Page last updated: 2024-11-04

sulpiride and Vomiting

sulpiride has been researched along with Vomiting in 18 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
" She developed these symptoms after having been administered parenteral levosulpiride to control vomiting due to secondary adrenal insufficiency."7.88Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis. ( Biswas, A; Desai, D; Gupta, K; Kumar, R, 2018)
"The antiemetic activity, gastric motor activity, and dopamine receptor effects of metoclopramide, dazopride, and sulpiride were assessed to establish if enhancement of gastric motility or antagonism of central dopamine receptors is the predominant action for drug-induced suppression of cisplatin-induced emesis."7.67Antagonism of cisplatin-induced emesis by metoclopramide and dazopride through enhancement of gastric motility. ( Alphin, RS; Dannenburg, WN; Johnson, DN; Kinnier, WJ; Leonard, CA; Proakis, AG; Sancilio, LF; Smith, WL; Ward, JW, 1986)
" We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy."7.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
" Both these doses have been effective in reducing the episodes of vomiting other than in preventing nausea and retching if considered versus controls and also versus droperidol at the doses of 5 mg (50 mg L-sul = 12%, 100 mg = 4%, droperidol = 20%, controls = 28%)."5.06[Antiemetic effect of the levo isomer of sulpiride (L-sulpiride) in humans]. ( Florio, T; Forgione, A; Lombardi, G; Mastronardi, P; Mazzarella, B; Merola, B; Pinto, M; Savastano, S; Scanni, E; Schettini, G, 1989)
" She developed these symptoms after having been administered parenteral levosulpiride to control vomiting due to secondary adrenal insufficiency."3.88Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis. ( Biswas, A; Desai, D; Gupta, K; Kumar, R, 2018)
"The value of administering 25 mg of levosulpiride per os approximately one hour before the sodium fluorescein bolus used in fluorangiography is assessed in order to avoid to the onset of nausea and/or vomiting during and after the test."3.68[The clinical use of levosulpiride in retinal fluorangiography]. ( Bianchetti, L; Fusi, L; Paneghel, D; Rosina, A; Torrero, M; Vanzetti, M, 1990)
"The antiemetic activity, gastric motor activity, and dopamine receptor effects of metoclopramide, dazopride, and sulpiride were assessed to establish if enhancement of gastric motility or antagonism of central dopamine receptors is the predominant action for drug-induced suppression of cisplatin-induced emesis."3.67Antagonism of cisplatin-induced emesis by metoclopramide and dazopride through enhancement of gastric motility. ( Alphin, RS; Dannenburg, WN; Johnson, DN; Kinnier, WJ; Leonard, CA; Proakis, AG; Sancilio, LF; Smith, WL; Ward, JW, 1986)
" We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy."3.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"A new benzamide, cis-N-(1-benzyl-2-methylpyrrolidin - 3 - yl) - 5 - chloro - 2 - methoxy - 4 - methylaminobenzamide (YM-09151-2) exhibited more potent and longer-lasting inhibitory effects on apomorphine-induced behaviours (stereotyped behaviour, emesis and hypothermia), and methamphetamine-induced stereotyped behaviour, conditioned avoidance response and open field behaviour, conditioned avoidance response and open field behaviour than either structurally similar benzamides (YM-0850 and sulpiride) or classical neuroleptics [chlorpromazine (CPZ) and haloperidol(HPD)]."3.66Neuroleptic properties of cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide (YM-09151-2) with selective antidopaminergic activity. ( Maeno, H; Nishikori, K; Noshiro, O; Usuda, S, 1981)
"The effect against nausea is of particular interest."2.87Amisulpride in the prevention of nausea and vomiting induced by cisplatin-based chemotherapy: a dose-escalation study. ( Christensen, TB; Daugaard, G; Fox, GM; Herrstedt, J; Holmskov, K; Molassiotis, A; Summers, Y; Taylor, PD, 2018)
"Levo-sulpiride is a substituted benzamide with antiemetic activity 3-8 times more potent than the racemic form and the d-isomer."2.38[Antiemetic properties of levo-sulpiride]. ( Guslandi, M, 1990)
" Thus, the inhibitory dose-response effects of a D2-preferring [sulpride], a D3-preferring [U 99194A] and combination of varying doses of these antagonists [sulpride + U 99194A] were evaluated on the ability of the cited agonists to produce vomiting."1.30The role of D2 and D3 dopamine receptors in the mediation of emesis in Cryptotis parva (the least shrew). ( Ahmad, B; Darmani, NA; Zhao, W, 1999)
"Severe vomiting was evoked by Apo in dogs, but not by Eph even when lethal dose (20 mg."1.28[Comparison of central stimulating effects between ephedrine and apomorphine]. ( Li, BH; Li, Q, 1991)
"Remoxipride was shown to be a selective dopamine D2 receptor antagonist since it displaced [3H]spiperone (IC50 = 1570 nM) but not [3H]flupentixol (IC50 greater than 100 000 nM) in rat striatum, and did not inhibit striatal DA-sensitive adenylate cyclase in vitro (IC50 greater than 100 000 nM)."1.27Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain. ( Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO, 1984)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's5 (27.78)18.2507
2000's1 (5.56)29.6817
2010's2 (11.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Yan, XJ1
Xu, P1
Qiu, HY1
Wang, B1
Luo, QQ1
Chen, SL1
Herrstedt, J1
Summers, Y1
Daugaard, G1
Christensen, TB1
Holmskov, K1
Taylor, PD1
Fox, GM1
Molassiotis, A1
Desai, D1
Gupta, K1
Kumar, R1
Biswas, A1
Henry, A1
Charpiat, B1
Vial, T1
Franchini, S1
Cuilleret, FJ1
Milon, H1
Usuda, S1
Nishikori, K1
Noshiro, O1
Maeno, H1
Ogren, SO1
Hall, H1
Köhler, C1
Magnusson, O1
Lindbom, LO1
Angeby, K1
Florvall, L1
Cohen, N1
Alon, I1
Almoznino-Sarfian, D1
Gorelik, O1
Chachasvili, S1
Litvinjuk, V1
Modai, D1
Weissgarten, J1
Darmani, NA1
Zhao, W1
Ahmad, B1
Corsini, GU1
Zompo, MD1
Cianchetti, C1
Mangoni, A1
Li, Q1
Li, BH1
Torrero, M1
Rosina, A1
Paneghel, D1
Bianchetti, L1
Fusi, L1
Vanzetti, M1
Guslandi, M1
Schettini, G1
Mastronardi, P1
Scanni, E1
Pinto, M1
Forgione, A1
Florio, T1
Savastano, S1
Merola, B1
Lombardi, G1
Mazzarella, B1
Bianconcini, G1
Mazzali, F1
Morini, A1
Gobbi, F1
Rosenblatt, E1
Lev, LM1
Robinson, E1
Alphin, RS1
Proakis, AG1
Leonard, CA1
Smith, WL1
Dannenburg, WN1
Kinnier, WJ1
Johnson, DN1
Sancilio, LF1
Ward, JW1
Sakata, Y1
Suzuki, H1
Satoh, T1
Kawatsu, S1
Tanabe, K1
Okamoto, K1
Takagi, S1
Komatsu, Y1
Kawakami, K1
Yoshida, Y1
Decio, B1
Libutti, M1
Allaria, B1
Picozzi, G1

