sulthiame has been researched along with Epilepsies, Partial in 8 studies
sulthiame: was heading 1964-94 (see under THIAZINES 1964-90); use THIAZINES to search SULTHIAME 1966-94
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Excerpt | Relevance | Reference |
|---|---|---|
| "16 children had typical benign partial epilepsy with rolandic spikes (BPERS), 5 children with atypical forms and 4 children with no clinical seizures but cognitive disturbances possibly related to the FSW." | 5.32 | Treatment with Sulthiame (Ospolot) in benign partial epilepsy of childhood and related syndromes: an open clinical and EEG study. ( Deonna, T; Engler, F; Maeder-Ingvar, M; Roulet, E, 2003) |
| "Sulthiame was added in doses ranging from 10 to 40 mg/kg/day." | 1.91 | Use of sulthiame as add-on therapy in children with non-self-limited focal epilepsies of childhood. ( Adi, J; Cachia, P; Caraballo, R; Chacón, S; Espeche, A; Fortini, S; Galichio, S; Gallo, A; Gamboni, B; Reyes, G; Semprino, M, 2023) |
| "Sulthiame was administered at the dose of 50-300 mg/day (4-14 mg/kg body weight) as add-on therapy in all except one patient." | 1.35 | [Sulthiame treatment for patients with intractable epilepsy]. ( Fujii, T; Kimura, N; Kumada, T; Mikuni, T; Miyajima, T, 2009) |
| "16 children had typical benign partial epilepsy with rolandic spikes (BPERS), 5 children with atypical forms and 4 children with no clinical seizures but cognitive disturbances possibly related to the FSW." | 1.32 | Treatment with Sulthiame (Ospolot) in benign partial epilepsy of childhood and related syndromes: an open clinical and EEG study. ( Deonna, T; Engler, F; Maeder-Ingvar, M; Roulet, E, 2003) |
| "Carbamazepine has no effect on the EEG, in epilepsies with atypical course (atypical benign partial epilepsy, Landau-Kleffner syndrome, epilepsy with continuous spikes and waves during slow sleep [CSWS]) carbamazepine usually has no effect either on the seizures or on the EEG, on the contrary, in some cases both may even get worse." | 1.29 | Treatment of "benign" partial epilepsies of childhood, including atypical forms. ( Gross-Selbeck, G, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Caraballo, R | 1 |
| Reyes, G | 1 |
| Semprino, M | 1 |
| Chacón, S | 1 |
| Galichio, S | 1 |
| Adi, J | 1 |
| Gallo, A | 1 |
| Gamboni, B | 1 |
| Cachia, P | 1 |
| Fortini, S | 1 |
| Espeche, A | 1 |
| Miyajima, T | 1 |
| Kumada, T | 1 |
| Kimura, N | 1 |
| Mikuni, T | 1 |
| Fujii, T | 1 |
| Engler, F | 1 |
| Maeder-Ingvar, M | 1 |
| Roulet, E | 1 |
| Deonna, T | 1 |
| Basnec, A | 1 |
| Skarpa, D | 1 |
| Barisić, N | 1 |
| Jurin, M | 1 |
| Mucić-Pucić, B | 1 |
| Wirrell, E | 1 |
| Ho, AW | 1 |
| Hamiwka, L | 1 |
| Lerman, P | 1 |
| Lerman-Sagie, T | 1 |
| Gross-Selbeck, G | 1 |
| Bourgeois, BF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-inferiority Prospective Randomized Trial of Acetazolamide Versus Diazepam in Patients With Continuous Spike and Wave in Sleep (CSWS)/Landau Kleffner Syndrome (LKS)[NCT02904265] | Phase 2/Phase 3 | 3 participants (Actual) | Interventional | 2016-09-30 | Terminated (stopped due to Lack of enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Expect improved side effect profile of acetazolamide compared to diazepam at short-term follow up (NCT02904265)
Timeframe: 4-8 weeks of start of medications
| Intervention | Participants (Count of Participants) |
|---|---|
| Diazepam | 1 |
| Acetazolamide | 2 |
1 review available for sulthiame and Epilepsies, Partial
| Article | Year |
|---|---|
Drug treatment of benign focal epilepsies of childhood.
Topics: Acetates; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dru | 2000 |
1 trial available for sulthiame and Epilepsies, Partial
| Article | Year |
|---|---|
[The risk of second seizure in children with benign childhood epilepsy with centrotemporal spikes without treatment--a prospective study].
Topics: Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Humans; Recurrence; Thiazines | 2005 |
6 other studies available for sulthiame and Epilepsies, Partial
| Article | Year |
|---|---|
Use of sulthiame as add-on therapy in children with non-self-limited focal epilepsies of childhood.
Topics: Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, Partial; Humans; Retrospe | 2023 |
[Sulthiame treatment for patients with intractable epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Disabled Children; Epilepsies, Partial; | 2009 |
Treatment with Sulthiame (Ospolot) in benign partial epilepsy of childhood and related syndromes: an open clinical and EEG study.
Topics: Adolescent; Child; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Humans; M | 2003 |
Sulthiame therapy for continuous spike and wave in slow-wave sleep.
Topics: Child, Preschool; Electroencephalography; Epilepsies, Partial; Humans; Male; Sleep; Thiazines | 2006 |
Sulthiame revisited.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Huma | 1995 |
Treatment of "benign" partial epilepsies of childhood, including atypical forms.
Topics: Adrenocorticotropic Hormone; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinone | 1995 |