Page last updated: 2024-11-04

sumatriptan and Altitude Hypoxia

sumatriptan has been researched along with Altitude Hypoxia in 7 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Altitude Hypoxia: Low ambient oxygen tension associated with ALTITUDE.

Research Excerpts

ExcerptRelevanceReference
"To determine the impact of sumatriptan prophylaxis on acute mountain sickness (AMS) and altitude headache development within 24 hours of ascent, we designed a double-blind, randomized, clinical trial."5.12Sumatriptan for prevention of acute mountain sickness: randomized clinical trial. ( Gorouhi, F; Jafarian, S; Lotfi, J; Salimi, S, 2007)
"Acetazolamide was associated with a reduction in acute mountain sickness symptoms, with a number needed to treat ranging from 8 to 3 among 3 trials and at doses ranging from 250 to 750 mg daily."2.48Pharmacologic prophylaxis for acute mountain sickness: a systematic shortcut review. ( Emmett, TW; Malka, ST; Seupaul, RA; Welch, JL, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gonzalez Garay, A1
Molano Franco, D1
Nieto Estrada, VH1
Martí-Carvajal, AJ1
Arevalo-Rodriguez, I1
Mampreso, E1
Maggioni, F1
Viaro, F1
Disco, C1
Zanchin, G1
Seupaul, RA1
Welch, JL1
Malka, ST1
Emmett, TW1
Utiger, D1
Eichenberger, U1
Bernasch, D1
Baumgartner, RW2
Bärtsch, P2
Jafarian, S1
Gorouhi, F1
Salimi, S1
Lotfi, J1
Burtscher, M1
Likar, R1
Nachbauer, W1
Schaffert, W1
Philadelphy, M1
Maggi, S1
Kleger, GR1
Ballmer, PE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Randomized Double-Blind Control Trial Evaluating the Utility of Continuous Positive Airway Pressure (CPAP) in the Treatment of High Altitude Pulmonary Edema (HAPE)[NCT04186598]264 participants (Anticipated)Interventional2020-01-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for sumatriptan and Altitude Hypoxia

ArticleYear
Interventions for preventing high altitude illness: Part 2. Less commonly-used drugs.
    The Cochrane database of systematic reviews, 2018, 03-12, Volume: 3

    Topics: Acetazolamide; Altitude Sickness; Cathartics; Citric Acid; Diuretics; Humans; Organometallic Compoun

2018
Pharmacologic prophylaxis for acute mountain sickness: a systematic shortcut review.
    Annals of emergency medicine, 2012, Volume: 59, Issue:4

    Topics: Acetazolamide; Altitude Sickness; Amines; Carbonic Anhydrase Inhibitors; Cyclohexanecarboxylic Acids

2012

Trials

3 trials available for sumatriptan and Altitude Hypoxia

ArticleYear
Transient minor improvement of high altitude headache by sumatriptan.
    High altitude medicine & biology, 2002,Winter, Volume: 3, Issue:4

    Topics: Adult; Altitude Sickness; Chi-Square Distribution; Double-Blind Method; Female; Headache; Humans; Ma

2002
Sumatriptan for prevention of acute mountain sickness: randomized clinical trial.
    Annals of neurology, 2007, Volume: 62, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Altitude Sickness; Double-Blind Method; Drug Eruptions; Endpoint D

2007
Ibuprofen versus sumatriptan for high-altitude headache.
    Lancet (London, England), 1995, Jul-22, Volume: 346, Issue:8969

    Topics: Administration, Oral; Adult; Altitude Sickness; Cross-Over Studies; Double-Blind Method; Female; Hea

1995

Other Studies

2 other studies available for sumatriptan and Altitude Hypoxia

ArticleYear
Efficacy of oxygen inhalation in sumatriptan refractory "high altitude" cluster headache attacks.
    The journal of headache and pain, 2009, Volume: 10, Issue:6

    Topics: Adult; Altitude Sickness; Atmospheric Pressure; Calcium Channel Blockers; Cluster Headache; Drug Res

2009
Sumatriptan for high-altitude headache.
    Lancet (London, England), 1994, Nov-19, Volume: 344, Issue:8934

    Topics: Adult; Altitude Sickness; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Sumatript

1994