sumatriptan has been researched along with Alcohol Abuse in 3 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the possible influence of alcoholism on serotonergic control of growth hormone (GH) secretion, 6 mg of the 5-HT1D serotonergic receptor agonist, sumatriptan, was injected subcutaneously in a group of nine normal controls (aged 32 to 49 years) and in nine age-matched nondepressed male alcoholic subjects after 10 to 25 days of abstinence from alcohol." | 7.69 | Alcoholism abolishes the growth hormone response to sumatriptan administration in man. ( Coiro, V; Vescovi, PP, 1995) |
| "The general lack of efficacy of sumatriptan in producing alcohol-like symptoms or a desire to drink alcohol may suggest that the 5HT1D receptor plays little role in the pathophysiology of alcoholism." | 3.73 | Pharmacological challenge with a serotonin 1D agonist in alcohol dependence. ( Hugo, CJ; Maritz, JS; Pienaar, W; Stein, DJ; Vythilingum, B, 2005) |
| "To assess the possible influence of alcoholism on serotonergic control of growth hormone (GH) secretion, 6 mg of the 5-HT1D serotonergic receptor agonist, sumatriptan, was injected subcutaneously in a group of nine normal controls (aged 32 to 49 years) and in nine age-matched nondepressed male alcoholic subjects after 10 to 25 days of abstinence from alcohol." | 3.69 | Alcoholism abolishes the growth hormone response to sumatriptan administration in man. ( Coiro, V; Vescovi, PP, 1995) |
| "Some studies have associated alcohol dependence (AD) with the human serotonin (5-HT)(1B) receptor (HTR1B)." | 1.34 | Diplotypes of the human serotonin 1B receptor promoter predict growth hormone responses to sumatriptan in abstinent alcohol-dependent men. ( Berrettini, W; Dahl, JP; Hardie, TL; Moss, HB; Xu, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vythilingum, B | 1 |
| Hugo, CJ | 1 |
| Maritz, JS | 1 |
| Pienaar, W | 1 |
| Stein, DJ | 1 |
| Moss, HB | 1 |
| Hardie, TL | 1 |
| Dahl, JP | 1 |
| Berrettini, W | 1 |
| Xu, K | 1 |
| Coiro, V | 1 |
| Vescovi, PP | 1 |
3 other studies available for sumatriptan and Alcohol Abuse
| Article | Year |
|---|---|
Pharmacological challenge with a serotonin 1D agonist in alcohol dependence.
Topics: Alcohol Drinking; Alcoholism; Behavior, Addictive; Cross-Over Studies; Emotions; Female; Humans; Mal | 2005 |
Diplotypes of the human serotonin 1B receptor promoter predict growth hormone responses to sumatriptan in abstinent alcohol-dependent men.
Topics: Adult; Alcoholism; Chi-Square Distribution; Ethnicity; Genotype; Growth Hormone; Humans; Male; Polym | 2007 |
Alcoholism abolishes the growth hormone response to sumatriptan administration in man.
Topics: Adult; Alcoholism; Growth Hormone; Humans; Male; Middle Aged; Reference Values; Serotonin Receptor A | 1995 |