Page last updated: 2024-11-04

sumatriptan and Apoplexy

sumatriptan has been researched along with Apoplexy in 7 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects."8.12Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022)
"A 23-year-old woman developed ischemic stroke (IS) 8 to 12 hours after ingestion of sumatriptan (ST) and then developed mucosal bleeding secondary to acute thrombocytopenia likely due to dipyridamole (DP) on the 10th day poststroke."4.87Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy. ( Adams, C; Ames, PR; Dhirendra, A, 2011)
" In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects."4.12Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022)
"Triptans, 5-HT1B/1D agonists used in migraine treatment, are rarely involved in serious coronary events due to vasospasm."2.41[Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause]. ( Hedenmalm, K, 2000)
"Triptans are widely used to treat migraine but have been associated with stroke, myocardial infarction (MI), and ischemic heart disease (IHD) in case reports."1.32Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice. ( Brown, MM; Hall, GC; MacRae, KD; Mo, J, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Shayan, M1
Eslami, F1
Amanlou, A1
Solaimanian, S1
Rahimi, N1
Rashidian, A1
Ejtemaei-Mehr, S1
Ghasemi, M1
Dehpour, AR1
Rothrock, JF1
Adams, C1
Dhirendra, A1
Ames, PR1
Petro, DJ1
Hall, GC1
Brown, MM1
Mo, J1
MacRae, KD1
Hedenmalm, K1

Reviews

2 reviews available for sumatriptan and Apoplexy

ArticleYear
Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2011, Volume: 17, Issue:1

    Topics: Acute Disease; Adult; Brain Ischemia; Dipyridamole; Female; Hemorrhage; Humans; Iatrogenic Disease;

2011
[Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause].
    Lakartidningen, 2000, Jun-21, Volume: 97, Issue:25

    Topics: Contraindications; Coronary Disease; Humans; Migraine Disorders; Myocardial Infarction; Risk Assessm

2000

Other Studies

5 other studies available for sumatriptan and Apoplexy

ArticleYear
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K
    Toxicology and applied pharmacology, 2022, 11-01, Volume: 454

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Mo

2022
Margaritas... not science.
    Headache, 2009, Volume: 49, Issue:6

    Topics: Biomedical Research; Causality; Cerebrovascular Circulation; Clinical Trials as Topic; Drug Design;

2009
Cerebral vasoconstriction and stroke after use of serotonergic drugs.
    Neurology, 2002, Aug-27, Volume: 59, Issue:4

    Topics: Antidepressive Agents; Brain; Cerebrovascular Circulation; Dietary Supplements; Drug and Narcotic Co

2002
Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice.
    Neurology, 2004, Feb-24, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Cardiovascular Diseases; Cause

2004
[Migraine has to be treated. Otherwise a stroke threatens].
    MMW Fortschritte der Medizin, 2002, Feb-14, Volume: 144, Issue:7

    Topics: Humans; Indoles; Migraine Disorders; Pyrrolidines; Risk Factors; Serotonin Receptor Agonists; Stroke

2002