sulpiride has been researched along with Postoperative Nausea and Vomiting in 2 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Postoperative Nausea and Vomiting: Emesis and queasiness occurring after anesthesia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Across the two studies, 689 patients were randomized and dosed with study medication, of whom 626 were evaluable per protocol." | 2.84 | Intravenous Amisulpride for the Prevention of Postoperative Nausea and Vomiting: Two Concurrent, Randomized, Double-blind, Placebo-controlled Trials. ( Bergese, SD; Candiotti, KA; Chassard, D; Diemunsch, P; Eberhart, L; Fox, G; Gan, TJ; Kovac, AL; Kranke, P; Leiman, DG; Melson, TI; Minkowitz, HS; Motsch, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kranke, P | 2 |
| Eberhart, L | 2 |
| Motsch, J | 2 |
| Chassard, D | 2 |
| Wallenborn, J | 1 |
| Diemunsch, P | 2 |
| Liu, N | 1 |
| Keh, D | 1 |
| Bouaziz, H | 1 |
| Bergis, M | 1 |
| Fox, G | 2 |
| Gan, TJ | 2 |
| Minkowitz, HS | 1 |
| Bergese, SD | 1 |
| Leiman, DG | 1 |
| Melson, TI | 1 |
| Kovac, AL | 1 |
| Candiotti, KA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomised, Double-blind, Placebo-controlled, Dose-ranging Phase II Study of APD421 for the Prevention of Post-operative Nausea and Vomiting[NCT01510704] | Phase 2 | 215 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01510704)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Placebo | 37 |
| Low Dose APD421 | 28 |
| Mid Dose APD421 | 20 |
| High Dose APD421 | 30 |
2 trials available for sulpiride and Postoperative Nausea and Vomiting
| Article | Year |
|---|---|
I.V. APD421 (amisulpride) prevents postoperative nausea and vomiting: a randomized, double-blind, placebo-controlled, multicentre trial.
Topics: Adult; Aged; Aged, 80 and over; Amisulpride; Anesthesia, Inhalation; Antiemetics; Dopamine Antagonis | 2013 |
Intravenous Amisulpride for the Prevention of Postoperative Nausea and Vomiting: Two Concurrent, Randomized, Double-blind, Placebo-controlled Trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amisulpride; Dopamine Antagonists; Double-Blind Method; | 2017 |