sulpiride has been researched along with Stomach Ulcer in 21 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Highly significant differences in favour of Sulpiride were shown in both gastric and duodenal ulcer cases, maximum from the 20th day than less significative radiological results appeared." | 9.04 | [Sulpiride in the management of gastroduodenal ulcers. A comparative double-blind study]. ( Molle, M, 1975) |
| " In the present study, an attempt has been made to identify the effects of dopamine in stress-induced gastric ulcers, and concurrent alterations in various ulcer-influencing factors such as plasma corticosterone levels, gastric mucosal PGE(2) content and proton pump activity." | 7.76 | Differential response of A 68930 and sulpiride in stress-induced gastric ulcers in rats. ( Ahmad, A; Banu, N; Lohani, M; Mishra, V; Palit, G; Rasheed, N; Sharma, S; Singh, N; Singh, P, 2010) |
| "Highly significant differences in favour of Sulpiride were shown in both gastric and duodenal ulcer cases, maximum from the 20th day than less significative radiological results appeared." | 5.04 | [Sulpiride in the management of gastroduodenal ulcers. A comparative double-blind study]. ( Molle, M, 1975) |
| " In the present study, an attempt has been made to identify the effects of dopamine in stress-induced gastric ulcers, and concurrent alterations in various ulcer-influencing factors such as plasma corticosterone levels, gastric mucosal PGE(2) content and proton pump activity." | 3.76 | Differential response of A 68930 and sulpiride in stress-induced gastric ulcers in rats. ( Ahmad, A; Banu, N; Lohani, M; Mishra, V; Palit, G; Rasheed, N; Sharma, S; Singh, N; Singh, P, 2010) |
| "A single dose of the dopamine agonists L-dopa, bromocriptine or apomorphine produced a protective effect by significantly shortening of the length of stomach ulcerations." | 3.67 | The role of dopamine in the formation of gastric ulcers in rats. ( Aleksić, J; Geber, J; Gjuris, V; Ivanović, D; Marović, A; Reić, P; Sikirić, P; Suchanek, E, 1985) |
| "Risperidone pretreatment reverses the stress induced alteration in hexosamine, PGE(2) and microvascular permeability." | 1.37 | Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions. ( Krishnamurthy, S; Saxena, B; Singh, S, 2011) |
| "Treatment with sulpiride (10-320 mg/kg, p." | 1.29 | Sulpiride specifically attenuates psychological stress-induced gastric lesions in rodents. ( Kuratani, K; Maeda, N; Nomura, K; Yamaguchi, I, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (47.62) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nishimori, I | 2 |
| Minakuchi, T | 2 |
| Morimoto, K | 1 |
| Sano, S | 1 |
| Onishi, S | 2 |
| Takeuchi, H | 2 |
| Vullo, D | 2 |
| Scozzafava, A | 2 |
| Supuran, CT | 2 |
| Kohsaki, T | 1 |
| Rasheed, N | 1 |
| Ahmad, A | 1 |
| Singh, N | 1 |
| Singh, P | 1 |
| Mishra, V | 1 |
| Banu, N | 1 |
| Lohani, M | 1 |
| Sharma, S | 1 |
| Palit, G | 1 |
| Saxena, B | 1 |
| Krishnamurthy, S | 1 |
| Singh, S | 1 |
| Belova, EV | 1 |
| Groĭsman, SD | 1 |
| Karevina, TG | 1 |
| Khokholia, VP | 1 |
| Nomura, K | 1 |
| Maeda, N | 1 |
| Kuratani, K | 1 |
| Yamaguchi, I | 1 |
| Desai, JK | 1 |
| Parmar, NS | 1 |
| Puri, S | 1 |
| Ray, A | 1 |
| Chakravarti, AK | 1 |
| Sen, PA | 1 |
| Grabarević, Z | 1 |
| Rotkvić, I | 1 |
| Sikirić, P | 2 |
| Seiwerth, S | 1 |
| Dzaja, P | 1 |
| Perić, J | 1 |
| Kos, J | 1 |
| Ohmoto, K | 1 |
| Yamamoto, S | 1 |
| Hirokawa, M | 1 |
| Benelli, A | 1 |
| Poggioli, R | 1 |
| Cavazzuti, E | 1 |
| Arletti, R | 1 |
| Bertolini, A | 1 |
| Vergoni, AV | 1 |
| Nagamachi, Y | 1 |
| Chevrel, B | 1 |
| Chaumontet, M | 1 |
| Capt, M | 1 |
| Gold-Aubert, P | 1 |
| Molle, M | 1 |
| Kato, Y | 1 |
| Ohgo, S | 1 |
| Chihara, K | 1 |
| Imura, H | 1 |
| Czarnecka, K | 1 |
| Strocchi, P | 1 |
| Gandolfi, O | 1 |
| Montanaro, N | 1 |
| Geber, J | 1 |
| Suchanek, E | 1 |
| Ivanović, D | 1 |
| Gjuris, V | 1 |
| Aleksić, J | 1 |
| Reić, P | 1 |
| Marović, A | 1 |
| Gallioli, G | 1 |
| Grassi, E | 1 |
2 trials available for sulpiride and Stomach Ulcer
| Article | Year |
|---|---|
[The effect of sulpirid in treatment of patients with gastric and duodenal erosions and ulcers].
