sultamicillin and Heart-Arrest

Topics: Ampicillin; Animals; Animals, Domestic; Anti-Bacterial Agents; Bites and Stings; Cats; Child Abuse; Dogs; Emergency Service, Hospital; Fatal Outcome; Female; Heart Arrest; Hemorrhage; Humans; Infant; Japan; Male; Pets; Risk Factors; Sulbactam; Treatment Outcome

The risk of central line associated blood stream infections (CLABSI) related to cooling catheters used for therapeutic hypothermia (TH) is unclear.. We performed a retrospective analysis on 131 cardiac arrest survivors between 2007 and 2010, who underwent TH by femorally placed endovascular cooling catheter. All patients received prophylactic intravenous ampicillin-sulbactam for 72 hours to reduce the risk of aspiration pneumonia. Cooling catheter related CLABSI and other infections over a period of seven days from initiation of TH were estimated.. Of a total 131 patients, 16 (12%) patients had bacteremia or infection prior to initiation of TH and were excluded. Of the remaining 115 (88%) patients, zero (0%) patients had cooling catheter related CLABSI and 23 (20%) patients had other infections during the study period.. In cardiac arrest survivors undergoing TH, femorally placed endovascular cooling catheter is not associated with an increased incidence of CLABSI.

Topics: Aged; Ampicillin; Anti-Bacterial Agents; Catheter-Related Infections; Catheterization, Central Venous; Cross Infection; Endovascular Procedures; Female; Heart Arrest; Humans; Hypothermia, Induced; Male; Middle Aged; Retrospective Studies; Sepsis; Sulbactam