( Hack, JB, 2004)
"Acute myocardial infarction occurred in a 43 year-old premenopausal woman with controlled hypertension and no known coronary artery disease following the use of the antimigraine medications sumatriptan succinate injectable form and methysergide maleate."3.70The association of the combination of sumatriptan and methysergide in myocardial infarction in a premenopausal woman. ( Bennett, L; Liston, H; Nappi, J; Usher, B, 1999)
"A 43-year-old healthy man developed transmural myocardial infarction shortly after ingesting sumatriptan succinate 100 mg for migraine."3.69Oral sumatriptan-associated transmural myocardial infarction. ( Gladstone, P; O'Connor, P, 1995)
"A total of 137 patients with chest pain associated with intake of sumatriptan were identified and compared with 229 consumers of sumatriptan without this adverse reaction."3.69Characteristics and determinants of sumatriptan-associated chest pain. ( Grobbee, DE; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1997)
"Triptans, 5-HT1B/1D agonists used in migraine treatment, are rarely involved in serious coronary events due to vasospasm."2.41[Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause]. ( Hedenmalm, K, 2000)
"The pain of cluster headache attacks is severe, excruciating and selectively responsive to subcutaneous sumatriptan."1.33Acute myocardial infarction after sumatriptan administration for cluster headache. ( Anghileri, E; Perini, F; Toso, V, 2006)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (55.17)18.2507
2000's11 (37.93)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jensen, C1
Riddle, M1
Dodick, DW1
Chalaupka, FD1
Barra, S1
Lanero, S1
Madrid, A1
Materazzi, C1
Vitagliano, G1
Ames, PR1
Gaeta, G1
Solomon, S1
Petro, DJ1
Hack, JB1
Tornøe, K1
Steffensen, R1
Anghileri, E1
Toso, V1
Perini, F1
Al Ali, AM1
Straatman, LP1
Allard, MF1
Ignaszewski, AP1
Weir, RA1
Oldroyd, KG1
Walters, MR1
Ottervanger, JP6
van Witsen, TB1
Valkenburg, HA2
Grobbee, DE2
Stricker, BH6
Schoenen, J1
Delrée, P1
Moonen, G1
Paalman, HJ1
Boxma, GL1
Lloyd, DK1
Simmons, V1
Chester, AH1
O'Neil, GS1
Yacoub, MH1
Hillis, WS2
MacIntyre, PD2
Mueller, L1
Gallagher, RM1
Ciervo, CA1
O'Connor, P1
Gladstone, P1
Abbrescia, VD1
Pearlstein, L1
Kotler, M1
Wilson, JH1
Main, ML1
Ramaswamy, K1
Andrews, TC1
Liston, H1
Bennett, L1
Usher, B1
Nappi, J1
Hedenmalm, K1

Reviews

4 reviews available for sumatriptan and Cardiovascular Stroke

ArticleYear
Sumatriptan therapy for headache and acute myocardial infarction.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:16

    Topics: Adolescent; Adult; Animals; Coronary Vasospasm; Female; Humans; Male; Middle Aged; Migraine Disorder

2010
Eosinophilic myocarditis: case series and review of literature.
    The Canadian journal of cardiology, 2006, Volume: 22, Issue:14

    Topics: Adrenergic beta-Antagonists; Adult; Angina, Unstable; Angiotensin-Converting Enzyme Inhibitors; Eosi

2006
Drug-induced chest pain and myocardial infarction. Reports to a national centre and review of the literature.
    European journal of clinical pharmacology, 1997, Volume: 53, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Angina Pectoris; Calcium Channel Blockers; Female; Humans;

1997
[Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause].
    Lakartidningen, 2000, Jun-21, Volume: 97, Issue:25

    Topics: Contraindications; Coronary Disease; Humans; Migraine Disorders; Myocardial Infarction; Risk Assessm

2000

Other Studies

25 other studies available for sumatriptan and Cardiovascular Stroke

ArticleYear
ST-Elevation Myocardial Infarction After Sumitriptan Ingestion in Patient with Normal Coronary Arteries.
    The western journal of emergency medicine, 2015, Volume: 16, Issue:5

    Topics: Electrocardiography; Emergency Service, Hospital; Female; Humans; Middle Aged; Migraine Disorders; M

2015
CASE 1: the well-intentioned triptan prescriber.
    Headache, 2008, Volume: 48, Issue:6

    Topics: Cluster Headache; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Malpractice; Middle

2008
Acute myocardial infarction with sumatriptan: a case report and review of the literature.
    Headache, 2009, Volume: 49, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aspirin; Coronary Vasospasm; Coronary Vessels; Echocardi

2009
The hazards of medication refills by telephone.
    Headache, 2002, Volume: 42, Issue:8

    Topics: Drug Prescriptions; Female; Humans; Middle Aged; Migraine Disorders; Myocardial Infarction; Serotoni

2002
Cerebral vasoconstriction and stroke after use of serotonergic drugs.
    Neurology, 2002, Aug-27, Volume: 59, Issue:4

    Topics: Antidepressive Agents; Brain; Cerebrovascular Circulation; Dietary Supplements; Drug and Narcotic Co

2002
[Use of triptanes according to indications. Risk of infarct is not increased].
    MMW Fortschritte der Medizin, 2004, Feb-12, Volume: 146, Issue:7

