Page last updated: 2024-11-04

sulpiride and Obsessive-Compulsive Disorder

sulpiride has been researched along with Obsessive-Compulsive Disorder in 16 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to investigate the prevalence rates of obsessive-compulsive disorder (OCD) and hypochondriasis in schizophrenic patients treated with atypical antipsychotics (AAPs) and to investigate the different comorbidity rates of OCD and hypochondriasis between clozapine-treated patients and patients treated with other AAPs."7.80Hypochondriasis and obsessive-compulsive disorder in schizophrenic patients treated with clozapine vs other atypical antipsychotics. ( Cantisani, A; Ferrari, G; Grassi, G; Pallanti, S; Poli, L; Righi, L, 2014)
"A 14-year-old boy with obsessive-compulsive disorder (OCD) developed, under fluvoxamine treatment, acute symptoms of Tourette's syndrome (TS) with aggravation of the OCD."7.69Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder. ( Fennig, S; Fennig, SN; Pato, M; Weitzman, A, 1994)
"Amisulpiride 200 mg/day was added to ongoing SRI treatment and titrated up to 600 mg/day in flexible doses."6.71Amisulpiride augmentation in treatment resistant obsessive-compulsive disorder: an open trial. ( Metin, O; Tot, S; Yazici, AE; Yazici, K, 2003)
"The aim of the study was to investigate the prevalence rates of obsessive-compulsive disorder (OCD) and hypochondriasis in schizophrenic patients treated with atypical antipsychotics (AAPs) and to investigate the different comorbidity rates of OCD and hypochondriasis between clozapine-treated patients and patients treated with other AAPs."3.80Hypochondriasis and obsessive-compulsive disorder in schizophrenic patients treated with clozapine vs other atypical antipsychotics. ( Cantisani, A; Ferrari, G; Grassi, G; Pallanti, S; Poli, L; Righi, L, 2014)
"We stratified 70 patients with schizophrenia according to their mode of antipsychotic treatment: clozapine and olanzapine (group I) compared with aripiprazole and amisulpride (group II)."3.77Antiserotonergic antipsychotics are associated with obsessive-compulsive symptoms in schizophrenia. ( Englisch, S; Esslinger, C; Meyer-Lindenberg, A; Rausch, F; Schirmbeck, F; Zink, M, 2011)
"A 14-year-old boy with obsessive-compulsive disorder (OCD) developed, under fluvoxamine treatment, acute symptoms of Tourette's syndrome (TS) with aggravation of the OCD."3.69Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder. ( Fennig, S; Fennig, SN; Pato, M; Weitzman, A, 1994)
"Amisulpiride 200 mg/day was added to ongoing SRI treatment and titrated up to 600 mg/day in flexible doses."2.71Amisulpiride augmentation in treatment resistant obsessive-compulsive disorder: an open trial. ( Metin, O; Tot, S; Yazici, AE; Yazici, K, 2003)
"Patients with Tourette's syndrome often develop multiple psychopathological symptoms beyond the basic symptoms (motor and vocal tics)."1.31[Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear]. ( Barnett, W; Bednarz, K; Haisch, S, 2002)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naguy, A1
Grassi, G1
Poli, L1
Cantisani, A1
Righi, L1
Ferrari, G1
Pallanti, S1
Mendhekar, DN1
Schirmbeck, F1
Esslinger, C1
Rausch, F1
Englisch, S1
Meyer-Lindenberg, A1
Zink, M1
Ersche, KD2
Cumming, P1
Craig, KJ2
Müller, U2
Fineberg, NA2
Bullmore, ET2
Robbins, TW2
Roiser, JP1
Abbott, S1
Suckling, J1
Ooi, C1
Shabbir, SS1
Clark, L1
Sahakian, BJ1
Merlo-Pich, EV1
Rickards, H1
Cavanna, AE1
Worrall, R1
Bednarz, K1
Haisch, S1
Barnett, W1
Metin, O1
Yazici, K1
Tot, S1
Yazici, AE1
Poyurovsky, M1
Weizman, R1
Weizman, A1
Koran, L1
Kim, SW1
Shin, IS1
Kim, JM1
Yang, SJ1
Hwang, MY1
Yoon, JS1
Fennig, S1
Fennig, SN1
Pato, M1
Weitzman, A1
George, MS1
Trimble, MR1
Sevincok, L1
Uslu, A1
Kaynak, H1
Dereboy, F1
Baving, L1
Schmidt, MH1
Stárková, L1
Wiedermann, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Augment in Treatment-resistent Obsessive-compulsive Disorder: an Open-label Trial[NCT00590642]30 participants (Anticipated)Observational2006-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for sulpiride and Obsessive-Compulsive Disorder

