sumatriptan and Atypical Cluster Headache studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Research Excerpts

Excerpt	Relevance	Reference
"The efficacy, safety, and tolerability of subcutaneous sumatriptan in the acute treatment of cluster headache were investigated in a multicenter study over a period of up to 1 year."	9.08	Acute therapy for cluster headache with sumatriptan: findings of a one-year long-term study. ( Deuschl, G; Göbel, H; Heinze, A; Lindner, V; Ribbat, M, 1998)
"To document the relationship between the 5-HT receptor agonist sumatriptan and a change in the nature of cluster headache in four cases."	7.70	Alteration in nature of cluster headache during subcutaneous administration of sumatriptan. ( Hering-Hanit, R, 2000)
"The pain of cluster headache attacks is severe, excruciating and selectively responsive to subcutaneous sumatriptan."	5.33	Acute myocardial infarction after sumatriptan administration for cluster headache. ( Anghileri, E; Perini, F; Toso, V, 2006)
"The efficacy, safety, and tolerability of subcutaneous sumatriptan in the acute treatment of cluster headache were investigated in a multicenter study over a period of up to 1 year."	5.08	Acute therapy for cluster headache with sumatriptan: findings of a one-year long-term study. ( Deuschl, G; Göbel, H; Heinze, A; Lindner, V; Ribbat, M, 1998)
" Attack treatment in cluster headache is based on sumatriptan and oxygen."	4.82	[Treatment of cluster headache]. ( Fabre, N, 2005)
"To assess the reimbursement options and accessibility of three effective medicines for cluster headache (CH) (subcutaneous sumatriptan, oxygen, and zolmitriptan spray) across the European Union (EU)."	3.96	Availability of Effective Evidence-Based Symptomatic Treatments for Cluster Headache in the EU Countries-A Survey of the European Headache Alliance and European Headache Federation. ( De La Torre, ER; Di Lorenzo, C; Mitsikostas, D; Palmaro, A; Rossi, P, 2020)
"Subjects with persistent interictal pain were more likely to have chronic cluster, allodynia, and suboptimal response to sumatriptan, suggesting that interictal pain in cluster headache may predict a more severe disease process."	3.76	Interictal pain in cluster headache. ( Marmura, MJ; Pello, SJ; Young, WB, 2010)
"To document the relationship between the 5-HT receptor agonist sumatriptan and a change in the nature of cluster headache in four cases."	3.70	Alteration in nature of cluster headache during subcutaneous administration of sumatriptan. ( Hering-Hanit, R, 2000)
"For the acute treatment of cluster headache attacks, there is a strong recommendation for oxygen (100%) with a flow of at least 12 L/min over 15 min and 6 mg subcutaneous sumatriptan."	3.01	European Academy of Neurology guidelines on the treatment of cluster headache. ( Aleksovska, K; Carvalho, V; Evers, S; Goadsby, PJ; Jensen, RH; Leone, M; Manzoni, GC; May, A; Pascual, J; Pozo-Rosich, P; Romoli, M, 2023)
"The management of cluster headache is similar to that of other primary headache disorders and can be broadly divided into acute and preventive treatments."	3.01	Management of cluster headache: Treatments and their mechanisms. ( Burish, MJ; Peng, KP, 2023)
"Sumatriptan injectable was also effective for headache relief and was found to be better than nasal spray zolmitriptan (OR 2."	2.82	Network meta-analysis of therapies for cluster headache: Effects of acute therapies for episodic and chronic cluster. ( Christie, S; Hutton, B; Medrea, I; Tepper, SJ; Thavorn, K, 2022)
"What this paper adds Cluster headache in children and adolescents is poorly studied."	2.72	Cluster headache in children and adolescents: a systematic review of case reports. ( Barbosa, BLF; Bastos, SNMAN; Jevoux, C; Krymchantowski, A; Krymchantowski, AG; Silva, SF; Silva-Néto, RP, 2021)
"We enrolled 81 consecutive patients with cluster headache and recorded their use of SQ sumatriptan and oxygen."	2.71	Treatment of cluster headache attacks with less than 6 mg subcutaneous sumatriptan. ( Akova-Oztürk, E; Evers, S; Gregor, N; Husstedt, IW; Kraemer, C; Schlesiger, C, 2005)
"Sumatriptan was also superior to placebo considering initial response, meaningful relief, and relief of associated symptoms."	2.71	Intranasal sumatriptan in cluster headache: randomized placebo-controlled double-blind study. ( Aurora, SK; Bahra, A; Ferrari, MD; Goadsby, PJ; Martin, V; Mathew, NT; Ramadan, N; van Vliet, JA, 2003)
"Sumatriptan nasal spray was applied in 154 "moderate" to "very severe" cluster headache attacks."	2.70	Treatment of acute cluster headache with 20 mg sumatriptan nasal spray--an open pilot study. ( Arnold, G; Einhäupl, KM; Kinze, S; Reuter, U; Schuh-Hofer, S, 2002)
"Sumatriptan is an effective and well-tolerated treatment for acute attacks of cluster headache."	2.67	Treatment of acute cluster headache with sumatriptan. ( , 1991)
"Cluster headache is characterized by severe, unilateral headache attacks of orbital, supraorbital or temporal pain lasting 15-180 min accompanied by ipsilateral lacrimation, rhinorrhea and other cranial autonomic manifestations."	2.55	Cluster headache: present and future therapy. ( Cecchini, AP; Giustiniani, A; Leone, M, 2017)
"The TACs include cluster headache, paroxysmal hemicrania, and short-lasting neuralgiform headache attacks with conjunctival injection and tearing; hemicrania continua, although classified separately by the International Headache Society, shares many features of both migraine and the TACs."	2.49	Primary headache disorders. ( Benoliel, R; Eliav, E, 2013)
"For preventive treatment of cluster headache, calcium channel blocker (verapamil) and steroids are recommended."	2.49	[New treatments for cluster headache]. ( Shimizu, T, 2013)
"Cluster headache is an uncommon,severely painful, and disabling condition, with rapid onset."	2.49	Triptans for acute cluster headache. ( Derry, S; Law, S; Moore, RA, 2013)
"Cluster headache is a rare primary neurovascular headache and a severe pain condition with unilateral headache over 15-180 minutes and concomitant unilateral autonomic symptoms."	2.48	Oral triptans in the preventive management of cluster headache. ( Limmroth, V; Pageler, L, 2012)
" Pharmacologically, pharmacokinetic parameters, in particular bioavailability, T(max) and C(max) are responsible for the wide efficacy of the compound and the limited adverse effect (AE) profile."	2.48	Sumatriptan succinate : pharmacokinetics of different formulations in clinical practice. ( Casolla, B; Lionetto, L; Martelletti, P; Negro, A; Simmaco, M, 2012)
"In patients whose migraine attacks have historically failed to respond to oral triptans, this route of administration has also proven to be more consistent and effective."	2.47	Sumatriptan needle-free subcutaneous (Sumavel(®) DosePro™) approved for the acute treatment of migraine, with or without aura, and cluster headaches. ( Freitag, FG, 2011)
"Zolmitriptan was administered either orally or intranasally, and sumatriptan either subcutaneously or intranasally."	2.46	Triptans for acute cluster headache. ( Derry, S; Law, S; Moore, RA, 2010)
"TACs include cluster headache (CH), paroxysmal hemicrania (PH) and short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT syndrome)."	2.44	[Pathophysiology and treatment of trigeminal autonomic cephalalgias]. ( Cohen, AS; Goadsby, PJ, 2008)
"The group includes cluster headache (CH), paroxysmal hemicrania (PH), and short-lasting neuralgiform headache with conjunctival injection and tearing (SUNCT)."	2.44	[Trigeminal autonomic cephalgias: diagnostic and therapeutic implications]. ( Rosenberg-Nordmann, M; Sprenger, T; Tölle, TR, 2007)
"For the acute treatment of cluster headache attacks, oxygen (100%) with a flow of at least 7 l/min over 15 min and 6 mg subcutaneous sumatriptan are drugs of first choice."	2.43	EFNS guidelines on the treatment of cluster headache and other trigeminal-autonomic cephalalgias. ( Afra, J; Evers, S; Goadsby, PJ; Leone, M; Linde, M; May, A; Sándor, PS, 2006)
"The pain produced during a cluster headache is more severe than that generated by any other primary headache."	2.43	Cluster headache: diagnosis and treatment. ( Rozen, TD, 2005)
" Also, some nasal preparations have significant adverse effects or are not well absorbed and therefore do not work consistently; others are more challenging to administer as a result of their delivery apparatus."	2.42	Intranasal medications for the treatment of migraine and cluster headache. ( Bigal, ME; Rapoport, AM; Sheftell, FD; Tepper, SJ, 2004)
"Cluster headache is the most severe headache syndrome known to humans."	2.41	New treatments in cluster headache. ( Rozen, TD, 2002)
"Zolmitriptan is a potent 5-HT(1B/1D) agonist whose targets include the peripheral and central components of the trigeminovascular system."	2.41	Zolmitriptan: differences from sumatriptan. ( Boes, CJ; Goadsby, PJ, 2001)
"All papers on cluster headaches were reviewed according to preset criteria under the following headings: classification, epidemiology, aetiology, pathophysiology, and clinical features."	2.41	Cluster headache: review of the literature. ( Zakrzewska, JM, 2001)
"Management of cluster headache has greatly changed in recent years although most of the drugs used have not received approval for this indications."	2.41	[Treatment of cluster headache]. ( Fabre, N, 2000)
"Recurrence of migraine, long-term usage, and side effects of serotonin1D agonists are included in the review."	2.40	Serotonin 1D (5-HT1D) agonists and other agents in acute migraine. ( Mathew, NT, 1997)
"Headaches are a common entity in the ambulatory population."	2.40	Diagnosis, prophylaxis, and treatment of headaches in the athlete. ( Kaplan, B; Swain, RA, 1997)
"Atypical forms of cluster headache (CH) are characterized by the association of CH to other headaches and facial neuralgias."	2.40	[Unusual varieties of cluster headache]. ( Alberca, R, 1997)
"Sumatriptan is a selective agonist at serotonin 5-HT1-like receptors, including 5-HT1B/1D subtypes."	2.40	Sumatriptan. An updated review of its use in migraine. ( Markham, A; Perry, CM, 1998)
"Sumatriptan is a potent and selective agonist at a vascular serotonin1 (5-hydroxytryptamine1; 5-HT1) receptor subtype (similar to 5-HT1D) and is used in acute treatment of migraine and cluster headache."	2.39	Sumatriptan. A reappraisal of its pharmacology and therapeutic efficacy in the acute treatment of migraine and cluster headache. ( McTavish, D; Plosker, GL, 1994)
