sulpiride has been researched along with Tourette Syndrome in 15 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The Patient had started visiting a new neurologist three weeks before admission and received Sulpiride against Tourette syndrome (TS) in a rapid escalation manner over a short period." | 8.12 | [Sulpiride induced dystonia in a patient with Tourette syndrome. A stroke-mimicking presentation]. ( Abdelnaby, R; Abosrea, MA; Elsayed, M; Rudek, MA; Schönfeldt-Lecuona, C, 2022) |
| "Pharmaceutical development was adopted in the current study to propose a pediatric rectal formulation of sulpiride as a substitute to the available oral or parenteral formulations in the management of Tourette syndrome (TS)." | 7.81 | Pediatric suppositories of sulpiride solid dispersion for treatment of Tourette syndrome: in vitro and in vivo investigations. ( Emam, SE; Ghazy, FE; Shehata, TM; Zidan, AS, 2015) |
| "A 14-year-old boy with obsessive-compulsive disorder (OCD) developed, under fluvoxamine treatment, acute symptoms of Tourette's syndrome (TS) with aggravation of the OCD." | 7.69 | Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder. ( Fennig, S; Fennig, SN; Pato, M; Weitzman, A, 1994) |
| "Sulpiride is a selective dopamine D2 antagonist." | 5.35 | Short-term sulpiride treatment of children and adolescents with Tourette syndrome or chronic tic disorder. ( Chen, HJ; Chiu, NC; Ho, CS; Lue, HC; Shen, EY, 2009) |
| "One hundred and fourteen patients with Gilles de la Tourette syndrome have been reviewed." | 5.28 | Management of Gilles de la Tourette syndrome using sulpiride. ( Lees, AJ; Robertson, MM; Schnieden, V, 1990) |
| " The Patient had started visiting a new neurologist three weeks before admission and received Sulpiride against Tourette syndrome (TS) in a rapid escalation manner over a short period." | 4.12 | [Sulpiride induced dystonia in a patient with Tourette syndrome. A stroke-mimicking presentation]. ( Abdelnaby, R; Abosrea, MA; Elsayed, M; Rudek, MA; Schönfeldt-Lecuona, C, 2022) |
| "Pharmaceutical development was adopted in the current study to propose a pediatric rectal formulation of sulpiride as a substitute to the available oral or parenteral formulations in the management of Tourette syndrome (TS)." | 3.81 | Pediatric suppositories of sulpiride solid dispersion for treatment of Tourette syndrome: in vitro and in vivo investigations. ( Emam, SE; Ghazy, FE; Shehata, TM; Zidan, AS, 2015) |
| "Following ten years of continuous olanzapine therapy a 51 years old man developed a Gilles de la Tourette syndrome which disappeared after changing to amisulprid." | 3.74 | [Gilles-de-la-Tourette Syndrome as a Tardive Dyskinesia]. ( Friederich, M; Kozian, R, 2007) |
| "A 14-year-old boy with obsessive-compulsive disorder (OCD) developed, under fluvoxamine treatment, acute symptoms of Tourette's syndrome (TS) with aggravation of the OCD." | 3.69 | Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder. ( Fennig, S; Fennig, SN; Pato, M; Weitzman, A, 1994) |
| "The treatment of Tourette's syndrome is a challenge." | 2.44 | [The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome]. ( Müller-Vahl, KR, 2007) |
| "Tardive Tourette syndrome is an extrapyramidal symptom which appears after long-term neuroleptic use." | 2.43 | [Two cases of tardive Tourette syndrome]. ( Ohmori, T; Yamauchi, K, 2006) |
| "We reviewed articles in English dealing with research into the effect of atypical antipsychotic drugs on tic reduction in Tourette's syndrome." | 2.41 | [Treatment of tics in Tourette syndrome with atypical antipsychotic drugs]. ( Jørgensen, JI; Sindø, I, 2002) |
| "The treatment of the Gilles de la Tourette syndrome has evolved from case reports, clinical experience and more recently blinded trials usually in small numbers of patients." | 2.41 | Gilles de la Tourette syndrome: symptomatic treatment based on evidence. ( Robertson, MM; Stern, JS, 2000) |
| "Sulpiride is a selective dopamine D2 antagonist." | 1.35 | Short-term sulpiride treatment of children and adolescents with Tourette syndrome or chronic tic disorder. ( Chen, HJ; Chiu, NC; Ho, CS; Lue, HC; Shen, EY, 2009) |
| "Patients with Tourette's syndrome often develop multiple psychopathological symptoms beyond the basic symptoms (motor and vocal tics)." | 1.31 | [Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear]. ( Barnett, W; Bednarz, K; Haisch, S, 2002) |
