sultamicillin and Autoimmune-Diseases

sultamicillin has been researched along with Autoimmune-Diseases* in 1 studies

Other Studies

1 other study(ies) available for sultamicillin and Autoimmune-Diseases

ArticleYear
Localized linear IgA disease induced by ampicillin/sulbactam.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:1

    We describe a patient who developed an exclusively perianal-intergluteal vesicular eruption after receiving a course of ampicillin/sulbactam. Direct immunofluorescence microscopy of perilesional skin demonstrated linear deposits of IgA along the dermal-epidermal junction. Circulating IgA autoantibodies against the 120-kd soluble ectodomain of bullous pemphigoid antigen 180 (LAD-1 autoantigen) were detected by immunoblotting. Discontinuation of the antibiotics resulted in a rapid resolution of the skin lesions. This is a most unusual case of localized drug-induced linear IgA disease.

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Autoantibodies; Autoantigens; Autoimmune Diseases; Biopsy; Carrier Proteins; Collagen Type XVII; Cytoskeletal Proteins; Drug Eruptions; Dystonin; Humans; Immunoglobulin A; Male; Nerve Tissue Proteins; Non-Fibrillar Collagens; Skin; Skin Diseases, Vesiculobullous; Sulbactam

2004