"About every second (53%) migraineur using subcutaneous sumatriptan reports headache recurrence."	2.39	Clinical experiences from Sweden on the use of subcutaneously administered sumatriptan in migraine and cluster headache. ( Dahlöf, C; Ekbom, K; Persson, L, 1994)
"Sumatriptan is a potent and selective agonist at the vascular 5HT1 receptor which mediates constriction of certain large cranial blood vessels and/or inhibits the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater following activation of the trigeminovascular system."	2.39	Migraine and cluster headache--their management with sumatriptan: a critical review of the current clinical experience. ( Diener, HC; Pfaffenrath, V; Schoenen, J; Steiner, TJ; Wilkinson, M, 1995)
"The spontaneous capricious course of cluster headache may give rise to some problems when treatment is being evaluated."	2.39	Treatment of cluster headache: clinical trials, design and results. ( Ekbom, K, 1995)
"Sumatriptan is a novel, highly effective drug against migraine and cluster headache attacks."	2.38	Clinical effects and mechanism of action of sumatriptan in migraine. ( Ferrari, MD; Saxena, PR, 1992)
"Sumatriptan has a rapid onset of action and a large volume of distribution."	2.38	Sumatriptan: a new drug for vascular headache. ( Hsu, VD, 1992)
"Sumatriptan is an agonist of 5-HT1 -like receptors and exerts a selective vasoconstricting effect on the arteries of the head, particularly in the rami of the carotid artery."	2.38	[Sumatriptan and its use in treatment of migraine and cluster headaches]. ( Prusiński, A, 1992)
"Sumatriptan is a highly selective 5 HT1 receptor subtype agonist."	2.38	[Sumatriptan--future development, alternative features and potential new indications]. ( Arnold, WS, 1992)
"Sumatriptan is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache."	2.38	Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. ( Clissold, SP; Dechant, KL, 1992)
" Cluster headache is not optimally treated and few clinical trials are available to model therapy, especially dosing and administration."	1.72	Cluster Headache: Opportunities for Pharmacists to Improve Care. ( Clark, AS; Smith, TR; Wenzel, R, 2022)
"Data from 8369 cluster headache attacks, containing information about acute medication taken and the assessment of its effect, were collected from 133 participants using an online platform and a smartphone app."	1.62	Effectiveness of medication in cluster headache. ( Amann, TK; Drescher, J; Gaul, C; Khouri, A; Kropp, P; Scheidt, J; Siebenhaar, Y, 2021)
"Episodic cluster headache is more responsive to acute therapy than chronic."	1.62	Real-life treatment of cluster headache in a tertiary headache center - results from the Danish Cluster Headache Survey. ( Barloese, M; Jensen, RH; Lund, N; Petersen, AS, 2021)
"The patient was diagnosed with chronic cluster headache (CCH) according to the third edition of the International Classification of Headache Disorders."	1.56	Chronic Cluster Headache with a Pediatric Onset: The First Japanese Case Report. ( Danno, D; Kashiwaya, Y; Kikui, S; Sugiyama, H; Takeshima, T, 2020)
"Cluster headache is classified as a primary headache by definition not caused by an underlying pathology."	1.43	Chronic cluster headache and the pituitary gland. ( De Pue, A; Lutin, B; Paemeleire, K, 2016)
"The therapeutic procedures of cluster headache begin from the precise diagnose."	1.39	[Therapeuetic aspects of cluster headache in the practical clinical site]. ( Owada, K, 2013)
"Verapamil 360 mg/day was found to be superior to placebo in one clinical trial."	1.38	Management of cluster headache. ( Jensen, RH; Tfelt-Hansen, PC, 2012)
"In about 20% of chronic cluster headache (CH) cases, drugs may become ineffective."	1.35	Costs of hypothalamic stimulation in chronic drug-resistant cluster headache: preliminary data. ( Broggi, G; Bussone, G; Cecchini, AP; Franzini, A; Leone, M; Mea, E, 2009)
"Cluster headache is a condition of extremely intense unilateral pain in the ocular or temporal region."	1.35	[Cluster headache]. ( Nissilä, M, 2009)
"A young woman had typical cluster headache attacks and a pituitary mass lesion."	1.34	Typical cluster headache caused by granulomatous pituitary involvement. ( Favier, I; Ferrari, MD; Haan, J; van Duinen, SG, 2007)
"The pain of cluster headache attacks is severe, excruciating and selectively responsive to subcutaneous sumatriptan."	1.33	Acute myocardial infarction after sumatriptan administration for cluster headache. ( Anghileri, E; Perini, F; Toso, V, 2006)
"Symptomatic cluster headache related to ocular pathologies have been rarely described."	1.33	Cluster-like headache after surgical crystalline removal and intraocular lens implant: a case report. ( Dainese, F; Lisotto, C; Maggioni, F; Mainardi, F; Zanchin, G, 2005)
"Sumatriptan nasal spray were constantly effective in both early stage and late stage of cluster periods."	1.33	[Sumatriptan nasal spray for the treatment of cluster headache]. ( Oda, A; Watanabe, M, 2005)
"The clinical management of cluster headache (CH) attacks requires a symptomatic treatment that is rapidly effective in resolving or significantly reducing symptoms."	1.32	Cluster headache: symptomatic treatment. ( Manzoni, GC; Torelli, P, 2004)
"Episodic cluster headache (ECH) was recorded in 79% while 21% had chronic cluster headache (CCH)."	1.32	Diagnostic delays and mis-management in cluster headache. ( Bahra, A; Goadsby, PJ, 2004)
"The sumatriptan-induced increase of growth hormone concentrations was significantly (P < 0."	1.32	Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with sumatriptan. ( Arvat, E; Del Rizzo, P; Ferrero, M; Gianotti, L; Limone, P; Lo Giudice, R; Pinessi, L; Rainero, I; Rivoiro, C; Valfrè, W, 2003)
"All patients hospitalised for cluster headache (n = 37) at the Department of Neurology, Haukeland University Hospital 1988-1998 were studied."	1.31	[Patients with cluster headache in a neurological department]. ( Flote, VG; Gilhus, NE, 2000)
"A 60-year-old woman with secondary chronic cluster headache had increased serum ferritin and serum transferrin saturation and was homozygous for the C282Y mutation in the HFE gene, which is indicative of hereditary haemochromatosis."	1.31	Hereditary haemochromatosis in two cousins with cluster headache. ( Bjerve, KS; Hagen, K; Stovner, LJ; Waage, A, 2002)
" However, knowledge of the long-term use of sumatriptan in unselected patients was lacking."	1.30	Use and overuse of sumatriptan. Pharmacoepidemiological studies based on prescription register and interview data. ( Gaist, D, 1999)
"Many cluster headache patients had not, to their knowledge, been prescribed or used the best symptomatic and prophylactic treatments for cluster headache."	1.30	Episodic cluster headache in a community: clinical features and treatment. ( Becker, WJ; Riess, CM; Robertson, M, 1998)
"Cluster headache is a rare but very typical disease."	1.30	[Cluster headache: misjudged because unknown]. ( Koudstaal, PJ; Ridderikhoff, J, 1997)
"Treatment with sumatriptan was effective in 88% of the attacks and 57% of the patients were pain-free within 15 min after injection; 42% of the patients became painfree within 15 min after at least 90% of their attacks."	1.30	[Acute therapy of episodic and chronic cluster headache with sumatriptan s.c. Results of a one-year long-term study]. ( Göbel, H; Heinze, A; Lindner, V; Pfaffenrath, V; Ribbat, M; Stolze, H, 1998)
" They are almost always benign, but can be mistaken for a serious adverse event by the patient."	1.30	The site of common side effects of sumatriptan. ( Lipton, RB; Newman, LC; Solomon, S, 1997)
"In seven cluster headache patients in whom nitroglycerin did not cause an attack, only an initial peak in MSA occurred."	1.30	Sympathetic vasoconstrictor outflow to extremity muscles in cluster headache. Recordings during spontaneous and nitroglycerin-induced attacks. ( Fagius, J; Nordin, M; Waldenlind, E, 1997)
"The pathophysiologies of migraine and cluster headache have a specific modifying property on cognitive processing reflected by a loss of cognitive habituation or an increased cognitive processing time."	1.30	Cognitive processing in primary headache: a study on event-related potentials. ( Bauer, B; Evers, S; Grotemeyer, KH; Husstedt, IW; Suhr, B, 1997)
"The findings support a scenario in cluster headache where an inflammation in the cavernous sinus affects the sympathetic fibers traversing the cavernous region."	1.29	Subcutaneous sumatriptan in cluster headache: a time study of the effect on pain and autonomic symptoms. ( Hardebo, JE, 1993)
"Sumatriptan was used in 232 attacks suffered by 16 patients and its effect was very rapid."	1.29	[Sumatriptan and cluster headache]. ( Alberca, R; Arenas, C; Casado, JL; Moreno, A; Serrano, V, 1995)
"Sumatriptan has shown to be effective in the treatment of an acute migraine- and cluster-headache."	1.29	[Sumatriptan--side effects and problems in routine clinical practice]. ( Aull, S; Marterer, A; Schnider, P; Wessely, P; Wöber, C, 1995)
" The patients described had a high frequency of attacks (more than two per day); therefore, far higher dosage of the drug was taken than commonly used in cluster headache."	1.29	Use of high sumatriptan dosages during episodic cluster headache: three clinical cases. ( Albano, O; Attolini, E; Bassi, A; Cassiano, MA; Cavazzuti, L; Centonze, V; Polito, BM; Ricchhetti, G; Sabbà, C, 1996)
"A patient was seen with secondary cluster headache whose acute pain responded promptly to sumatriptan."	1.29	Secondary cluster headache responsive to sumatriptan. ( Cremer, PD; Goadsby, PJ; Halmagyi, GM, 1995)
"It is well established that cluster headache shows impaired functions at the neuroimmunomodulatory system level."	1.29	Is the unresponsiveness to sumatriptan in cluster headache related to an alteration in the 5-HT receptors? ( Fusco, BM; Giacovazzo, M; Martelletti, P; Rinaldi, C; Stirparo, G, 1993)
"The increase obtained in migraine after ergotamine is more evident than that obtained in cases of cluster headache."	1.29	Upregulated expression of peripheral serotonergic receptors in migraine and cluster headache by sumatriptan. ( Giacovazzo, M; Martelletti, P; Rinaldi, C; Stirparo, G, 1994)
"All major controlled trials in migraine employed a parallel group design to avoid carryover effects and to ensure blinding was not compromised; however, because of the rarity of cluster headache, a crossover trial was performed in this indication."	1.28	Methodology of clinical trials of sumatriptan in migraine and cluster headache. ( Pilgrim, AJ, 1991)