| "One hundred and fourteen patients with Gilles de la Tourette syndrome have been reviewed." | 1.28 | Management of Gilles de la Tourette syndrome using sulpiride. ( Lees, AJ; Robertson, MM; Schnieden, V, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abdelnaby, R | 1 |
| Abosrea, MA | 1 |
| Schönfeldt-Lecuona, C | 1 |
| Rudek, MA | 1 |
| Elsayed, M | 1 |
| Zidan, AS | 1 |
| Emam, SE | 1 |
| Shehata, TM | 1 |
| Ghazy, FE | 1 |
| Ho, CS | 1 |
| Chen, HJ | 1 |
| Chiu, NC | 1 |
| Shen, EY | 1 |
| Lue, HC | 1 |
| Rickards, H | 1 |
| Cavanna, AE | 1 |
| Worrall, R | 1 |
| Bednarz, K | 1 |
| Haisch, S | 1 |
| Barnett, W | 1 |
| Sindø, I | 1 |
| Jørgensen, JI | 1 |
| Fountoulakis, KN | 1 |
| Iacovides, A | 1 |
| St Kaprinis, G | 1 |
| Dehning, S | 1 |
| Riedel, M | 1 |
| Müller, N | 1 |
| Yamauchi, K | 1 |
| Ohmori, T | 1 |
| Müller-Vahl, KR | 1 |
| Kozian, R | 1 |
| Friederich, M | 1 |
| Fennig, S | 1 |
| Fennig, SN | 1 |
| Pato, M | 1 |
| Weitzman, A | 1 |
| Robertson, MM | 2 |
| Stern, JS | 1 |
| Trillet, M | 1 |
| Moreau, T | 1 |
| Daléry, J | 1 |
| de Villard, R | 1 |
| Aimard, G | 1 |
| Schnieden, V | 1 |
| Lees, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Behavioral Therapy for Children and Adolescents With Tourette Syndrome: A Randomized Controlled Trial in Taiwan[NCT03621059] | 46 participants (Actual) | Interventional | 2015-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for sulpiride and Tourette Syndrome
| Article | Year |
|---|---|
[Treatment of tics in Tourette syndrome with atypical antipsychotic drugs].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine Antagonists; Humans; Olanzapine; Pirenzep | 2002 |
[Two cases of tardive Tourette syndrome].
Topics: Adult; Akathisia, Drug-Induced; Alcoholism; Amantadine; Antipsychotic Agents; Cholinergic Antagonist | 2006 |
[The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome].
Topics: Amisulpride; Anti-Dyskinesia Agents; Benzamides; Dopamine Antagonists; Germany; Humans; Practice Gui | 2007 |
Gilles de la Tourette syndrome: symptomatic treatment based on evidence.
Topics: Adolescent; Antidepressive Agents; Antipsychotic Agents; Behavior Therapy; Child; Child, Preschool; | 2000 |
11 other studies available for sulpiride and Tourette Syndrome
| Article | Year |
|---|---|
[Sulpiride induced dystonia in a patient with Tourette syndrome. A stroke-mimicking presentation].
Topics: Adult; Dystonia; Humans; Male; Stroke; Sulpiride; Tic Disorders; Tourette Syndrome; Young Adult | 2022 |
Pediatric suppositories of sulpiride solid dispersion for treatment of Tourette syndrome: in vitro and in vivo investigations.
Topics: Animals; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Mal | 2015 |
Short-term sulpiride treatment of children and adolescents with Tourette syndrome or chronic tic disorder.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Dopamine Antagonists; Dose-Response Relationsh | 2009 |
Treatment practices in Tourette syndrome: the European perspective.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Atomoxetine Hydrochloride | 2012 |
[Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear].
Topics: Adult; Anxiety Disorders; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Combined Modality | 2002 |
Successful treatment of Tourette's disorder with amisulpride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Female; Humans; Sulpiride; Tourette Syndrome | 2004 |
Aripiprazole in a patient vulnerable to side effects.
Topics: Adult; Amenorrhea; Amisulpride; Antipsychotic Agents; Aripiprazole; Female; Galactorrhea; Humans; Pi | 2005 |
[Gilles-de-la-Tourette Syndrome as a Tardive Dyskinesia].
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Dyskinesia, Drug-Indu | 2007 |
Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder.
Topics: Adolescent; Arousal; Drug Therapy, Combination; Fluvoxamine; Humans; Loxapine; Male; Neurologic Exam | 1994 |
[Treatment of Gilles de la Tourette's disease with amisulpride].
Topics: Adolescent; Amisulpride; Antipsychotic Agents; Child; Child, Preschool; Female; Humans; Male; Sulpir | 1990 |
Management of Gilles de la Tourette syndrome using sulpiride.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Retrospective Studies; Sleep Stag | 1990 |