    Topics: Cerebral Infarction; Clinical Trials as Topic; Coronary Circulation; Humans; Indoles; Injections, In

2004
Oral sumatriptan-induced myocardial infarction.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:3

    Topics: Cardiac Catheterization; Chest Pain; Electrocardiography; Enzymes; Female; Heart Function Tests; Hem

2004
[ST-segment elevation myocardial infarction following treatment with sumatriptan].
    Ugeskrift for laeger, 2005, Jan-03, Volume: 167, Issue:1

    Topics: Adult; Electrocardiography; Female; Humans; Myocardial Infarction; Sumatriptan; Vasoconstrictor Agen

2005
Acute myocardial infarction after sumatriptan administration for cluster headache.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2006, Volume: 26, Issue:6

    Topics: Adult; Cluster Headache; Humans; Male; Myocardial Infarction; Sumatriptan; Vasoconstrictor Agents

2006
Myocardial infarction after oral sumatriptan use in a woman with normal coronary arteries.
    The American journal of medicine, 2007, Volume: 120, Issue:11

    Topics: Coronary Vessels; Female; Humans; Middle Aged; Myocardial Infarction; Sumatriptan; Vasoconstrictor A

2007
Adverse reactions attributed to sumatriptan. A postmarketing study in general practice.
    European journal of clinical pharmacology, 1994, Volume: 47, Issue:4

    Topics: Adult; Chest Pain; Female; Follow-Up Studies; Humans; Male; Myocardial Infarction; Product Surveilla

1994
Acute myocardial infarction in a young female migraineur: sumatriptan suspected, but found not guilty.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:4

    Topics: Acute Disease; Adult; Female; Humans; Migraine Disorders; Myocardial Infarction; Sumatriptan

1994
Transmural myocardial infarction with sumatriptan.
    Lancet (London, England), 1993, Apr-03, Volume: 341, Issue:8849

    Topics: Cluster Headache; Electrocardiography; Exercise Test; Female; Heparin; Humans; Indoles; Injections,

1993
Adverse reactions associated with sumatriptan.
    Lancet (London, England), 1993, Apr-24, Volume: 341, Issue:8852

    Topics: Contraindications; Coronary Disease; Humans; Indoles; Myocardial Infarction; Serotonin Receptor Agon

1993
Sumatriptan and ischaemic heart disease.
    Lancet (London, England), 1993, May-29, Volume: 341, Issue:8857

    Topics: Adult; Coronary Vessels; Humans; In Vitro Techniques; Indoles; Middle Aged; Myocardial Infarction; P

1993
Sumatriptan and chest pain.
    Lancet (London, England), 1993, Jun-19, Volume: 341, Issue:8860

    Topics: Chest Pain; Electrocardiography; Hemodynamics; Humans; Indoles; Myocardial Infarction; Myocardial Is

1993
Sumatriptan and chest pain.
    Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864

    Topics: Coronary Circulation; Ergot Alkaloids; Humans; Indoles; Myocardial Infarction; Serotonin; Serotonin

1993
Sumatriptan and chest pain.
    Lancet (London, England), 1993, Sep-11, Volume: 342, Issue:8872

    Topics: Chest Pain; Electrocardiography; Humans; Indoles; Myocardial Infarction; Serotonin Receptor Agonists

1993
[Heart infarct following administration of sumatriptan (Imigran)].
    Nederlands tijdschrift voor geneeskunde, 1993, Jan-16, Volume: 137, Issue:3

    Topics: Female; Humans; Indoles; Middle Aged; Myocardial Infarction; Sulfonamides; Sumatriptan; Vasoconstric

1993
Vasospasm-induced myocardial infarction with sumatriptan.
    Headache, 1996, Volume: 36, Issue:5

    Topics: Coronary Vasospasm; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Migraine Disorders;

1996
Oral sumatriptan-associated transmural myocardial infarction.
    Neurology, 1995, Volume: 45, Issue:12

    Topics: Administration, Oral; Adult; Coronary Angiography; Electrocardiography; Humans; Male; Myocardial Inf

1995
Sumatriptan-associated myocardial infarction: report of case with attention to potential risk factors.
    The Journal of the American Osteopathic Association, 1997, Volume: 97, Issue:3

    Topics: Female; Humans; Middle Aged; Migraine Disorders; Myocardial Infarction; Risk Factors; Serotonin Rece

1997
Characteristics and determinants of sumatriptan-associated chest pain.
    Archives of neurology, 1997, Volume: 54, Issue:11

    Topics: Adult; Age Distribution; Chest Pain; Cohort Studies; Female; Humans; Hypertension; Male; Middle Aged

1997
Cardiac arrest and myocardial infarction immediately after sumatriptan injection.
    Annals of internal medicine, 1998, May-15, Volume: 128, Issue:10

    Topics: Female; Heart Arrest; Humans; Injections, Subcutaneous; Middle Aged; Myocardial Infarction; Serotoni

1998
The association of the combination of sumatriptan and methysergide in myocardial infarction in a premenopausal woman.
    Archives of internal medicine, 1999, Mar-08, Volume: 159, Issue:5

    Topics: Adult; Female; Humans; Methysergide; Myocardial Infarction; Premenopause; Serotonin Antagonists; Ser

1999