Research

Studies (154)

Authors

Clinical Trials (2)

Trial Overview

Trial Outcomes

Change in Number of Absence Seizures From Week 8 (Baseline) to Week 12

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	63 (40.91)	18.2507
2000's	54 (35.06)	29.6817
2010's	23 (14.94)	24.3611
2020's	14 (9.09)	2.80

Authors	Studies
Diener, HC	5
May, A	4
Medrea, I	1
Christie, S	1
Tepper, SJ	2
Thavorn, K	1
Hutton, B	1
Panda, PK	1
Ramachandran, A	1
Sharawat, IK	1
Bhat, NK	1
Evers, S	4
Goadsby, PJ	10
Leone, M	7
Manzoni, GC	2
Pascual, J	3
Carvalho, V	1
Romoli, M	1
Aleksovska, K	1
Pozo-Rosich, P	1
Jensen, RH	3
Peng, KP	1
Burish, MJ	1
Belvis, R	1
Rodríguez, R	1
Guasch, M	1
Álvarez, MJ	1
Molet, J	1
Roig, C	1
Muzzi, M	1
Zecchi, R	1
Ranieri, G	1
Urru, M	1
Tofani, L	1
De Cesaris, F	1
Panconesi, A	1
Chiarugi, A	1
Holland, PR	1
Sureda-Gibert, P	1
Vila-Pueyo, M	1
Kikui, S	1
Sugiyama, H	1
Danno, D	1
Kashiwaya, Y	1
Takeshima, T	1
Wenzel, R	1
Smith, TR	1
Clark, AS	1
Petersen, AS	1
Lund, N	1
Barloese, M	1
Drescher, J	1
Khouri, A	1
Amann, TK	1
Gaul, C	1
Kropp, P	1
Siebenhaar, Y	1
Scheidt, J	1
Bastos, SNMAN	1
Barbosa, BLF	1
Silva, SF	1
Krymchantowski, AG	1
Jevoux, C	1
Krymchantowski, A	1
Silva-Néto, RP	1
Giustiniani, A	1
Cecchini, AP	3
Schindler, EAD	1
Wright, DA	1
Weil, MJ	1
Gottschalk, CH	1
Pittman, BP	1
Sico, JJ	1
Ishii, M	1
Katoh, H	1
Imawaka, M	1
Kasai, H	1
Ishibashi, M	1
Rossi, P	1
De La Torre, ER	1
Mitsikostas, D	1
Di Lorenzo, C	1
Palmaro, A	1
Benoliel, R	1
Eliav, E	1
Shimizu, T	1
Owada, K	1
Law, S	2
Derry, S	2
Moore, RA	2
Proietti Cecchini, A	2
Manne, JR	1
Donnet, A	1
Valade, D	1
Fontaine, D	1
De Pue, A	1
Lutin, B	1
Paemeleire, K	1
Verslegers, WR	2
Dodick, DW	1
Morelli, N	1
Pesaresi, I	1
Cafforio, G	1
Maluccio, MR	1
Gori, S	1
Di Salle, F	1
Murri, L	1
Tyagi, A	1
Matharu, M	2
Nissilä, M	1
Franzini, A	2
Mea, E	2
Broggi, G	2
Bussone, G	3
Mampreso, E	1
Maggioni, F	3
Viaro, F	1
Disco, C	1
Zanchin, G	3
Marmura, MJ	1
Pello, SJ	1
Young, WB	1
Tfelt-Hansen, P	1
Freitag, FG	1
Baskar, S	1
Etti, R	1
Kitas, G	1
Klocke, R	1
Frampton, JE	1
Pageler, L	1
Limmroth, V	1
Nesbitt, AD	1
Tfelt-Hansen, PC	1
Lionetto, L	1
Negro, A	1
Casolla, B	1
Simmaco, M	1
Martelletti, P	3
George, JS	1
Adams, W	1
Sadler, M	1
Weatherby, SJ	1
Ellis, P	1
Boes, CJ	1
van Vliet, JA	1
Bahra, A	3
Martin, V	1
Ramadan, N	1
Aurora, SK	1
Mathew, NT	4
Ferrari, MD	6
Markley, HG	1
Petzold, GC	1
Dreier, JP	1
Einhäupl, KM	2
Arnold, G	2
Pinessi, L	1
Rainero, I	1
Valfrè, W	1
Lo Giudice, R	1
Ferrero, M	1
Rivoiro, C	1
Arvat, E	1
Gianotti, L	1
Del Rizzo, P	1
Limone, P	1
Lisotto, C	2
Mainardi, F	2
Mir, P	1
Alberca, R	5
Navarro, A	1
Montes, E	1
Martínez, E	1
Franco, E	1
Cayuela, A	1
Lozano, P	1
D'Andrea, G	1
Terrazzino, S	1
Leon, A	1
Fortin, D	1
Perini, F	2
Granella, F	1
Rapoport, AM	1
Bigal, ME	1
Sheftell, FD	1
Torelli, P	1
Rozen, TD	2
Watanabe, M	1
Oda, A	1
Gregor, N	1
Schlesiger, C	1
Akova-Oztürk, E	1
Kraemer, C	1
Husstedt, IW	2
Gupta, VK	1
Fabre, N	2
Adams, SM	1
Standridge, JB	1
Favier, I	2
Haan, J	3
Dainese, F	1
Anghileri, E	1
Toso, V	1
Pickut, BA	1
De Deyn, PP	1
de L Figuerola, M	1
Bruera, O	1
Lestón, J	1
Ferreiro, J	1
Fanciullacci, M	2
Schürks, M	1
Kurth, T	1
de Jesus, J	1
Jonjic, M	1
Rosskopf, D	1
Afra, J	1
Linde, M	1
Sándor, PS	1
van Duinen, SG	1
Barbanti, P	2
Fabbrini, G	1
Berardelli, A	1
Rosenberg-Nordmann, M	1
Tölle, TR	1
Sprenger, T	1
Cohen, AS	1
Láinez, JM	2
Monzón, MJ	1
Cremer, PD	1
Halmagyi, GM	1
Stirparo, G	2
Fusco, BM	1
Giacovazzo, M	2
Rinaldi, C	2
Plosker, GL	1
McTavish, D	1
Alessandri, M	1
Figini, M	1
Geppetti, P	1
Michelacci, S	1
Stovner, LJ	2
Sjaastad, O	1
Ekbom, K	5
Krabbe, A	1
Micieli, G	1
Prusinski, A	3
Cole, JA	2
Pilgrim, AJ	3
Noronha, D	2
Micelli G [corrected to Micieli, G]	1
Moreno, A	2
Serrano, V	2
Casado, JL	2
Arenas, C	2
López, JM	1
Aguilera, JM	1
Kolosova, OA	1
Osipova, VV	1
Khomak, EB	1
Bobeĭko, LA	1
Dahlöf, C	2
Persson, L	1
Baumhackl, U	1
Kumar, KL	1
Ottervanger, JP	2
Paalman, HJ	1
Boxma, GL	1
Stricker, BH	2
Scott, AB	1
Poe, TE	1
Hardebo, JE	3
Visser, WH	1
Saxena, PR	2
Bax, WA	1
Mulder, LJ	1
Monstad, I	1
Wilkinson, M	1
Pfaffenrath, V	3
Schoenen, J	1
Steiner, TJ	1
Titus, F	1
Marterer, A	2
Wöber, C	2
Schnider, P	1
Aull, S	1
Wessely, P	2
Centonze, V	1
Polito, BM	1
Attolini, E	1
Cassiano, MA	1
Sabbà, C	1
Ricchhetti, G	1
Bassi, A	1
Cavazzuti, L	1
Albano, O	1
Valkenburg, HA	1
Grobbee, DE	1
Loi, V	1
Lai, M	1
Pisano, MR	1
Del Zompo, M	1
Bauer, B	1
Suhr, B	1
Grotemeyer, KH	2
Alla, P	1
Carli, P	1
Paris, JF	1
Ridderikhoff, J	1
Koudstaal, PJ	1
Solomon, S	2
Lipton, RB	1
Newman, LC	1
Nordin, M	1
Fagius, J	1
Waldenlind, E	2
Frid, A	1
Swain, RA	1
Kaplan, B	1
Scheen, AJ	1
Riess, CM	1
Becker, WJ	1
Robertson, M	1
Göbel, H	2
Lindner, V	2
Ribbat, M	2
Heinze, A	2
Stolze, H	1
Perry, CM	1
Markham, A	1
Frey, B	1
Zeiler, K	1
Quijano, J	1
Deuschl, G	1
Gaist, D	1
Cerbo, R	1
Pascali, M	1
Buzzi, MG	1
Pini, LA	1
Morelli, G	1
Millson, DS	1
Hering-Hanit, R	1
Evans, RW	1
Flote, VG	1
Gilhus, NE	1
Pradalier, A	1
Baudesson, G	1
Vincent, D	1
Imberty-Campinos, C	1
Zakrzewska, JM	1
Wiedemann, B	1
Leira, EC	1
Cruz-Flores, S	1
Leacock, RO	1
Abdulrauf, SI	1
Turhal, NS	1
Charlesworth, B	1
Schuh-Hofer, S	1
Reuter, U	1
Kinze, S	1
Hagen, K	1
Waage, A	1
Bjerve, KS	1
Soyka, D	1
Cole, J	1
Pilgrim, A	1
Kirkham, A	1
Tidswell, P	1
Hsu, VD	1
Arnold, WS	1
Dechant, KL	1
Clissold, SP	1
Raskin, NH	1
Peroutka, SJ	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Therapeutic Management of Acute Cephalalgia Before and After Use of a Therapeutic Protocol in Emergency Department[NCT02236442]		200 participants (Actual)	Interventional	2014-10-31	Completed
Verapamil as Adjunctive Seizure Therapy for Children and Young Adults With Dravet Syndrome[NCT01607073]	Phase 2	2 participants (Actual)	Interventional	2012-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

