Page last updated: 2024-11-04

sumatriptan and Anesthesia

sumatriptan has been researched along with Anesthesia in 11 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" Drug-drug interactions are further implicated through this study."1.29Cerebral blood flow effects of sumatriptan in drug combinations in the baboon model. ( Dormehl, IC; Hugo, N; Oliver, DW, 1995)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Létienne, R1
Verscheure, Y1
John, GW1
Dormehl, IC2
Oliver, DW2
Hugo, N2
Drieu la Rochelle, C1
O'Connor, SE1
Gupta, P2
Brown, D1
Butler, P2
Ellis, P1
Grayson, KL1
Land, GC1
Macor, JE1
Robson, SF1
Wythes, MJ1
Shepperson, NB2
De Vries, P2
Sánchez-López, A1
Centurión, D1
Heiligers, JP2
Saxena, PR3
Villalón, CM2
Willems, EW1
Trion, M1
McHarg, A1
Vayssettes-Courchay, C1
Ragonnet, C1
Cordi, AA1
Verbeuren, TJ1
Den Boer, MO1
Somers, JA1
Perren, MJ1
Feniuk, W1
Humphrey, PP1

Other Studies

11 other studies available for sumatriptan and Anesthesia

ArticleYear
Investigation of the effects of naratriptan, rizatriptan, and sumatriptan on jugular venous oxygen saturation in anesthetized pigs: implications for their mechanism of acute antimigraine action.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Anesthesia; Animals; Blood Gas Analysis; Hemodynamics; Indoles; Jugular Veins; Male; Migraine Disord

2003
Cerebral blood flow effects of sumatriptan in drug combinations in the baboon model.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:9

    Topics: Acetazolamide; Anesthesia; Anesthetics; Animals; Calcium; Calcium Channel Blockers; Cerebrovascular

1995
Effect of sumatriptan on cerebral blood flow in the baboon model.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:8

    Topics: Anesthesia; Animals; Cerebrovascular Circulation; Male; Papio; Sumatriptan; Tomography, Emission-Com

1994
Sumatriptan-induced saphenous venoconstriction in the anaesthetized dog through 5-HT1-like receptor activation.
    British journal of pharmacology, 1995, Volume: 116, Issue:4

    Topics: Anesthesia; Animals; Aorta, Thoracic; Brachial Artery; Dogs; Dose-Response Relationship, Drug; Femal

1995
The in vivo pharmacological profile of a 5-HT1 receptor agonist, CP-122,288, a selective inhibitor of neurogenic inflammation.
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Dogs; Dose-Res

1995
The canine external carotid vasoconstrictor 5-HT1 receptor: blockade by 5-HT1B (SB224289), but not by 5-HT1D (BRL15572) receptor antagonists.
    European journal of pharmacology, 1998, Nov-27, Volume: 362, Issue:1

    Topics: Anesthesia; Animals; Biphenyl Compounds; Blood Pressure; Carotid Artery, External; Dogs; Dose-Respon

1998
Pharmacological evidence that alpha1-and alpha2-adrenoceptors mediate vasoconstriction of carotid arteriovenous anastomoses in anaesthetized pigs.
    British journal of pharmacology, 1999, Volume: 127, Issue:5

    Topics: Anesthesia; Animals; Arteriovenous Anastomosis; Azepines; Carotid Arteries; Hemodynamics; Migraine D

1999
The in vivo pharmacological profile of eletriptan (UK-116,044): a potent and novel 5-HT(1B/1D) receptor agonist.
    European journal of pharmacology, 2000, Jun-09, Volume: 398, Issue:1

    Topics: Anesthesia; Animals; Blood Flow Velocity; Blood Proteins; Capillary Permeability; Coronary Circulati

2000
In vivo analysis of adrenergic and serotoninergic constrictions of the rabbit saphenous vein.
    European journal of pharmacology, 2000, Nov-24, Volume: 408, Issue:3

    Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Ben

2000
Comparative effects of the antimigraine drugs sumatriptan and ergotamine on the distribution of cardiac output in anaesthetized pigs.
    Cephalalgia : an international journal of headache, 1992, Volume: 12, Issue:4

    Topics: Anesthesia; Animals; Blood Flow Velocity; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Card

1992
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
    British journal of pharmacology, 1991, Volume: 102, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Gangl

1991