ArticleYear
Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist.
    Biological psychiatry, 2011, Oct-15, Volume: 70, Issue:8

    Topics: Adult; Amisulpride; Amphetamine-Related Disorders; Benzothiazoles; Brain Mapping; Cocaine-Related Di

2011
Amisulpiride augmentation in treatment resistant obsessive-compulsive disorder: an open trial.
    Human psychopharmacology, 2003, Volume: 18, Issue:6

    Topics: Adult; Aged; Amisulpride; Antidepressive Agents; Antipsychotic Agents; Drug Resistance; Drug Therapy

2003
Dystonic reaction associated with fluvoxamine.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Dystonia; F

1993

Other Studies

13 other studies available for sulpiride and Obsessive-Compulsive Disorder

ArticleYear
An Adult With Obsessive-Compulsive-Related Disorders and Tics Post-Carbon Monoxide Poisoning Who Responded Ultimately to Electroconvulsive Therapy.
    The journal of ECT, 2019, Volume: 35, Issue:2

    Topics: Adult; Antipsychotic Agents; Carbon Monoxide Poisoning; Combined Modality Therapy; Electroconvulsive

2019
Hypochondriasis and obsessive-compulsive disorder in schizophrenic patients treated with clozapine vs other atypical antipsychotics.
    CNS spectrums, 2014, Volume: 19, Issue:4

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Comorbidity; Fem

2014
Hyperpigmentation with amisulpride.
    The Australian and New Zealand journal of psychiatry, 2009, Volume: 43, Issue:1

    Topics: Adult; Amisulpride; Antipsychotic Agents; Chronic Disease; Drug Therapy, Combination; Female; Fluvox

2009
Antiserotonergic antipsychotics are associated with obsessive-compulsive symptoms in schizophrenia.
    Psychological medicine, 2011, Volume: 41, Issue:11

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Comorbidity; Fem

2011
Amisulpride-induced acute akathisia in OCD: an example of dysfunctional dopamine-serotonin interactions?
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:6

    Topics: Adult; Akathisia, Drug-Induced; Amisulpride; Dopamine; Female; Humans; Male; Obsessive-Compulsive Di

2012
Treatment practices in Tourette syndrome: the European perspective.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:4

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Atomoxetine Hydrochloride

2012
[Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear].
    Der Nervenarzt, 2002, Volume: 73, Issue:9

    Topics: Adult; Anxiety Disorders; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Combined Modality

2002
Memantine for treatment-resistant OCD.
    The American journal of psychiatry, 2005, Volume: 162, Issue:11

    Topics: Adult; Clomipramine; Dopamine Antagonists; Drug Therapy, Combination; Excitatory Amino Acid Antagoni

2005
Amisulpride improves obsessive-compulsive symptoms in schizophrenia patients taking atypical antipsychotics: an open-label switch study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Comorbidity; Dopamine Antagonists; Dose-Resp

2008
Emergence of symptoms of Tourette's syndrome during fluvoxamine treatment of obsessive-compulsive disorder.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:6

    Topics: Adolescent; Arousal; Drug Therapy, Combination; Fluvoxamine; Humans; Loxapine; Male; Neurologic Exam

1994
Sulpiride addition in a case of fluvoxamine-refractory obsessive-compulsive disorder without comorbid psychopathology.
    Journal of psychiatry & neuroscience : JPN, 2000, Volume: 25, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Female; Fluvoxamine; Humans; Middle Aged; Obsessive-Compul

2000
[Obsessive-compulsive disorder, frontostriatal system and the effect of the serotonergic system].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2000, Volume: 28, Issue:1

    Topics: Adolescent; Behavior Therapy; Child; Clomipramine; Combined Modality Therapy; Female; Fluvoxamine; H

2000
Our experience with incisive neuroleptic drugs in child psychiatry.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1991, Volume: 131

    Topics: Antipsychotic Agents; Autistic Disorder; Child; Haloperidol; Humans; Mental Disorders; Obsessive-Com

1991