The secondary outcome measure is the change in number of absence seizures from Week 8 (Baseline) to Week 12 (NCT01607073)
Timeframe: Week 8 to Week 12

Change in Number of General Tonic-clonic Seizures From Week 8 (Baseline) Visit to Week 12 Visit

Intervention	Abscence seizures (Number)
Week 8 Baseline	165
Week 12 Verapamil 4mg/kg/Day	101

The primary study endpoint is the change in number of seizures from baseline. Since we only had one participant finish the study, the endpoint was changed to Week 12 visit. Participants were on verapamil for 4 weeks at Week 12. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12

Change in Number of Myoclonic Seizures From Week 8 (Baseline) to Week 12

Intervention	General tonic-clonic seizures (Number)
Week 8 Baseline	39
Week 12 Verapamil 4mg/kg/Day	14

The secondary outcome is the change in number of myoclonic seizures between baseline Week 8 visit and Week 12 visit. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12

Article	Year
Drug Treatment of Cluster Headache. Drugs, 2022, Volume: 82, Issue:1 Topics: Cluster Headache; Drug Administration Routes; Humans; Lithium; Oxazolidinones; Oxygen Inhalation The	2022
Network meta-analysis of therapies for cluster headache: Effects of acute therapies for episodic and chronic cluster. Headache, 2022, Volume: 62, Issue:4 Topics: Adolescent; Adult; Bayes Theorem; Cluster Headache; Headache; Humans; Nasal Sprays; Network Meta-Ana	2022
European Academy of Neurology guidelines on the treatment of cluster headache. European journal of neurology, 2023, Volume: 30, Issue:10 Topics: Cluster Headache; Humans; Oxygen; Quality of Life; Sumatriptan	2023
Management of cluster headache: Treatments and their mechanisms. Cephalalgia : an international journal of headache, 2023, Volume: 43, Issue:8 Topics: Autonomic Nervous System; Cluster Headache; Drug-Related Side Effects and Adverse Reactions; Humans;	2023
Cluster headache in children and adolescents: a systematic review of case reports. Developmental medicine and child neurology, 2021, Volume: 63, Issue:10 Topics: Adolescent; Adrenal Cortex Hormones; Blepharoptosis; Child; Child, Preschool; Cluster Headache; Gaba	2021
Cluster headache: present and future therapy. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:Suppl 1 Topics: Animals; Calcitonin Gene-Related Peptide; Cluster Headache; Electric Stimulation Therapy; Forecastin	2017
Primary headache disorders. Dental clinics of North America, 2013, Volume: 57, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Chronic Disease; Cluster Headache; Cycloox	2013
[New treatments for cluster headache]. Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11 Topics: Administration, Intranasal; Calcium Channel Blockers; Cluster Headache; Deep Brain Stimulation; Dexa	2013
Triptans for acute cluster headache. The Cochrane database of systematic reviews, 2013, Jul-17, Issue:7 Topics: Cluster Headache; Humans; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor	2013
[Cluster headache treatment]. Presse medicale (Paris, France : 1983), 2015, Volume: 44, Issue:11 Topics: Acute Disease; Cluster Headache; Deep Brain Stimulation; Electric Stimulation Therapy; Humans; Lithi	2015
Evidence base for the medical treatments used in cluster headache. Current pain and headache reports, 2009, Volume: 13, Issue:2 Topics: Cluster Headache; Evidence-Based Medicine; Humans; Nerve Block; Octreotide; Oxazolidinones; Oxygen;	2009
Triptans for acute cluster headache. The Cochrane database of systematic reviews, 2010, Apr-14, Issue:4 Topics: Cluster Headache; Humans; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor	2010
Sumatriptan needle-free subcutaneous (Sumavel(®) DosePro™) approved for the acute treatment of migraine, with or without aura, and cluster headaches. Expert review of neurotherapeutics, 2011, Volume: 11, Issue:4 Topics: Cluster Headache; Drug Administration Routes; Drug Delivery Systems; Female; Humans; Injections, Sub	2011
Cluster headache. BMJ clinical evidence, 2010, Feb-09, Volume: 2010 Topics: Adrenal Cortex Hormones; Betamethasone; Cluster Headache; Humans; Methysergide; Oxygen; Sumatriptan	2010
Needle-free subcutaneous sumatriptan: in the acute treatment of migraine attacks or cluster headache episodes. CNS drugs, 2011, Nov-01, Volume: 25, Issue:11 Topics: Clinical Trials, Phase IV as Topic; Cluster Headache; Drug Delivery Systems; Humans; Infusions, Subc	2011
Oral triptans in the preventive management of cluster headache. Current pain and headache reports, 2012, Volume: 16, Issue:2 Topics: Administration, Oral; Cluster Headache; Female; Humans; Male; Oxygen Inhalation Therapy; Practice Gu	2012
Cluster headache. BMJ (Clinical research ed.), 2012, Apr-11, Volume: 344 Topics: Cluster Headache; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Humans; M	2012
Sumatriptan succinate : pharmacokinetics of different formulations in clinical practice. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:16 Topics: Animals; Cluster Headache; Humans; Migraine Disorders; Serotonin 5-HT1 Receptor Agonists; Sumatripta	2012
Zolmitriptan: differences from sumatriptan. Current medical research and opinion, 2001, Volume: 17 Suppl 1 Topics: Cluster Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatript	2001
Topical agents in the treatment of cluster headache. Current pain and headache reports, 2003, Volume: 7, Issue:2 Topics: Administration, Intranasal; Administration, Topical; Capsaicin; Cluster Headache; Cocaine; Dihydroer	2003
Intranasal medications for the treatment of migraine and cluster headache. CNS drugs, 2004, Volume: 18, Issue:10 Topics: Administration, Intranasal; Analgesics; Capsaicin; Cluster Headache; Humans; Migraine Disorders; Oxa	2004
Cluster headache: diagnosis and treatment. Current neurology and neuroscience reports, 2005, Volume: 5, Issue:2 Topics: Analgesics; Cluster Headache; Ergotamine; Humans; Sumatriptan	2005
[Treatment of cluster headache]. Revue neurologique, 2005, Volume: 161, Issue:6-7 Topics: Cluster Headache; Facial Pain; Headache; Humans; Oxygen Inhalation Therapy; Sumatriptan; Trigeminal	2005
Practical strategy for detecting and relieving cluster headaches. The Journal of family practice, 2005, Volume: 54, Issue:12 Topics: Cluster Headache; Humans; Oxygen; Serotonin Receptor Agonists; Sumatriptan; Vasodilator Agents; Vera	2005
Chronic cluster headache: a review. The journal of headache and pain, 2005, Volume: 6, Issue:1 Topics: Autonomic Nervous System Diseases; Causality; Cluster Headache; Demography; Humans; Hypothalamus; Or	2005
EFNS guidelines on the treatment of cluster headache and other trigeminal-autonomic cephalalgias. European journal of neurology, 2006, Volume: 13, Issue:10 Topics: Advisory Committees; Analgesics; Clinical Trials as Topic; Cluster Headache; Europe; Humans; Lithium	2006
[Trigeminal autonomic cephalgias: diagnostic and therapeutic implications]. MMW Fortschritte der Medizin, 2007, Sep-06, Volume: 149, Issue:35-36 Topics: Administration, Intranasal; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cluster Headac	2007
