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sumatriptan and Cardiovascular Diseases

sumatriptan has been researched along with Cardiovascular Diseases in 11 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
" In AT1, which was previously published in part, group differences in adverse events (AEs) were analyzed using the Fisher exact test, and response rates were compared using logistic regression."2.46Safety and tolerability of frovatriptan in the acute treatment of migraine and prevention of menstrual migraine: Results of a new analysis of data from five previously published studies. ( Campbell, JC; Hu, X; MacGregor, EA; Pawsey, SP, 2010)
"Sumatriptan has been instrumental in defining a biological basis for migraine."2.43Sumatriptan: update and review. ( Cady, R; Schreiber, C, 2006)
"About every second (53%) migraineur using subcutaneous sumatriptan reports headache recurrence."2.39Clinical experiences from Sweden on the use of subcutaneously administered sumatriptan in migraine and cluster headache. ( Dahlöf, C; Ekbom, K; Persson, L, 1994)
"Triptans are widely used to treat migraine but have been associated with stroke, myocardial infarction (MI), and ischemic heart disease (IHD) in case reports."1.32Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice. ( Brown, MM; Hall, GC; MacRae, KD; Mo, J, 2004)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (45.45)18.2507
2000's5 (45.45)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MacGregor, EA1
Pawsey, SP1
Campbell, JC1
Hu, X1
Adelman, JU1
Lewit, EJ1
Hall, GC1
Brown, MM1
Mo, J1
MacRae, KD1
Dodick, DW1
Papademetriou, V1
Cady, R1
Schreiber, C1
Dahlöf, C1
Ekbom, K1
Persson, L1
Gaist, D1
Grundemar, L1
Ottervanger, JP1
van Witsen, TB1
Valkenburg, HA1
Stricker, BH1
O'Quinn, S1
Davis, RL1
Gutterman, DL1
Pait, GD1
Fox, AW1
Welch, KM1
Mathew, NT1
Stone, P1
Rosamond, W1
Saiers, J1
Gutterman, D1

Reviews

6 reviews available for sumatriptan and Cardiovascular Diseases

ArticleYear
Safety and tolerability of frovatriptan in the acute treatment of migraine and prevention of menstrual migraine: Results of a new analysis of data from five previously published studies.
    Gender medicine, 2010, Volume: 7, Issue:2

    Topics: Acute Disease; Carbazoles; Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Dose-Respon

2010
Comparative aspects of triptans in treating migraine.
    Clinical cornerstone, 2001, Volume: 4, Issue:3

    Topics: Carbazoles; Cardiovascular Diseases; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Sa

2001
Sumatriptan: update and review.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:11

    Topics: Animals; Cardiovascular Diseases; Drug Interactions; Drug Tolerance; Humans; Naproxen; Sumatriptan;

2006
Clinical experiences from Sweden on the use of subcutaneously administered sumatriptan in migraine and cluster headache.
    Archives of neurology, 1994, Volume: 51, Issue:12

    Topics: Cardiovascular Diseases; Central Nervous System Diseases; Cluster Headache; Humans; Injections, Subc

1994
[Sumatriptan and cardiac complaints. Careful cardiac anamnesis is needed prior to treatment].
    Lakartidningen, 1994, Apr-27, Volume: 91, Issue:17

    Topics: Cardiovascular Diseases; Coronary Disease; Humans; Migraine Disorders; Sumatriptan

1994
Tolerability of sumatriptan: clinical trials and post-marketing experience.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:8

    Topics: Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Migraine Disor

2000

Trials

1 trial available for sumatriptan and Cardiovascular Diseases

ArticleYear
Prospective large-scale study of the tolerability of subcutaneous sumatriptan injection for acute treatment of migraine.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Cardiovascular Diseases; Cerebrovascul

1999

Other Studies

4 other studies available for sumatriptan and Cardiovascular Diseases

ArticleYear
Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice.
    Neurology, 2004, Feb-24, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Cardiovascular Diseases; Cause

2004
Cardiovascular safety of triptans.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:7

    Topics: Cardiovascular Diseases; Humans; Indoles; Pyrrolidines; Sumatriptan; Tryptamines

2004
[Sumatriptan (Imigran) and cardiovascular side effects].
    Ugeskrift for laeger, 1994, May-16, Volume: 156, Issue:20

    Topics: Adult; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Risk Factors; Sumatriptan

1994
Postmarketing study of cardiovascular adverse reactions associated with sumatriptan.
    BMJ (Clinical research ed.), 1993, Nov-06, Volume: 307, Issue:6913

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Cardiovascular Diseases; Chest Pain; Female; Humans;

1993