Reviews

1 review available for sulpiride and Vomiting

ArticleYear
[Antiemetic properties of levo-sulpiride].
    Minerva medica, 1990, Volume: 81, Issue:12

    Topics: Chemical Phenomena; Chemistry; Gastrointestinal Diseases; Humans; Nausea; Postoperative Complication

1990

Trials

5 trials available for sulpiride and Vomiting

ArticleYear
Antiemetics improve the tolerance of polyethylene glycol for colonoscopy preparation: A randomized clinical trial.
    Medicine, 2021, Mar-12, Volume: 100, Issue:10

    Topics: Adult; Aged; Antiemetics; Cathartics; Colon; Colonoscopy; Domperidone; Female; Humans; Incidence; In

2021
Amisulpride in the prevention of nausea and vomiting induced by cisplatin-based chemotherapy: a dose-escalation study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018, Volume: 26, Issue:1

    Topics: Adult; Aged; Amisulpride; Antiemetics; Cisplatin; Dopamine Antagonists; Female; Humans; Male; Middle

2018
Sulpiride versus metoclopramide in nononcologic patients with vomiting or nausea.
    Journal of clinical gastroenterology, 1999, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Dose-Response Relationship, Drug; Double-Bl

1999
[Antiemetic effect of the levo isomer of sulpiride (L-sulpiride) in humans].
    Minerva anestesiologica, 1989, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Droperidol; Drug Administration Schedule; Femal

1989
High-dose dexamethasone and high-dose metoclopramide versus high-dose dexamethasone and sulpiride in the management of cisplatin-induced emesis.
    Oncology, 1988, Volume: 45, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dexamethasone;

1988

Other Studies

12 other studies available for sulpiride and Vomiting

ArticleYear
Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis.
    BMJ case reports, 2018, Aug-11, Volume: 2018

    Topics: Adrenal Insufficiency; Antiemetics; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans;

2018
Pheochromocytoma unmasked by amisulpride and tiapride.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:5

    Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Channel Blockers; Headache; Humans; Hypertension;

2005
Neuroleptic properties of cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide (YM-09151-2) with selective antidopaminergic activity.
    Psychopharmacology, 1981, Volume: 73, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Chlorpropamide; Dogs; Drug Evaluation, Precl

1981
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding

1984
The role of D2 and D3 dopamine receptors in the mediation of emesis in Cryptotis parva (the least shrew).
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:11-12

    Topics: Analysis of Variance; Animals; Apomorphine; Benzopyrans; Brain Chemistry; Disease Models, Animal; Do

1999
Therapeutical efficacy of a combination of apomorphine with sulpiride or metoclopramide in Parkinsonism.
    Psychopharmacologia, 1976, May-28, Volume: 47, Issue:2

    Topics: Adult; Apomorphine; Drug Therapy, Combination; Haloperidol; Humans; Male; Metoclopramide; Parkinson

1976
[Comparison of central stimulating effects between ephedrine and apomorphine].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Animals; Apomorphine; Blepharoptosis; Catalepsy; Ephedrine; Haloperidol; Male; Mice; Motor Activity;

1991
[The clinical use of levosulpiride in retinal fluorangiography].
    Minerva anestesiologica, 1990, Volume: 56, Issue:12

    Topics: Adult; Aged; Fluorescein; Fluorescein Angiography; Fluoresceins; Humans; Middle Aged; Nausea; Radiog

1990
[Antiemetic protocol in oncohematologic polychemotherapy].
    Minerva medica, 1988, Volume: 79, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Chlorph

1988
Antagonism of cisplatin-induced emesis by metoclopramide and dazopride through enhancement of gastric motility.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:5

    Topics: Animals; Benzamides; Cisplatin; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Mot

1986
[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluation; Female; H

1986
[Prevention of postoperative vomiting with sulpiride].
    Atti della Accademia medica lombarda, 1973, Volume: 28, Issue:1-4

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Postoperative Complications; Sulpiride;

1973