[Pathophysiology and treatment of trigeminal autonomic cephalalgias]. Schmerz (Berlin, Germany), 2008, Volume: 22 Suppl 1 Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroida	2008
[Sumatriptan ++ in the treatment of migraine and cluster headache]. Revista de neurologia, 1995, Volume: 23 Suppl 2 Topics: Adolescent; Adult; Aged; Blood Proteins; Brain; Cluster Headache; Female; Humans; Kidney; Liver; Mal	1995
Sumatriptan. A reappraisal of its pharmacology and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs, 1994, Volume: 47, Issue:4 Topics: Administration, Oral; Animals; Cluster Headache; Humans; Injections, Subcutaneous; Migraine Disorder	1994
Treatment of cluster headache and its variants. Current opinion in neurology, 1995, Volume: 8, Issue:3 Topics: Cluster Headache; Humans; Hyperbaric Oxygenation; Injections, Subcutaneous; Migraine Disorders; Sero	1995
The clinical profile of sumatriptan: cluster headache. European neurology, 1994, Volume: 34 Suppl 2 Topics: Cluster Headache; Combined Modality Therapy; Female; Humans; Injections, Subcutaneous; Long-Term Car	1994
Clinical experiences from Sweden on the use of subcutaneously administered sumatriptan in migraine and cluster headache. Archives of neurology, 1994, Volume: 51, Issue:12 Topics: Cardiovascular Diseases; Central Nervous System Diseases; Cluster Headache; Humans; Injections, Subc	1994
[Therapy of migraine with special reference to sumatriptan]. Wiener medizinische Wochenschrift (1946), 1994, Volume: 144, Issue:5-6 Topics: Cluster Headache; Drug Interactions; Humans; Migraine Disorders; Receptors, Serotonin; Sumatriptan	1994
Recent advances in the acute management of migraine and cluster headaches. Journal of general internal medicine, 1994, Volume: 9, Issue:6 Topics: Analgesics; Butorphanol; Capsaicin; Cluster Headache; Dihydroergotamine; Humans; Ketorolac; Metoclop	1994
[Sumatriptan in clinical practice]. Nederlands tijdschrift voor geneeskunde, 1993, Apr-24, Volume: 137, Issue:17 Topics: Adolescent; Adult; Child; Cluster Headache; Humans; Indoles; Migraine Disorders; Myocardial Ischemia	1993
Migraine and cluster headache--their management with sumatriptan: a critical review of the current clinical experience. Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:5 Topics: Clinical Trials as Topic; Cluster Headache; Humans; Migraine Disorders; Serotonin Receptor Agonists;	1995
[Symptomatic treatment of cluster headache]. Revista de neurologia, 1995, Volume: 23 Suppl 4 Topics: Alkaloids; Analgesics; Capsaicin; Cluster Headache; Cocaine; Dihydroergotamine; Ergotamine; Humans;	1995
Treatment of cluster headache: clinical trials, design and results. Cephalalgia : an international journal of headache, 1995, Volume: 15 Suppl 15 Topics: Adolescent; Adult; Aged; Child; Cluster Headache; Double-Blind Method; Female; Humans; Long-Term Car	1995
Serotonin 1D (5-HT1D) agonists and other agents in acute migraine. Neurologic clinics, 1997, Volume: 15, Issue:1 Topics: Acute Disease; Analgesics, Non-Narcotic; Cluster Headache; Dihydroergotamine; Drug Interactions; Hum	1997
Diagnosis, prophylaxis, and treatment of headaches in the athlete. Southern medical journal, 1997, Volume: 90, Issue:9 Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic;	1997
[Unusual varieties of cluster headache]. Neurologia (Barcelona, Spain), 1997, Volume: 12 Suppl 5 Topics: Adolescent; Adult; Aged; Cluster Headache; Female; Humans; Male; Middle Aged; Sumatriptan; Vasoconst	1997
Sumatriptan. An updated review of its use in migraine. Drugs, 1998, Volume: 55, Issue:6 Topics: Administration, Intranasal; Administration, Oral; Administration, Rectal; Cerebrovascular Circulatio	1998
Cardiac effects of sumatriptan: findings of Holter monitoring and review of the literature. Wiener klinische Wochenschrift, 1998, May-08, Volume: 110, Issue:9 Topics: Adult; Aged; Arrhythmias, Cardiac; Cluster Headache; Electrocardiography, Ambulatory; Female; Humans	1998
Cluster headache: management of acute attacks before triptans. Italian journal of neurological sciences, 1999, Volume: 20, Issue:2 Suppl Topics: Acute Disease; Cluster Headache; Ergotamine; Humans; Oxygen; Sumatriptan; Vasoconstrictor Agents	1999
Triptans: turning treatment in cluster headache attack. Italian journal of neurological sciences, 1999, Volume: 20, Issue:2 Suppl Topics: Cluster Headache; Humans; Sumatriptan; Vasoconstrictor Agents	1999
How effective are triptans in the treatment of episodic and chronic cluster headache. Italian journal of neurological sciences, 1999, Volume: 20, Issue:2 Suppl Topics: Chronic Disease; Cluster Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Su	1999
[Treatment of cluster headache]. Revue neurologique, 2000, Volume: 156 Suppl 4 Topics: Cluster Headache; Ergotamine; Glucocorticoids; Humans; Lithium; Melatonin; Methysergide; Oxygen Inha	2000
[Treatment of cluster headache]. La Revue de medecine interne, 2001, Volume: 22, Issue:2 Topics: Anti-Inflammatory Agents; Calcium Channel Blockers; Chronic Disease; Cluster Headache; Combined Moda	2001
Cluster headache: review of the literature. The British journal of oral & maxillofacial surgery, 2001, Volume: 39, Issue:2 Topics: Anticonvulsants; Clinical Protocols; Cluster Headache; Diagnosis, Differential; Humans; Migraine Dis	2001
New treatments in cluster headache. Current neurology and neuroscience reports, 2002, Volume: 2, Issue:2 Topics: Anesthetics, Local; Benzodiazepines; Cluster Headache; Ergotamine; Humans; Lidocaine; Olanzapine; Ox	2002
Clinical effects and mechanism of action of sumatriptan in migraine. Clinical neurology and neurosurgery, 1992, Volume: 94 Suppl Topics: Animals; Brain; Cluster Headache; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disord	1992
Sumatriptan: a new drug for vascular headache. Clinical pharmacy, 1992, Volume: 11, Issue:11 Topics: Cluster Headache; Humans; Indoles; Migraine Disorders; Serotonin Receptor Agonists; Sulfonamides; Su	1992
[Sumatriptan and its use in treatment of migraine and cluster headaches]. Neurologia i neurochirurgia polska, 1992, Volume: Suppl 2 Topics: Cluster Headache; Humans; Indoles; Migraine Disorders; Serotonin Receptor Agonists; Sulfonamides; Su	1992
[Sumatriptan--future development, alternative features and potential new indications]. Neurologia i neurochirurgia polska, 1992, Volume: Suppl 2 Topics: Administration, Oral; Cluster Headache; Humans; Indoles; Injections, Subcutaneous; Migraine Disorder	1992
Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs, 1992, Volume: 43, Issue:5 Topics: Acute Disease; Animals; Cluster Headache; Humans; Indoles; Migraine Disorders; Serotonin; Sulfonamid	1992
Sumatriptan in acute migraine: pharmacology and review of world experience. Headache, 1990, Volume: 30 Suppl 2 Topics: Acute Disease; Administration, Oral; Animals; Cluster Headache; Humans; Indoles; Injections, Subcuta	1990