Topics: Adolescent; Adult; Aged; Dopamine Antagonists; Duodenal Ulcer; Female; Humans; Male; Middle Aged; St | 2007 |
[Sulpiride in the management of gastroduodenal ulcers. A comparative double-blind study].
Topics: Adult; Aged; Clinical Trials as Topic; Duodenal Ulcer; Female; Gastrointestinal Motility; Humans; Hy | 1975 |
19 other studies available for sulpiride and Stomach Ulcer
| Article | Year |
|---|---|
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA, Ba | 2006 |
Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chemistry, Pharmaceutical; | 2007 |
Differential response of A 68930 and sulpiride in stress-induced gastric ulcers in rats.
Topics: Adrenal Glands; Animals; Chromans; Corticosterone; Dinoprostone; Dopamine D2 Receptor Antagonists; G | 2010 |
Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions.
Topics: Animals; Antipsychotic Agents; Capillary Permeability; Dinoprostone; Disease Models, Animal; Dopamin | 2011 |
[Role of dopamine receptors in the mechanism of formation of stress-induced stomach lesions].
Topics: Animals; Apomorphine; Female; Gastrointestinal Hemorrhage; Humans; Levodopa; Male; Metoclopramide; R | 1984 |
Sulpiride specifically attenuates psychological stress-induced gastric lesions in rodents.
Topics: Animals; Anti-Ulcer Agents; Famotidine; Gastric Acid; Indomethacin; Male; Mice; Mice, Inbred ICR; Py | 1995 |
Gastric and duodenal anti-ulcer activity of sulpiride, a dopamine D2 receptor antagonist, in rats.
Topics: Animals; Anti-Ulcer Agents; Carbohydrate Metabolism; Dopamine D2 Receptor Antagonists; Duodenal Ulce | 1994 |
A differential dopamine receptor involvement during stress ulcer formation in rats.
Topics: Animals; Benzazepines; Bromocriptine; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor An | 1994 |
Brain-mediated protective interactions of histaminergic H2 and dopaminergic systems in rats.
Topics: Animals; Apomorphine; Bromocriptine; Cimetidine; Domperidone; Dopamine Agonists; Dopamine Antagonist | 1997 |
Symptomatic primary biliary cirrhosis triggered by administration of sulpiride.
Topics: Aged; Biopsy; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Liver; | 1999 |
L -sulpiride, at antidepressant dosage, prevents conditioned-fear stress-induced gastric lesions in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Conditioning, Psychological; Dose-Response Relati | 2000 |
Inhibitory effect of sulpiride on cinchophen gastric ulceration in dogs.
Topics: 11-Hydroxycorticosteroids; Animals; Behavior, Animal; Body Weight; Dogs; Drug Implants; Eating; Gast | 1977 |
[Effect of sulpiride in gastroenterology].
Topics: Animals; Dogs; Humans; Peptic Ulcer Hemorrhage; Rats; Stomach Ulcer; Sulpiride | 1979 |
Comparative study of two anti-ulcerogenic drugs--glaziovine and sulpiride.
Topics: Animals; Anti-Ulcer Agents; Aporphines; Female; Guinea Pigs; Histamine; Male; Pylorus; Rats; Reserpi | 1978 |
Stimulation of human prolactin secretion by sulpiride.
Topics: Adolescent; Adult; Chlorpromazine; Female; Humans; Male; Prolactin; Stimulation, Chemical; Stomach U | 1975 |
[Eglonyl in the treatment of peptic ulcer].
Topics: Drug Evaluation; Duodenal Ulcer; Female; Humans; Male; Stomach Ulcer; Sulpiride | 1976 |
Effect of single and repeated administration of sulpiride on the restraint ulcer in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Immobilization; Injections, | 1976 |
The role of dopamine in the formation of gastric ulcers in rats.
Topics: Animals; Apomorphine; Bromocriptine; Domperidone; Dopamine; Female; Haloperidol; Levodopa; Male; Rat | 1985 |
[Therapeutic activity of sulpiride in gastroduodenal ulcer].
Topics: Adult; Aged; Body Weight; Drug Evaluation; Drug Tolerance; Duodenal Ulcer; Female; Gastric Juice; Ga | 1974 |