sulpiride has been researched along with Parkinsonian Disorders in 13 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Evaluation revealed levosulpiride, a dopamine receptor blocker commonly used for dyspepsia, to be the culprit." | 3.91 | An Unusual Cause of Camptocormia. ( Kumar, R; Lal, V; Mehta, S, 2019) |
| " Adverse effects include acute dyskinesia or Parkinsonism, which may occur after many months of treatment." | 2.43 | The safety of veralipride. ( De Leo, V; Delia, A; Faldini, E; Morgante, G; Musacchio, MC; Petraglia, F, 2006) |
| "Chronic pain is a common and undertreated nonmotor symptom in Parkinson's disease (PD)." | 1.62 | D2 receptor activation relieves pain hypersensitivity by inhibiting superficial dorsal horn neurons in parkinsonian mice. ( Luan, YW; Tang, DL; Xiao, C; Zhou, CY, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, DL | 1 |
| Luan, YW | 1 |
| Zhou, CY | 1 |
| Xiao, C | 1 |
| Gómez-Paz, A | 1 |
| Drucker-Colín, R | 1 |
| Milán-Aldaco, D | 1 |
| Palomero-Rivero, M | 1 |
| Ambriz-Tututi, M | 1 |
| Mehta, S | 1 |
| Kumar, R | 1 |
| Lal, V | 1 |
| Pendolino, V | 1 |
| Bagetta, V | 1 |
| Ghiglieri, V | 1 |
| Sgobio, C | 1 |
| Morelli, E | 1 |
| Poggini, S | 1 |
| Branchi, I | 1 |
| Latagliata, EC | 1 |
| Pascucci, T | 1 |
| Puglisi-Allegra, S | 1 |
| Calabresi, P | 1 |
| Picconi, B | 1 |
| Ma, HI | 1 |
| Kim, JH | 1 |
| Chu, MK | 1 |
| Oh, MS | 1 |
| Yu, KH | 1 |
| Kim, J | 1 |
| Hahm, W | 1 |
| Kim, YJ | 1 |
| Lee, BC | 1 |
| Viaro, R | 1 |
| Marti, M | 1 |
| Morari, M | 1 |
| Jones, CA | 1 |
| Johnston, LC | 1 |
| Jackson, MJ | 1 |
| Smith, LA | 1 |
| van Scharrenburg, G | 1 |
| Rose, S | 1 |
| Jenner, PG | 1 |
| McCreary, AC | 1 |
| Martí Massó, JF | 1 |
| Ruiz-Martínez, J | 1 |
| Bergareche, A | 1 |
| López de Munain, A | 1 |
| Ohye, C | 1 |
| Shibazaki, T | 1 |
| Milusheva, E | 1 |
| Baranyi, M | 1 |
| Kittel, A | 1 |
| Sperlágh, B | 1 |
| Vizi, ES | 1 |
| De Leo, V | 1 |
| Morgante, G | 1 |
| Musacchio, MC | 1 |
| Faldini, E | 1 |
| Delia, A | 1 |
| Petraglia, F | 1 |
| Mehta, MA | 1 |
| Sahakian, BJ | 1 |
| McKenna, PJ | 1 |
| Robbins, TW | 1 |
| Galvan, A | 1 |
| Floran, B | 1 |
| Erlij, D | 1 |
| Aceves, J | 1 |
1 review available for sulpiride and Parkinsonian Disorders
| Article | Year |
|---|---|
The safety of veralipride.
Topics: Adult; Aged; Basal Ganglia Diseases; Dopamine D2 Receptor Antagonists; Estrogens; Female; Half-Life; | 2006 |
1 trial available for sulpiride and Parkinsonian Disorders
| Article | Year |
|---|---|
Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease.
Topics: Adult; Affect; Antipsychotic Agents; Association Learning; Attention; Cognition Disorders; Cross-Ove | 1999 |
11 other studies available for sulpiride and Parkinsonian Disorders
| Article | Year |
|---|---|
D2 receptor activation relieves pain hypersensitivity by inhibiting superficial dorsal horn neurons in parkinsonian mice.
Topics: Action Potentials; Animals; Chronic Pain; Dopamine Agonists; Dopamine Antagonists; Indoles; Male; Mi | 2021 |
Intrastriatal Chromospheres' Transplant Reduces Nociception in Hemiparkinsonian Rats.
Topics: Animals; Cells, Cultured; Male; Microinjections; Naltrexone; Nociception; Oxidopamine; Pain Measurem | 2018 |
An Unusual Cause of Camptocormia.
Topics: Aged; Brain; Diabetes Complications; Diagnosis, Differential; Dopamine Antagonists; Dyspepsia; Femal | 2019 |
l-DOPA reverses the impairment of Dentate Gyrus LTD in experimental parkinsonism via β-adrenergic receptors.
Topics: Animals; Antiparkinson Agents; Benzazepines; Dentate Gyrus; Disease Models, Animal; Dopamine; Dopami | 2014 |
Diabetes mellitus and drug-induced Parkinsonism: a case-control study.
Topics: Age of Onset; Aged; Contraindications; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Sus | 2009 |
Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade.
Topics: Amisulpride; Animals; Antiparkinson Agents; Benzimidazoles; Benzothiazoles; Dopamine Antagonists; Do | 2010 |
An in vivo pharmacological evaluation of pardoprunox (SLV308)--a novel combined dopamine D(2)/D(3) receptor partial agonist and 5-HT(1A) receptor agonist with efficacy in experimental models of Parkinson's disease.
Topics: Animals; Apomorphine; Benzoxazoles; Callithrix; Dopamine Agonists; Female; Male; Mice; Motor Activit | 2010 |
[Parkinsonism induced by sulpiride and veralipride: two different stories].
Topics: Adult; Aged; Brain Damage, Chronic; Contraindications; Dyskinesia, Drug-Induced; Europe; Female; Hum | 2011 |
Lesioning the thalamus for dyskinesia.
Topics: Antiparkinson Agents; Antipsychotic Agents; Dyskinesia, Drug-Induced; Dyskinesias; Electrocoagulatio | 2001 |
Increased sensitivity of striatal dopamine release to H2O2 upon chronic rotenone treatment.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Hydrogen Peroxide; Male; Oxidative Stress; Parkin | 2005 |
Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat.
Topics: Animals; Apomorphine; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; gamma-Aminobu | 2001 |