Article	Year
Intranasal sumatriptan in cluster headache: randomized placebo-controlled double-blind study. Neurology, 2003, Feb-25, Volume: 60, Issue:4 Topics: Administration, Intranasal; Adult; Cluster Headache; Cohort Studies; Cross-Over Studies; Double-Blin	2003
Prophylactic treatment of episodic cluster headache with intravenous bolus of methylprednisolone. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24, Issue:5 Topics: Adult; Cluster Headache; Drug Administration Schedule; Drug Therapy, Combination; Ergotamine; Humans	2003
Treatment of cluster headache attacks with less than 6 mg subcutaneous sumatriptan. Headache, 2005, Volume: 45, Issue:8 Topics: Acute Disease; Administration, Inhalation; Adult; Cluster Headache; Combined Modality Therapy; Dose-	2005
Cluster headache attacks treated for up to three months with subcutaneous sumatriptan (6 mg). Sumatriptan Cluster Headache Long-term Study Group. Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:3 Topics: Adolescent; Adult; Aged; Cluster Headache; Female; Humans; Injections, Subcutaneous; Male; Middle Ag	1995
The clinical profile of sumatriptan: cluster headache. European neurology, 1994, Volume: 34 Suppl 2 Topics: Cluster Headache; Combined Modality Therapy; Female; Humans; Injections, Subcutaneous; Long-Term Car	1994
[Sumatriptan in the treatment of cluster headache and migraine attacks]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:5 Topics: Adult; Chronic Disease; Cluster Headache; Humans; Injections, Subcutaneous; Male; Middle Aged; Migra	1994
Subcutaneous sumatriptan in the acute treatment of cluster headache: a dose comparison study. The Sumatriptan Cluster Headache Study Group. Acta neurologica Scandinavica, 1993, Volume: 88, Issue:1 Topics: Adolescent; Adult; Aged; Cluster Headache; Cross-Sectional Studies; Dose-Response Relationship, Drug	1993
The thigh may not be suitable as an injection site for patients self-injecting sumatriptan. Neurology, 1997, Volume: 49, Issue:2 Topics: Adult; Aged; Buttocks; Cluster Headache; Female; Humans; Injections; Injections, Intramuscular; Male	1997
Acute therapy for cluster headache with sumatriptan: findings of a one-year long-term study. Neurology, 1998, Volume: 51, Issue:3 Topics: Adult; Cluster Headache; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Pain; Prospect	1998
Sumatriptan nasal spray (20 mg/dose) in the acute treatment of cluster headache. Cephalalgia : an international journal of headache, 1998, Volume: 18, Issue:7 Topics: Administration, Inhalation; Adult; Aged; Cluster Headache; Dose-Response Relationship, Drug; Female;	1998
Treatment of acute cluster headache with 20 mg sumatriptan nasal spray--an open pilot study. Journal of neurology, 2002, Volume: 249, Issue:1 Topics: Administration, Intranasal; Adult; Cluster Headache; Drug Tolerance; Genetic Variation; Humans; Male	2002
Sumatriptan in chronic cluster headache: results of continuous treatment for eleven months. Cephalalgia : an international journal of headache, 1992, Volume: 12, Issue:4 Topics: Adult; Chronic Disease; Cluster Headache; Double-Blind Method; Humans; Indoles; Injections, Subcutan	1992
Treatment of acute cluster headache with sumatriptan. The New England journal of medicine, 1991, 08-01, Volume: 325, Issue:5 Topics: Acute Disease; Adult; Cluster Headache; Double-Blind Method; Drug Tolerance; Female; Humans; Indoles	1991

