Page last updated: 2024-11-04

sulpiride and Torsade de Pointes

sulpiride has been researched along with Torsade de Pointes in 15 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Research Excerpts

ExcerptRelevanceReference
"Sulpiride-induced torsades de pointes is rare."5.35Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning. ( Chang, JH; Fang, CC; Weng, TI, 2009)
"There was 1 case of torsade de pointes in a thioridazine overdose."1.42Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram. ( Berling, I; Isbister, GK, 2015)
"As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US FDA Adverse Event Reporting System (FAERS) database to detect signals of torsadogenicity for antipsychotics (APs)."1.39Antipsychotics and torsadogenic risk: signals emerging from the US FDA Adverse Event Reporting System database. ( Behr, ER; De Ponti, F; Koci, A; Moretti, U; Poluzzi, E; Raschi, E; Spina, E; Sturkenboom, M, 2013)
"Sulpiride-induced torsades de pointes is rare."1.35Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning. ( Chang, JH; Fang, CC; Weng, TI, 2009)
"Although clinical trials of the antipsychotic amisulpride revealed no cardiac adverse effects, four patients with severe cardiac toxicity after overdose were reported to Australian poisons information centres in 2004-2005."1.33Amisulpride deliberate self-poisoning causing severe cardiac toxicity including QT prolongation and torsades de pointes. ( Daly, F; Gosselin, S; Hackett, LP; Haider, T; Isbister, GK; John, S; Murray, L; O'Mullane, P, 2006)
"Torsades de pointes were treated with potassium chloride infusion and pace maker stimulation."1.28[Torsades de pointes during sultopride poisoning]. ( Aymes, C; Delille, F; Harry, P; Hass, C; Montaz, L; Simonin, D; Turcant, A; Varache, N, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's6 (40.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poluzzi, E1
Raschi, E1
Koci, A1
Moretti, U1
Spina, E1
Behr, ER1
Sturkenboom, M1
De Ponti, F1
Berling, I1
Isbister, GK4
Chung, AK1
Chua, SE1
Chang, JH1
Weng, TI1
Fang, CC1
Balit, CR1
Macleod, D1
Duffull, SB2
Joy, JP1
Coulter, CV1
Teng, PR1
Shen, TY1
Lai, TJ1
Sugiyama, A2
Satoh, Y1
Shiina, H1
Takeda, S1
Hashimoto, K1
Murray, L1
John, S1
Hackett, LP1
Haider, T1
O'Mullane, P1
Gosselin, S1
Daly, F1
Huang, BH1
Hsia, CP1
Chen, CY1
Kondou, N1
Hiasa, Y1
Kishi, K1
Fujinaga, H1
Ohishi, Y1
Ohtani, R1
Wada, T1
Aihara, T1
Züchner, H1
Lande, G1
Drouin, E1
Gauthier, C1
Chevallier, JC1
Godin, JF1
Chiffoleau, A1
Le Marec, H1
Montaz, L1
Varache, N1
Harry, P1
Aymes, C1
Turcant, A1
Delille, F1
Simonin, D1
Hass, C1

Reviews

1 review available for sulpiride and Torsade de Pointes

ArticleYear
[Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2003, Volume: 121, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Antitubercular Agents; Cat

2003

Other Studies

14 other studies available for sulpiride and Torsade de Pointes

ArticleYear
Antipsychotics and torsadogenic risk: signals emerging from the US FDA Adverse Event Reporting System database.
    Drug safety, 2013, Volume: 36, Issue:6

    Topics: Adverse Drug Reaction Reporting Systems; Amisulpride; Antipsychotic Agents; Arrhythmias, Cardiac; Be

2013
Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram.
    Annals of emergency medicine, 2015, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Drug Overdose; Electrocardiography; Fema

2015
Torsade de pointes associated with low-dose amisulpride: a case report.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:3

    Topics: Amisulpride; Antipsychotic Agents; Female; Humans; Middle Aged; Sulpiride; Torsades de Pointes

2010
Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:8

    Topics: Dopamine Antagonists; Female; Humans; Lidocaine; Long QT Syndrome; Magnesium Sulfate; Sulpiride; Tor

2009
Amisulpride overdose is frequently associated with QT prolongation and torsades de pointes.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:4

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bradycardia; Cohort Studies; Drug Overdose; Electrocardiog

2010
Prediction of torsade de pointes from the QT interval: analysis of a case series of amisulpride overdoses.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:2

    Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Overdos

2011
Sulpiride-associated torsade de pointes in a woman with bipolar disorder.
    Psychiatry and clinical neurosciences, 2012, Volume: 66, Issue:3

    Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Electrocardiogr

2012
Torsadegenic action of the antipsychotic drug sulpiride assessed using in vivo canine models.
    Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:2

    Topics: Action Potentials; Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Dogs; Dopamine Antagonist

2002
Amisulpride deliberate self-poisoning causing severe cardiac toxicity including QT prolongation and torsades de pointes.
    The Medical journal of Australia, 2006, Apr-03, Volume: 184, Issue:7

    Topics: Adult; Amisulpride; Antipsychotic Agents; Arrhythmias, Cardiac; Drug Overdose; Electrocardiography;

2006
Sulpiride induced torsade de pointes.
    International journal of cardiology, 2007, Jun-12, Volume: 118, Issue:3

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Coronary Angiography; Dose-Response Relationship, Drug

2007
[A case of life-threatening ventricular arrhythmias probably due to psychotropic drugs].
    Kokyu to junkan. Respiration & circulation, 1993, Volume: 41, Issue:11

    Topics: Electrocardiography, Ambulatory; Humans; Male; Middle Aged; Promethazine; Sulpiride; Tachycardia, Ve

1993
[QT prolongation and torsade de pointes--tachycardia in therapy with maprotiline].
    Deutsche medizinische Wochenschrift (1946), 2002, May-03, Volume: 127, Issue:18

    Topics: Amisulpride; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain Damage, Chronic;

2002
[Arrhythmogenic effects of sultopride chlorhydrate: clinical and cellular electrophysiological correlation].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:6

    Topics: Action Potentials; Amisulpride; Animals; Antipsychotic Agents; Electrocardiography; Female; Humans;

1992
[Torsades de pointes during sultopride poisoning].
    Journal de toxicologie clinique et experimentale, 1992, Volume: 12, Issue:8

    Topics: Adult; Amisulpride; Antipsychotic Agents; Humans; Male; Potassium Chloride; Sulpiride; Torsades de P

1992