Article	Year
Feasibility, Utility, and Interrater Reliability of the Cluster Headache Severity Scale, Cluster Headache Quality of Life, Cluster Headache Index, and 6-Item Headache Impact Test in Pediatric Cluster Headache. Journal of child neurology, 2022, Volume: 37, Issue:10-11 Topics: Child; Cluster Headache; Feasibility Studies; Female; Headache; Humans; Male; Nasal Sprays; Predniso	2022
Efficacy and safety of surgical treatment of cluster headache. Medicina clinica, 2020, 02-14, Volume: 154, Issue:3 Topics: Adult; Cluster Headache; Deep Brain Stimulation; Denervation; Electric Stimulation Therapy; Female;	2020
Ultra-rapid brain uptake of subcutaneous sumatriptan in the rat: Implication for cluster headache treatment. Cephalalgia : an international journal of headache, 2020, Volume: 40, Issue:4 Topics: Animals; Brain; Chromatography, Liquid; Cluster Headache; Injections, Subcutaneous; Male; Mass Spect	2020
Rapid uptake of sumatriptan into the brain: An ongoing question of blood-brain barrier permeability. Cephalalgia : an international journal of headache, 2020, Volume: 40, Issue:4 Topics: Animals; Blood-Brain Barrier; Brain; Cluster Headache; Permeability; Rats; Sumatriptan	2020
Chronic Cluster Headache with a Pediatric Onset: The First Japanese Case Report. Internal medicine (Tokyo, Japan), 2020, Nov-15, Volume: 59, Issue:22 Topics: Child; Cluster Headache; Female; Humans; Japan; Sumatriptan; Verapamil	2020
Cluster Headache: Opportunities for Pharmacists to Improve Care. Journal of pharmacy practice, 2022, Volume: 35, Issue:2 Topics: Cluster Headache; Humans; Oxygen; Pain; Pharmacists; Sumatriptan	2022
Real-life treatment of cluster headache in a tertiary headache center - results from the Danish Cluster Headache Survey. Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:5 Topics: Cluster Headache; Cross-Sectional Studies; Denmark; Headache; Humans; Oxygen; Sumatriptan; Surveys a	2021
Effectiveness of medication in cluster headache. BMC neurology, 2021, Apr-22, Volume: 21, Issue:1 Topics: Cluster Headache; Humans; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines	2021
Survey Analysis of the Use, Effectiveness, and Patient-Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster Headache. Headache, 2018, Volume: 58, Issue:10 Topics: Adult; Aged; Alcohol Drinking; Cluster Headache; Female; Health Care Surveys; Humans; Injections, Su	2018
[Therapeutic Effects of Intranasal Sumatriptan for Cluster Headache]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:1 Topics: Administration, Intranasal; Adolescent; Adult; Age Factors; Age of Onset; Child; Cluster Headache; F	2019
Availability of Effective Evidence-Based Symptomatic Treatments for Cluster Headache in the EU Countries-A Survey of the European Headache Alliance and European Headache Federation. Journal of oral & facial pain and headache, 2020,Winter, Volume: 34, Issue:1 Topics: Cluster Headache; European Union; Headache; Humans; Sumatriptan; Surveys and Questionnaires	2020
[Therapeuetic aspects of cluster headache in the practical clinical site]. Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11 Topics: Adult; Amines; Amitriptyline; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Therapy, Combinati	2013
Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache. Neurology, 2016, Jan-12, Volume: 86, Issue:2 Topics: Adult; Aged; Chronic Pain; Cluster Headache; Drug Resistance; Female; Humans; Injections, Subcutaneo	2016
Cluster Syncope. The American journal of medicine, 2016, Volume: 129, Issue:2 Topics: Analgesics, Opioid; Bradycardia; Cluster Headache; Electrocardiography; Humans; Male; Middle Aged; O	2016
Chronic cluster headache and the pituitary gland. The journal of headache and pain, 2016, Volume: 17 Topics: Adenoma; Cabergoline; Central Nervous System Cysts; Cluster Headache; Diagnosis, Differential; Dopam	2016
Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache. Neurology, 2016, 10-04, Volume: 87, Issue:14 Topics: Cluster Headache; Humans; Injections, Subcutaneous; Substance-Related Disorders; Sumatriptan	2016
CASE 1: the well-intentioned triptan prescriber. Headache, 2008, Volume: 48, Issue:6 Topics: Cluster Headache; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Malpractice; Middle	2008
New therapies may ease headache symptoms. A two-drug combo and two kinds of oxygen therapy show promise for relieving migraine and cluster headache pain. DukeMedicine healthnews, 2008, Volume: 14, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cluster Headache; Drug Therapy, C	2008
Functional magnetic resonance imaging in episodic cluster headache. The journal of headache and pain, 2009, Volume: 10, Issue:1 Topics: Adult; Cluster Headache; Echo-Planar Imaging; Functional Laterality; Humans; Hypothalamus; Injection	2009
[Cluster headache]. Duodecim; laaketieteellinen aikakauskirja, 2009, Volume: 125, Issue:1 Topics: Administration, Intranasal; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Cluster Headache; Erg	2009
Costs of hypothalamic stimulation in chronic drug-resistant cluster headache: preliminary data. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2009, Volume: 30 Suppl 1 Topics: Adult; Cluster Headache; Deep Brain Stimulation; Drug Resistance; Electronics, Medical; Female; Foll	2009
Efficacy of oxygen inhalation in sumatriptan refractory "high altitude" cluster headache attacks. The journal of headache and pain, 2009, Volume: 10, Issue:6 Topics: Adult; Altitude Sickness; Atmospheric Pressure; Calcium Channel Blockers; Cluster Headache; Drug Res	2009
Interictal pain in cluster headache. Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:12 Topics: Adult; Aged; Cluster Headache; Female; Humans; Male; Middle Aged; Pain; Sumatriptan; Surveys and Que	2010
Effective symptomatic medication should be available in prophylactic trials in cluster headache. Headache, 2011, Volume: 51, Issue:2 Topics: Carbazoles; Cluster Headache; Guidelines as Topic; Humans; Randomized Controlled Trials as Topic; Se	2011
Cluster headache or giant cell arteritis? BMJ case reports, 2008, Volume: 2008 Topics: Aged; Anti-Inflammatory Agents; Cluster Headache; Diagnosis, Differential; Female; Giant Cell Arteri	2008
Management of cluster headache. CNS drugs, 2012, Jul-01, Volume: 26, Issue:7 Topics: Analgesics; Cluster Headache; Deep Brain Stimulation; Disease Management; Ergotamine; Fructose; Huma	2012
A case of 'cryptogenic' type D carotid cavernous fistula presenting initially with cluster-like headache. Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:7 Topics: Brain; Carotid-Cavernous Sinus Fistula; Cerebral Angiography; Cluster Headache; Embolization, Therap	2013
Cluster-like headache time-locked to the menstrual cycle. Neurology, 2003, Mar-25, Volume: 60, Issue:6 Topics: Acne Vulgaris; Adult; Cluster Headache; Cyproterone Acetate; Ethinyl Estradiol; Female; Humans; Mens	2003
Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with sumatriptan. Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:5 Topics: Adult; Analysis of Variance; Cluster Headache; Double-Blind Method; Female; Humans; Male; Middle Age	2003
Hemicrania continua with contralateral episodic cluster headache: a case report. Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:9 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Functional Laterality; Humans; Ind	2003
Diagnostic delays and mis-management in cluster headache. Acta neurologica Scandinavica, 2004, Volume: 109, Issue:3 Topics: Adolescent; Adult; Aged; Child; Cluster Headache; Databases, Factual; Diagnosis, Differential; Engla	2004
Elevated levels of circulating trace amines in primary headaches. Neurology, 2004, May-25, Volume: 62, Issue:10 Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cluster Headache; Diet; Female; Headache; H	2004
Cluster headache: symptomatic treatment. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3 Topics: Clinical Trials as Topic; Cluster Headache; Humans; Injections, Subcutaneous; Oxygen Inhalation Ther	2004
[Sumatriptan nasal spray for the treatment of cluster headache]. No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:1 Topics: Administration, Intranasal; Adult; Cluster Headache; Drug Administration Schedule; Humans; Male; Mid	2005
Change in frequency pattern in cluster headache induced by subcutaneous sumatriptan. Headache, 2005, Volume: 45, Issue:8 Topics: Cluster Headache; Humans; Injections, Subcutaneous; Recurrence; Serotonin Receptor Agonists; Sumatri	2005
Cluster-like headache after surgical crystalline removal and intraocular lens implant: a case report. The journal of headache and pain, 2005, Volume: 6, Issue:2 Topics: Anti-Inflammatory Agents; Brain; Cataract Extraction; Cerebral Angiography; Cluster Headache; Functi	2005
Acute myocardial infarction after sumatriptan administration for cluster headache. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2006, Volume: 26, Issue:6 Topics: Adult; Cluster Headache; Humans; Male; Myocardial Infarction; Sumatriptan; Vasoconstrictor Agents	2006
Paroxysmal neuralgic upper cervical pain attacks: the lower syndrome of cluster headache. Clinical neurology and neurosurgery, 2006, Volume: 108, Issue:8 Topics: Adult; Aged; Anticonvulsants; Cluster Headache; Combined Modality Therapy; Diagnosis, Differential;	2006
Cluster headache attack due to sildenafil intake. Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:5 Topics: Cluster Headache; Humans; Lithium; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Pur	2006
When cluster headache was called histaminic cephalalgia (Horton's headache). The journal of headache and pain, 2006, Volume: 7, Issue:4 Topics: Anisocoria; Brain; Cerebral Arteries; Cluster Headache; Histamine; History, 20th Century; Humans; Ne	2006
Cluster headache: clinical presentation, lifestyle features, and medical treatment. Headache, 2006, Volume: 46, Issue:8 Topics: Adult; Alcoholic Beverages; Cluster Headache; Female; Humans; Male; Oxygen; Prospective Studies; Ser	2006
Acute hypothalamic stimulation and ongoing cluster headache attacks. Neurology, 2006, Nov-28, Volume: 67, Issue:10 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Physiological Phenomena; Cerebr	2006
Typical cluster headache caused by granulomatous pituitary involvement. Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:2 Topics: Adult; Cluster Headache; Female; Granuloma; Humans; Magnetic Resonance Imaging; Pituitary Diseases;	2007
Acute pathological laughter induced by sumatriptan. Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:1 Topics: Adult; Basal Ganglia Diseases; Cluster Headache; Humans; Laughter; Male; Sumatriptan	2008
Secondary cluster headache responsive to sumatriptan. Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 59, Issue:6 Topics: Aged; Aortic Dissection; Cluster Headache; Humans; Male; Serotonin Receptor Agonists; Sumatriptan; V	1995
Is the unresponsiveness to sumatriptan in cluster headache related to an alteration in the 5-HT receptors? International journal of clinical pharmacology research, 1993, Volume: 13, Issue:5 Topics: Adult; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cluster Headache; Flow Cytometry; Hu	1993
Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack. Pain, 1995, Volume: 60, Issue:2 Topics: Adult; Calcitonin Gene-Related Peptide; Cluster Headache; Humans; Male; Nitroglycerin; Remission Ind	1995
Long-term subcutaneous sumatriptan in cluster headache. Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:3 Topics: Clinical Trials as Topic; Cluster Headache; Humans; Injections, Subcutaneous; Sumatriptan; Time Fact	1995
Upregulated expression of peripheral serotonergic receptors in migraine and cluster headache by sumatriptan. International journal of clinical pharmacology research, 1994, Volume: 14, Issue:5-6 Topics: Adult; Analysis of Variance; Binding, Competitive; Cluster Headache; Ergotamine; Female; Flow Cytome	1994
[Sumatriptan and cluster headache]. Neurologia (Barcelona, Spain), 1995, Volume: 10, Issue:2 Topics: Adolescent; Adult; Cluster Headache; Double-Blind Method; Female; Humans; Male; Middle Aged; Sumatri	1995
[Chronic cluster headache: course and outcome of treatment]. Neurologia (Barcelona, Spain), 1994, Volume: 9, Issue:9 Topics: Adrenal Cortex Hormones; Calcium Channel Blockers; Cluster Headache; Ergotamine; Humans; Indomethaci	1994
Transmural myocardial infarction with sumatriptan. Lancet (London, England), 1993, Apr-03, Volume: 341, Issue:8849 Topics: Cluster Headache; Electrocardiography; Exercise Test; Female; Heparin; Humans; Indoles; Injections,	1993
Correction of sumatriptan information. Journal of pain and symptom management, 1994, Volume: 9, Issue:1 Topics: Cluster Headache; Contraindications; Humans; Injections, Intramuscular; Injections, Intravenous; Sum	1994
Subcutaneous sumatriptan in cluster headache: a time study of the effect on pain and autonomic symptoms. Headache, 1993, Volume: 33, Issue:1 Topics: Adult; Aged; Autonomic Nervous System Diseases; Cluster Headache; Female; Humans; Indoles; Injection	1993
[Sumatriptan--side effects and problems in routine clinical practice]. Medizinische Klinik (Munich, Germany : 1983), 1995, Nov-15, Volume: 90, Issue:11 Topics: Adult; Cluster Headache; Contraindications; Dose-Response Relationship, Drug; Drug Administration Sc	1995
Use of high sumatriptan dosages during episodic cluster headache: three clinical cases. Headache, 1996, Volume: 36, Issue:6 Topics: Adult; Cluster Headache; Humans; Injections, Subcutaneous; Male; Middle Aged; Recurrence; Serotonin	1996
Pattern of sumatriptan use and overuse in general practice. European journal of clinical pharmacology, 1996, Volume: 50, Issue:5 Topics: Administration, Oral; Adult; Cluster Headache; Cohort Studies; Drug Utilization; Family Practice; Fe	1996
Sumatriptan and panic-like symptoms. The American journal of psychiatry, 1996, Volume: 153, Issue:11 Topics: Chest Pain; Cluster Headache; Humans; Migraine Disorders; Panic Disorder; Serotonin Receptor Agonist	1996
Cognitive processing in primary headache: a study on event-related potentials. Neurology, 1997, Volume: 48, Issue:1 Topics: Adolescent; Adult; Aged; Cluster Headache; Cognition; Evoked Potentials; Female; Habituation, Psycho	1997
[Horton disease, vascular pain of the face and sumatriptan]. La Revue de medecine interne, 1996, Volume: 17, Issue:12 Topics: Aged; Cluster Headache; Female; Giant Cell Arteritis; Humans; Serotonin Receptor Agonists; Sumatript	1996
[Subcutaneous sumatriptan in cluster headache: impossible mission]. Medicina clinica, 1997, Feb-22, Volume: 108, Issue:7 Topics: Cluster Headache; Humans; Injections, Subcutaneous; Serotonin Receptor Agonists; Sumatriptan; Vasoco	1997
[Cluster headache: misjudged because unknown]. Nederlands tijdschrift voor geneeskunde, 1997, Feb-15, Volume: 141, Issue:7 Topics: Adult; Analgesics; Calcium Channel Blockers; Cluster Headache; Diagnosis, Differential; Humans; Male	1997
The site of common side effects of sumatriptan. Headache, 1997, Volume: 37, Issue:5 Topics: Adult; Cluster Headache; Humans; Male; Migraine Disorders; Paresthesia; Sumatriptan; Vasoconstrictor	1997
Sympathetic vasoconstrictor outflow to extremity muscles in cluster headache. Recordings during spontaneous and nitroglycerin-induced attacks. Headache, 1997, Volume: 37, Issue:6 Topics: Adult; Animals; Baroreflex; Cluster Headache; Female; Humans; Male; Middle Aged; Muscles; Nitroglyce	1997
[Drug-clinics. The drug of the month. Imitrex nasal spray (sumatriptan)]. Revue medicale de Liege, 1997, Volume: 52, Issue:9 Topics: Administration, Intranasal; Administration, Oral; Cluster Headache; Humans; Injections, Subcutaneous	1997
Episodic cluster headache in a community: clinical features and treatment. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1998, Volume: 25, Issue:2 Topics: Adaptation, Psychological; Adult; Aged; Analgesics; Cluster Headache; Dihydroergotamine; Emergency S	1998
[Acute therapy of episodic and chronic cluster headache with sumatriptan s.c. Results of a one-year long-term study]. Der Nervenarzt, 1998, Volume: 69, Issue:4 Topics: Acute Disease; Adult; Cluster Headache; Female; Humans; Injections, Subcutaneous; Long-Term Care; Ma	1998
A case of chronic paroxysmal hemicrania responding to subcutaneous sumatriptan. Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 65, Issue:3 Topics: Adult; Chronic Disease; Cluster Headache; Female; Humans; Injections, Subcutaneous; Migraine Disorde	1998
Use and overuse of sumatriptan. Pharmacoepidemiological studies based on prescription register and interview data. Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:8 Topics: Cluster Headache; Denmark; Drug Prescriptions; Female; Humans; Interviews as Topic; Male; Migraine D	1999
Alteration in nature of cluster headache during subcutaneous administration of sumatriptan. Headache, 2000, Volume: 40, Issue:1 Topics: Adult; Chronic Disease; Cluster Headache; Headache; Humans; Injections, Subcutaneous; Male; Middle A	2000
What are cluster headaches and how are they treated? Health news (Waltham, Mass.), 2000, Volume: 6, Issue:7 Topics: Cluster Headache; Humans; Oxygen Inhalation Therapy; Sumatriptan	2000
Is it migraine or cluster? Headache, 2000, Volume: 40, Issue:8 Topics: Adult; Calcium Channel Blockers; Cluster Headache; Diagnosis, Differential; Female; Humans; Migraine	2000
[Patients with cluster headache in a neurological department]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Nov-30, Volume: 120, Issue:29 Topics: Adult; Aged; Chronic Disease; Cluster Headache; Female; Hospitalization; Humans; Male; Middle Aged;	2000
[Aspirin, triptan tablet, nasal spray, injection. Even the most severe migraine capitulates]. MMW Fortschritte der Medizin, 2001, Apr-19, Volume: 143, Issue:16 Topics: Administration, Intranasal; Aspirin; Cluster Headache; Humans; Injections, Intravenous; Injections,	2001
Sumatriptan can alleviate headaches due to carotid artery dissection. Headache, 2001, Volume: 41, Issue:6 Topics: Carotid Artery Diseases; Cluster Headache; Diagnosis, Differential; False Positive Reactions; Humans	2001
Sumatriptan overdose in episodic cluster headache: a case report of overuse without event. Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:6 Topics: Acute Disease; Adult; Cluster Headache; Drug Overdose; Humans; Male; Sumatriptan; Vasoconstrictor Ag	2001
Sumatriptan in the treatment of cluster headache. Cephalalgia : an international journal of headache, 2001, Volume: 21 Suppl 1 Topics: Clinical Trials as Topic; Cluster Headache; Humans; Injections, Subcutaneous; Sumatriptan; Treatment	2001
Cluster headache: a prospective clinical study with diagnostic implications. Neurology, 2002, Feb-12, Volume: 58, Issue:3 Topics: Adolescent; Adult; Aged; Child; Cluster Headache; Contraceptives, Oral; Estrogen Replacement Therapy	2002
Re: Zakrzewska JM. Cluster headache: review of the literature. Br J Oral Maxillofac Surg 2001; 39: 103-113. The British journal of oral & maxillofacial surgery, 2002, Volume: 40, Issue:1 Topics: Administration, Oral; Cluster Headache; Humans; Injections, Subcutaneous; Oxazolidinones; Serotonin	2002
Hereditary haemochromatosis in two cousins with cluster headache. Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:4 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Stem; Calcium Channel Blockers; Cluster Headac	2002
[Treatment of cluster headache. Recommendations of the German Migraine and Headache Society]. Medizinische Monatsschrift fur Pharmazeuten, 1992, Volume: 15, Issue:5 Topics: Cluster Headache; Combined Modality Therapy; Dihydroergotamine; Ergotamine; Humans; Indoles; Lidocai	1992
Atypical cluster headache in a 72 year old responds to sumatriptan. Headache, 1992, Volume: 32, Issue:8 Topics: Aged; Cluster Headache; Humans; Indoles; Male; Sulfonamides; Sumatriptan; Vasoconstrictor Agents	1992
Serotonin receptors and headache. The New England journal of medicine, 1991, Aug-01, Volume: 325, Issue:5 Topics: Cluster Headache; Headache; Humans; Indoles; Migraine Disorders; Receptors, Serotonin; Sulfonamides;	1991
Methodology of clinical trials of sumatriptan in migraine and cluster headache. European neurology, 1991, Volume: 31, Issue:5 Topics: Cluster Headache; Double-Blind Method; Female; Humans; Indoles; Male; Migraine Disorders; Multicente	1991
[Sumatriptan in migraine and cluster headache]. Nederlands tijdschrift voor geneeskunde, 1991, Aug-31, Volume: 135, Issue:35 Topics: Cluster Headache; Contraindications; Humans; Indoles; Migraine Disorders; Sulfonamides; Sumatriptan;	1991

sumatriptan and Atypical Cluster Headache